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Lariam 250mg Tablets

Lariam 250mg Tablets

Pack Size: All treatments are complete courses that include tablets for before and after your trip.
Our Price: £30.90
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Age: 18 years +

Lariam 250mg tablets are available to order online from The Independent Pharmacy Online Doctor. Lariam tablets contain the active ingredient mefloquine and are a convenient once-weekly treatment for malaria prevention and are effective in a number of countries around the world.

Pharmacist Tip

Wear loose fitting clothing; mosquitos can bite through tight clothing. You should wear long trousers and sleeves, especially at dawn and dusk when mosquitos are most active.

Lariam 250mg Tablets are available to buy from The Independent Pharmacy Online Doctor service, following a free consultation, to help prevent malaria. To find out more about malaria and see all the available treatments, see our Online Doctor Malaria page.

Lariam Tablets are mainly used for the prevention and treatment of malaria. Each Lariam Tablet contains 250mg of the active ingredient, Mefloquine Hydrochloride. Lariam is classified as a prescription-only-medicine (POM) and is manufactured by Roche. The tablets are white and crossed-scored.

Malaria is caused by varying types of parasites called plasmodium. Mosquitos infected with plasmodium can pass them to humans through biting. If bitten by an infected mosquito the plasmodium will be injected into the human bloodstream where it will begin to multiply. This can result in malaria.

Mefloquine belongs to a group of medicines called antimalarials. Mefloquine works by attacking and killing the malaria causing parasite once it has entered the red blood cells. This action prevents the parasites from increasing in numbers and spreading.

Mefloquine is effective at combating the strain of malaria caused by the plasmodium falciparum. In areas where this particular parasite in present, Lariam may be judged the suitable course of prevention. It can also be used in areas where there is a known resistance to alternative antimalarial treatments, such as Chloroquine.

If Lariam is deemed to be the appropriate antimalarial for you, treatment will need to commence prior to travel (2-3 weeks) and continue after you have left the malaria zone (4 weeks). This is to ensure that enough of the drug has built up in your system to protect you upon arrival and that there is still enough Mefloquine in your bloodstream to eliminate any remaining parasites after you have departed.

The correct dosage of Lariam tablets is dependent on body weight. Adults, who weigh more than 45kg, should take one whole tablet once a week.

Pharmacist Tip: Mefloquine is not suitable in pregnancy or during breastfeeding, or for patients with epilepsy or those who will be at altitude or scuba diving. 

  • You should take one tablet every week on the same day each week.
  • Lariam needs to be taken three weeks before entering an area where malaria is present and continued until four weeks after leaving the malaria area.
  • You should take Lariam with or after food.
  • Lariam remains effective with a moderate alcohol intake.

Lariam tablets contain the active ingredient mefloquine 250mg per tablet.

The other ingredients are poloxamer, microcrystalline cellulose, lactose, maize starch, crospovidone, ammonium calcium alginate, talc, magnesium stearate.

If you do experience side effects from Lariam they may include depression, mood changes, anxiety, confusion, hallucinations, panic attacks, restlessness, paranoia and general agitation. Lariam has a small risk of nausea, vomiting, diarrhoea, and skin rash as with all medicines. There have been rare reports of suicidal thoughts whilst taking Lariam. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Lariam should not cause a harmful interaction with any of your other current medicines. Lariam should not be taken if you currently take carbamazepine, chloroquine, halofantrine, ketoconazole, phenobarbital, phenytoin, quinidine, quinine, rifampicin, or valproic acid (valproate). Please read the Patient Information Leaflet enclosed with your medicines for further information.

Lariam is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods.

Remember it is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave. 

Remember, malaria can take up to a year to develop after you have been bitten. If you experience symptoms including headaches, night sweats and abdominal pain any time during your trip or up to one year afterwards you must see a doctor as soon as possible. 

You should take adequate contraceptive precautions to ensure you do not become pregnant whilst taking Lariam and for three months after you have finished the course.

Please seek medical help immediately if you experience serious mental problems while taking Lariam. Lariam should be stopped immediately and replaced with another medicine to prevent malaria.

Stop taking this medicine and contact your doctor immediately if you experience:

  • attempted suicide.
  • suicidal thoughts.
  • self-endangering behaviour.
  • allergic reaction (anaphylaxis) with symptoms such as difficulty in breathing, swollen tongue, itching and severe rash.
  • severe changes in texture and appearance of the skin, especially if it affects your mouth and eyes (Stevens Johnson syndrome).
  • psychosis (losing touch with reality).
  • severe anxiety.
  • panic attacks.
  • fits (seizures or convulsion).
  • fever, chills, cough, shortness of breath or chest pain. These could be signs of inflammation of the lungs also known as pneumonitis.
  • Severe liver problems which might be demonstrated by a transient increase in your liver enzymes shown by blood tests or other symptoms such as tender, firm or possibly enlarged liver, jaundice (yellowing of skin/eyes), dark urine, light coloured stools and generalised itchiness.
  • Pins and needles, weakness, numbness, new or worsening clumsiness or unsteadiness on your feet, or shaking of the hands and fingers.
  • Painful mouth or throat ulcers, fever, chills, bruises on the skin, nosebleeds, bleeding in the stomach or vaginal bleeding. These could be signs of blood disorders.
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All our orders are sent out using Royal Mail. Tracking is available on all orders. We always aim to dispatch all orders within 24 hours of them being received, if we are unable to meet this high standard for whatever reason we will always contact you to advise you of the delay.

We offer free UK standard delivery on orders over £40.

The following delivery options are available:

  • Standard Delivery - 2/3 day delivery - £2.95
  • Express Delivery - 1/2 day delivery - £4.45
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

The cut-off for same day dispatch of orders is 4pm. Orders processed after this time will be dispatched the following working day. Orders are dispatched Monday - Friday. Orders will not be processed on weekends or bank holidays.

We ensure all deliveries are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 


We are currently unable to ship orders outside of the UK.

The Independent Pharmacy is an online pharmacy and online doctor service is owned and operated by ABSM Healthcare Ltd (Company Reg. 08515600) and Red Label Medical Ltd (Company Reg. 08676338). All information that appears on this website is intended for information purposes only and should be used to supplement, not replace, your relationship with your local healthcare professionals. You should consult your doctor if you think you may have a health problem or before you start taking a new medicine. Please ensure you always read the information leaflets supplied with any medicinal products.For more information see our policies and terms and conditions at the bottom of every page. © 2014 ABSM Healthcare Ltd. All rights reserved.
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