Enalapril belongs to a group of medicines called Angiotensin converting enzyme inhibitors (ACE inhibitors). It works by causing blood vessels to relax, lowering blood pressure and increasing the supply of blood and oxygen to the heart.
Enalapril maleate Tablets are used to treat:
- Hypertension (high blood pressure).
Always take your medicine exactly as directed by your doctor. If you are unsure about how to take your tablets, ask your doctor or pharmacist.
You should take your tablet at the same time each day unless your doctor tells you otherwise. If you are taking your medicine twice daily (2 tablets a day), take one tablet in the morning and one in the evening, unless your doctor told you otherwise.
Usual oral dose to be swallowed with a glass of water:
The starting dose is 2.5mg or 5mg a day. The dosage is gradually increased up to 10 to 20mg a day either once daily or twice daily according to your doctor's advice. The maximum dose is 40mg a day.
Elderly (65 years old and over):
A starting dose of 2.5mg is recommended.
A starting dose of 2.5mg is recommended as directed by your doctor.
Children: Not for use in children.
If you take more Enalapril maleate Tablets than you should
Do not take more medicine than your doctor tells you to. If you or anyone else has swallowed a lot of tablets, contact your nearest hospital casualty department or doctor immediately.
If you forget to take Enalapril maleate Tablets
If you forget to take a dose, take it as soon as you remember, then continue the usual. Do not take a double dose to make up for a forgotten dose.
If you stop taking Enalapril maleate Tablets
Do not stop taking your medicine, unless your doctor has told you to. If you do, your blood pressure may increase. If your blood pressure becomes too high it may affect your heart and kidneys.
If you have any further questions on the use of these product, ask your doctor or pharmacist.
Like all medicines Enalapril maleate Tablets can cause side effects, although not everybody gets them.
If you develop any of the following reactions stop taking these tablets and contact your doctor immediately:
- If you develop severe dizziness or lightheadedness (especially at the start of treatment or when the dose is increased)
- Swelling of the hands, face, lips or tongue
- Difficulty in breathing,
- A sudden, unexpected rash or burning, red or peeling skin.
- Sore throat or fever,
Other possible side effects
Common side effects (affecting between 1 in 10 and 1 in 100 people)
- Feeling sick (nausea)
- Diarrhoea, fluid retention (oedema)
- Headache, depression
- Low blood pressure, fainting
- Weakness or fatigue
- Blurred vision
- Chest pain, irregular heartbeat, chest pain, fast heart beat
- Swelling of the hands, face, lips or tongue(angiodema)
- Increased blood potassium level
Do not take Enalapril maleate Tablets
- If you are allergic (hypersensitive) to enalapril maleate, any of the other ingredients in these tablets or other ACE inhibitors(see Section 6 and end of Section 2)
- If you have previously developed swelling especially over the face, lips or mouth, rashes or difficulty breathing after taking medicines.
- If you are or think you may be pregnant
Take special care with Enalapril maleate Tablets
You should let your doctor know:
- If you have any of the following heart diseases: heart failure, narrowing (stenosis) of the opening of the aortic or mitral valve or enlarged heart (hypertrophic cardiomyopathy).
- If you have a history of "angioeodema" while taking other medicines. The signs may have been itching, wheezing or swelling of the hands, mouth and throat.
- If you have kidney disease, have had a recent kidney transplantation, are dialysis patients, are taking diuretics (water tablets).
- If you are on a salt restriction diet, or have suffered from excessive vomiting, diarrhoea or dehydration.
- If you are taking potassium containing medicines or supplements, salt substitutes or low-salt milk.
- If you are taking lithium, used for the treatment of some psychiatric illnesses.
- If you develop a dry cough which is persistent for a long time
- If you develop jaundice (yellowing of the skin and white of the eyes)
- If you are receiving desensitisation treatment with hymenoptera venom (e.g. bee or wasp venom)
- If you are receiving a treatment called LDL apheresis to remove cholesterol from your blood machine
- If you need to undergo surgery or receive anesthetics (even at dentist).
Taking other medicine
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines including medicines obtained without a prescription.
It is especially important to tell your doctor if you are taking any of the following:
- Water tablets (diuretics) such as thiazides, furosemide
- Other medicine that lower blood pressure, such as nitroglycerine, nitrates, vasodilators
- Lithium, used for the treatment of some psychiatric illnesses
- Tricyclic antidepressants such as amitriptyline used to treat depression
- Pain killer such as morphine or anesthetics
- Barbiturates (sedatives used for sleeplessness or epilepsy)
- Cholestyramine (used to help control cholesterol levels)
- Medicines for the treatment of cancer
- Antidiabetic drugs including oral agents to lower blood sugar and insulin
- Allopurinol (used to treat gout)
- Ciclosporin (Immunosuppressive agents of autoimmune disorders)
- Procainamide use to treat abnormal heart rhythms
- Non-steroidal anti-inflammatory drugs (NSAIDs) such as diclofenac
- Corticosteriods (used to treat certain conditions such as rheumatism, arthritis, allergic conditions, asthma or certain blood disorders)
- Antacids ( used for the relief of indigestion)
Taking Enalapril maleate Tablets with food and drink
Enalapril maleate Tablets can be taken with or without a meal. Do not drink alcohol whilst taking Enalapril maleate Tablets. It may cause your blood sugar levels to drop too much and you may experience dizziness, light-headedness or fainting.
Pregnancy and breast-feeding
Tell your doctor before taking Enalapril maleate Tablets if you are pregnant, planning to become pregnant or breast-feeding.
Driving using machine
As this medicine may make you feel dizzy, you should not drive or operate machinery until you know how the drug affects you.
Important information about some of the ingredients of Enalapril maleate Tablets
This product contains lactose - if you know you have an intolerance to some sugars, contact your doctor before use.
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