Lansoprazole is a generic drug used to treat certain conditions where there is too much acid in the stomach. It is used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus.
Lansoprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.
Gastro-oesophageal reflux disease (GORD) is a digestive condition that commonly occurs in one in five people. It can affect people of all ages, including children. It is most common in adults aged 40 and over and occurs more in men than in women.
Acid reflux occurs when stomach acid leaks out of the stomach and into the gullet (oesophagus), which is a long tube that runs from the mouth to the stomach. Acid reflux is most commonly caused by weakening of the lower sphincter muscles of the gullet.
The common symptoms of GORD (acid reflux) include:
- Heartburn – a burning pain or discomfort below the breastbone, usually worse after meals,
- or when bending down, or when lying down
- An unpleasant taste in the mouth, caused by reflux of acid from the stomach
- Pain and difficulty in swallowing (dysphagia)
Most people respond well to treatment with medication and some people may require a long-term course of medication to control the symptoms of acid reflux.
Swallow these capsules whole with a glass of water, preferably at the same time each day, in the morning before a meal. If the capsules are to be taken twice a day, then the second dose should be taken before the evening meal. Do not crush or chew the capsules
Taking lansoprazole with food and drink
You should take lansoprazole at least 30 minutes before food.
Driving and using machines
You may feel dizzy, tired, sick, have a headache or problems with your eyesight while taking lansoprazole. If this happens, do not drive or use any tools or machines.
Common (affects less than 1 in 10 people)
• headaches, feeling dizzy or tired, or a general feeling of being unwell
• diarrhoea, constipation, stomach pains, feeling sick (nausea) or being sick (vomiting), wind
• dry or sore mouth or throat
• skin rash, itching
• changes in the way your liver is working
(shown by a blood test)
Do not take lansoprazole and tell your doctor if:
• You are allergic (hypersensitive) to lansoprazole or any of the other ingredients of these capsules (listed in section 6: Further Information)
Signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue
• You are taking a medicine containing atazanavir (used to treat HIV).
Do not take lansoprazole if any of the above applies to you. If you are not sure, talk to your doctor or pharmacist.
Take special care and check with your doctor before taking lansoprazole if:
• You have liver problems Your doctor may want
to adjust your dose.
• Your doctor may arrange for you to have an
endoscopic examination (where a very small camera is inserted down your oesophagus (food pipe) to look into your stomach). This will help find out what is causing your symptoms. It can help to exclude more serious causes of your symptoms such as stomach cancer.
• Your doctor has given you lansoprazole in addition to other medicines intended for the treatment of Helicobacter pyloriinfection (antibiotics): please also read the package leaflets of these medicines carefully.
• If you take lansoprazole on a long-term basis (longer than 1 year) your doctor will probably ask to see you regularly so he can check how well you are doing. Tell your doctor if you notice any new symptoms or if any of your symptoms are getting worse.
If you are not sure if any of the above applies to you, talk to your doctor or pharmacist before taking lansoprazole. Do this even if they applied only in the past.
Taking a proton pump inhibitor like lansoprazole, especially over a period of more than one year, may slightly increase your risk of fracture in the hip, wrist or spine. Tell your doctor if you have osteoporosis or if you are taking corticosteroids (which can increase the risk of osteoporosis).
Taking lansoprazole with other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. This includes herbal medicines. This is because lansoprazole can affect the way some other medicines work. Also, some medicines can affect on the way lansoprazole works.
In particular, check with your doctor or pharmacist if you are taking any of the following medicines:
• Ketoconazole, itraconazole, rifampicin (used to
• Digoxin(used to treat heart problems)
• Theophylline (used to treat asthma)
• Tacrolimus (used to prevent transplant rejection) • Fluvoxamine (used to treat depression and
other psychiatric problems)
• Antacids (used to treat heartburn or acid
• Sucralfate (used for healing ulcers)
• St John’s wort sometimes called Hypericum
perforatum (used to treat mild depression) If you are not sure, talk to your doctor or pharmacist before taking lansoprazole.
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