Tostran Gel is applied to clean dry skin on the abdomen or on the inner thighs (half the dose on each inner thigh); it's recommended that both of these parts of the body are used on different days. It should not be applied to the genitals. The gel should be applied once a day, at about the same time of day; preferably in the morning. If you have a bath or shower in the morning, the gel should be applied after you have washed and dried the skin, not before you have washed: it's recommended that you do not wash the area for at least 6 hours after the gel has been applied, otherwise the amount of testosterone absorbed by the body will be reduced.
Before using Tostran Gel for the first time, the pump needs to be primed, by depressing the piston 8 times. Any gel that is dispensed should be discarded. This only needs doing once for each canister; the canister should then be kept upright while it's in use.
The normal daily starting dose is 3g of gel (60mg of testosterone; 6 depressions of the Tostran pump). Sometimes a higher or lower dose is recommended by the doctor, depending on the response and your general health. The amount used each day should not exceed 4g of gel (80mg of testosterone; 8 depressions of the pump).
The required amount of gel should be put on to one finger, and then rubbed in gently to the abdomen or the inner thighs as above. The hands should then be washed, and dressing can continue after the gel has dried on the skin which usually only takes a few minutes.
The patient information leaflet gives more detail about how the gel should be applied to the skin.
Preventing the gel transferring on to other people
There is a chance that the gel - and therefore testosterone - can be transferred from one person to another by skin contact with the parts of the body that the gel was rubbed in to. This can cause side effects in people who have made contact in this way, even if it is a small amount of contact but over a long period of time. It is important to prevent this happening, especially where contact with pregnant women or children is likely. The product leaflet gives details about how to do this, but briefly, you should wash your hands after applying the gel, cover the application site with clothing after the gel has dried, and shower before any such contact is anticipated (such as sexual contact).