Paludrine/Avloclor Travel Pack 250mg/100mg Tablets
Avloclor tablets contain the active ingredient chloroquine and Pauldrine tabelts contain proguanil. They work to kill any malaria parasites present in your blood following a mosquito bite. Paludrine/Avloclor are an effective combination to prevent malaria in certain areas where resistance is not present. The Paludrine/Avloclor travel pack has the benefit of being very cost effective and has fewer incidences of side effects than other antimalarials.
Malaria can take up to a year to develop after you have been bitten. If you experience symptoms including headaches, night sweats and abdominal pain any time during your trip or up to one year afterwards you must see a doctor as soon as possible.
In areas of possible chloroquine resistance, it is combined with proguanil to ensure you are adequately protected during your travels. Choloroquine is taken as a single dose of 2 tablets once weekly and proguanil is taken as 2 tablets daily. Both tablets are started 1 week before travel and continued for 4 weeks after returning.
To find out if Paludrine/Avloclor is suitable for your trip, check the Fit For Travel website for up to date travel health information.
Although Paludrine & Avloclor help to prevent you contracting malaria, it is also important to prevent mosquito bites to reduce your risk. For more information about malaria and bite prevention, see our Malaria Prevention page.
Please read the Patient Information Leaflet for side effects and additional information.
Pharmacist Tip: Chloroquine/proguanil is suitable during pregnancy and breastfeeding, however it should not be taken if you suffer with epilepsy or psoriasis. The tablets should be taken with or after food to help reduce side effects.
Paludrine/Avloclor should be taken as follows for the greatest reduction in malaria risk:
- You should take two Avloclor tablets every week on the same day each week.
- You should take two Paludrine tablets every day at roughly the same time each day.
- Paludrine/Avloclor needs to be taken one week before entering an area where malaria is present and continued until four weeks after leaving the malaria area.
- You should take Paludrine/Avloclor with or after food.
- Paludrine/Avloclor remains effective with a moderate alcohol intake.
- Each Paludrine tablet contains 100 mg of proguanil hydrochloride (the active ingredient).
- The other ingredients are calcium carbonate, gelatin, magnesium stearate and maize starch.
- Each Avloclor tablet contains 250 mg of chloroquine phosphate (equivalent to 155 mg of chloroquine base).
- The other ingredients are magnesium stearate and maize starch.
If you do experience side effects from Avloclor they may include nausea, diarrhoea, headache, rashes, skin itch, blurred vision, hair loss, dizziness, mood change, sun sensitivity or seizures. As such you should not take Avloclor if you or a close relative suffers with epilepsy. Avloclor can also worsen psoriasis; people who suffer with psoriasis should avoid taking Avloclor if possible. The side effects of Paludrine can include anorexia, nausea, diarrhoea, constipation, skin itch and mouth ulcers. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.
If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.
Paludrine can prolong bleeding time if taken with anticoagulants such as warfarin. If you take an anticoagulant you should speak to your GP before taking Paludrine/Avloclor. Please read the Patient Information Leaflet enclosed with your medicines for further information.
You should try to avoid taking Avloclor around the same time as indigestion or heartburn remedies containing high levels of calcium, iron or magnesium as this can reduce its effectiveness.
Paludrine/Avloclor is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods.
It is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave.
The Paludrine/Avloclor Travel Pack should not be taken without checking with your GP if you take any of the following medicines:
- Praziquantel (used to treat infections of the bowel and bladder caused by parasites).
- Ciclosporin (mainly used by transplant patients but also used to treat rheumatoid arthritis and psoriasis).
- Anti-convulsant medicines (used to prevent convulsions or fits).
- Digoxin (used to treat heart problems).
- Warfarin or other medicines used to prevent blood clots. Paludrine may increase the effect of these medicines.
- Other medicines used to prevent malaria, such as mefloquine. There is a risk of convulsions or fits when these medicines are taken at the same time as Avloclor.
- Cimetidine (used to treat stomach problems). This medicine affects how Avloclor is broken down by your body and may affect the amount of Avloclor in your blood.
- Medicines like kaolin (used for diarrhoea) which are called ‘adsorbents’.
- Antacids (aluminium, calcium and magnesium salts that are used to treat heartburn or indigestion).
You should not take Paludrine/Avloclor if you suffer with:
- Problems with your kidenys or liver
- Myasthenia gravis
- Glucose-6-phosphate dehydrogenase deficiency
All our orders are sent out using Royal Mail. Tracking is available on all orders.
We always aim to dispatch all orders within 24 hours of them being received, if we are unable to meet this
high standard for whatever reason we will always contact you to advise you of the delay.
We offer free UK standard delivery on orders over £40.
The following delivery options are available:
- Standard Delivery - 2/3 day delivery - £2.95
- Express Delivery - 1/2 day delivery - £4.45
- Special Delivery (Guaranteed before 1pm) - £8.95
- Saturday Guaranteed before 1pm - £10.45
The cut-off for same day dispatch of orders is 4pm. Orders processed after this time will be dispatched the following working day. Orders are dispatched Monday - Friday. Orders will not be processed on weekends or bank holidays.
We ensure all deliveries are in plain packaging for discreet delivery of your medicines and pharmacy goods.
Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt.
Delivery is free for all NHS prescriptions.
Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering.
We are currently unable to ship orders outside of the UK.