Crestor is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Rosuvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).
Crestor is used to lower cholesterol and triglycerides (types of fat) in the blood.
Crestor is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors
Take Crestor exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Crestor is usually taken once a day, with or without food. Take the medicine at the same time each day. Your doctor may occasionally change your dose to make sure you get the best results.
You may need to stop using Crestor for a short time if you have:
an electrolyte imbalance (such as high or low potassium levels in your blood);
severely low blood pressure;
a severe infection or illness;
surgery or a medical emergency.
To be sure Crestor is helping your condition and is not causing harmful effects, your blood will need to be tested often. Visit your doctor regularly.
Crestor is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
You may need to take Crestor on a long-term basis for the treatment of high cholesterol. Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
et emergency medical help if you have any of these signs of an allergic reaction to Crestor: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Crestor and call your doctor at once if you have any of these serious side effects:
unexplained muscle pain, tenderness, or weakness;
confusion, memory problems;
fever, unusual tiredness, and dark colored urine;
swelling, weight gain, urinating less than usual or not at all;
increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness,dry skin, blurred vision, weight loss; or
nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious Crestor side effects may include:
headache, depressed mood;
mild muscle pain;
sleep problems (insomnia), nightmares;
mild nausea; or
stomach pain or indigestion.
You should not take Crestor if you are allergic to rosuvastatin, if you are pregnant or breast-feeding, or if you have liver disease.
To make sure you can safely take Crestor, tell your doctor if you have any of these other conditions:
- history of liver disease;
- history of kidney disease;
a thyroid disorder; or
if you drink more than 2 alcoholic beverages daily.
People of Asian descent may absorb rosuvastatin at a higher rate than other people. Make sure your doctor knows if you are Asian. You may need a lower than normal starting dose.
In rare cases, Crestor can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).
Tell your doctor about all other medications you use. Certain other drugs can increase your risk of serious muscle problems, and it is very important that your doctor knows if you are using any of them:
cyclosporine (Gengraf, Neoral, Sandimmune);
gemfibrozil (Lopid), fenofibric acid (Fibricor, Trilipix), or fenofibrate (Antara, Fenoglide, Lipofen, Lofibra, Tricor, Triglide);
HIV medications such as atazanavir (Reyataz), ritonavir (Norvir), lopinavir/ritonavir (Kaletra), saquinavir (Invirase), and others; or
medicines that contain niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others).
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