Evorel Sequi belongs to a group of medicines called hormone replacement therapy (more commonly known as HRT). Evorel Sequi contains two medicines: Oestrogen (Estradiol) and Progestogen (Norethisterone), of which are both female hormones. They come in a memory pack to assist you to remember when to change your patches. Each pack contains eight patches; 4x Evorel 50 patches containing Estradiol only and 4x Evorel conti patches containing both Estradiol and Norethisterone. The hormones are spread evenly in each patch.
Evorel Sequi is used for the symptoms of the menopause. It is only used in women who still have a womb. It is suitable for women who have had the menopause or who are around the time of the menopause. Evorel is also taken to prevent Osteoporosis (fragile bones) in women who have had the menopause and are most likely to have bone problems. Evorel Sequi is only used if other medicines for Osteoporosis have been tried first and they have not worked.
Evorel Seuqi is known as continuous sequential HRT. This is because two hormones are used one after another. Estradiol is used by itself for two weeks then the Estradiol and Norethisterone are used together for the next two weeks. Evorel Sequi patches replace te oestrogen that is normally released by the ovaries. However taking an oestrogen hormone regularly may cause the lining of your womb to build up and get thicker. This means it is necessary to add a progestogen hormone to the oestrogen. This helps shed the lining of the womb and stop any problems happening.
Use Evorel as advised by your doctor. If you are unsure seek medical advice. You can apply an Evorel patch anytime if you have not been using another form of HRT treatment, your menstrual cycles are not regular or changing from HRT that does not give you a withdrawal bleed.
The patch should be changed twice a week. Do not leave a break between each patch to ensure a regular supply of hormones is delivered. Change your patch the same two days every week. Week 1 and 2 use the four Evorel 50 patches one at a time and week 3 and 4 use the four Evorel conti patches one at a time. Most women prefer to wear the patch on the thigh or bottom. Do not apply on or near the breasts. Do not apply the patch on the same area of skin twice in a row. Do not wear the patch under elasticated areas or a tight waistband. Apply the patch to clean, dry cool skin as soon as you open the protective pouch.
Open and peel- using the notches as a guide, tear along two edges of the pouch. Remove the patch. With the protective backing facing you, bend and feel off half the backing. Do not touch the sticky side, it may not stick properly. Apply and press- apply the open half of the patch to your skin. Remove the remaining backing and press down the rest of the path. Press the patch with the palm of your hand to make sure it is firmly stuck down.
The active ingredients in Evorel Sequi are Estradiol Hemihydrate and Northisterone Acetate. Each Evorel 50 patch contains 3.2mg of Estradiol Hemihydrate. Each Evorel 50 patch delivers 50 mg of Estradiol a day. Each Evorel Conti patch contains 3.2mg of Estradiol Hemihydrate and 11.2mg of Norethisterone Acetate. Each patch delivers 50mg of Estradiol and 170mg of Norethisteone a day.
A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.
Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.
Some side-effects may be serious while others may only be a mild inconvenience.
Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.
Very common: More than 1 in 10 people who use Evorel
- application site problems such as redness, itching, rashes or oedema
Common: More than 1 in 100 people who use Evorel
- breast pain
- feeling dizzy
- headaches– seek immediate medical advice if you have an unusually bad headache
- menstrual problems including painful, heavy or long menstrual periods, bleeding or spotting between menstrual periods - some of these problems may happen within the first few months of starting treatment with Evorel or if you forget to apply your patch. If this continues to happen once Evorel has been used for some time or after you have stopped using Evorel you must contact your prescriber
- migraine– seek immediate medical advice if you get a migraine-type headache for the first time
- skin rash or rashes
- weight gain
Keep out of the reach and sight of children. Use as directed by your doctor. Do not use Evorel if you are allergic to any of the ingredients, ever had breast cancer, if you have a thickening of the lining of the womb, vaginal bleeding which you cannot explain, ever had blood clots, if you have liver disease, blocked arteries. Tell your doctor if you are taking any other medication. Do not use if you are pregnant or you might become pregnant and do not use if you are breast feeding.
All our orders are sent out using Royal Mail. Tracking is available on all orders.
We always aim to dispatch all orders within 24 hours of them being received, if we are unable to meet this
high standard for whatever reason we will always contact you to advise you of the delay.
We offer free UK standard delivery on orders over £40.
The following delivery options are available:
- Standard Delivery - 2/3 day delivery - £2.95
- Express Delivery - 1/2 day delivery - £4.45
- Special Delivery (Guaranteed before 1pm) - £8.95
- Saturday Guaranteed before 1pm - £10.45
The cut-off for same day dispatch of orders is 4pm. Orders processed after this time will be dispatched the following working day. Orders are dispatched Monday - Friday. Orders will not be processed on weekends or bank holidays.
We ensure all deliveries are in plain packaging for discreet delivery of your medicines and pharmacy goods.
Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt.
Delivery is free for all NHS prescriptions.
Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering.
We are currently unable to ship orders outside of the UK.