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Synphase Tablets

Synphase Tablets

Pack Size: 3 x 21 tablets
Our Price: £21.99
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Age: 18 years + Pregnancy: Not suitable Breastfeeding: Not suitable

Buy repeat supplies of Synphase tablets online with a quick, easy, free online consultation. Phasic 21-day contraceptive pills, like Synphase, contain a combination of the hormones oestrogens and progestogens. They help to make it harder for the sperm to penetrate the womb and to reduce the chance of a fertilised egg implanting in the womb. If taken correctly they are over 99% successful at preventing pregnancy.

Pharmacist Tip

Unless you have been told otherwise by your GP, it is usually fine to start a new pack of pills straight after you have finished your last one, without a break, to delay your period. You should not run more than two packs together without advice from your doctor.

Synphase is a phasic 21-day contraceptive pill containing the active ingredients ethinylestradiol and norethisterone. It helps to make it harder for the sperm to penetrate the womb and to reduce the chance of a fertilised egg implanting in the womb. It is over 99% effective at preventing pregnancy if taken correctly.

Synphase are oral contraceptive tablets manufactured by Pharmacia. They contain the active ingredients Ethinylestradiol and Norethisterone. These ingredients are synthetic versions of Oestrogen and Progesterone, which are female sex hormones naturally produced by women. Oral contraceptives are more commonly referred to as ‘the pill’. Synphase is classed as a prescription-only-medicine (POM) and is available in packs of 21 tablets. Synphase is known as a triphasic pill, each pack containing three variations of the Synphase tablet. Each variation contains a slightly different dose of the active ingredients:

  • 7 blue tablets, which contain Ethinylestradiol 35mcg and Norethisterone 500mcg
  • 9 white tablets, which contain Ethinylestradiol 35mcg and Norethisterone 1mg
  • 5 blue tablets, which contain Ethinylestradiol 35mcg and Norethisterone 500mcg

It is important to take Synphase in the order specified on the numbered blister, starting with the blue tablet marked ‘1’. Take one tablet every day, following the numbers in sequence. After 21 days you then take a seven day break from taking Synphase. This will allow your hormone levels to drop, resulting in a withdrawal bleed that is similar to your normal period. Providing the tablets have been taken correctly, you will still be protected during the tablet free week. After this seven day break you then start your next pack of Synphase tablets, starting again with the blue tablet marked ‘1’.

During a natural menstrual cycle, the levels of sex hormones fluctuate throughout the month. It is these fluctuations that causes the release of eggs from the ovaries and prepares the womb’s lining for a potential pregnancy. If at the end of this cycle no egg has been fertilised, the hormone levels drop causing the lining of the womb to shed as a monthly period.

Synphase is known as a combined oral contraceptive, which relates to its two synthetic hormones. Combined oral contraceptives work by over-riding the natural female menstrual cycle. These synthetic hormones essentially trick the body into thinking that ovulation has already occurred. This prevents an egg from being released from the ovaries each month. Synphase tablets also increases the thickness of the natural mucus at the neck of the womb. This makes it more difficult for sperm to penetrate the womb and reach a viable egg. It also alters the consistency of the womb’s lining (endometrium). This change in the endometrium decreases the chances of a fertilised egg being implanted there.

Please read the Patient Information Leaflet for side effects and additional information.

Pharmacist Tip: Synphase should be taken regularly at roughly the same time every day with a 7-day pill-free break after each pack. If you miss one pill anywhere in your pack, take it as soon as you remember even if it means taking two pills in a day. You should continue taking your pills as normal and you will not need additional contraception. If you miss more than one pill you will lose your contraceptive cover and extra contraception will be required for at least 7 days.

  • Start Synphase with the first pill of the first colour.
  • Continue taking one pill at the same time each day, working your way around the pack until it is finished.
  • You should then have a 7-day break when you will have your period.
  • You should then start your new pack of pills on the 8th day (this will be the same day that you started your last new pack).

Missed Pill Advice

According to NHS Choices; if you have missed one pill, anywhere in the pack:

  • take the last pill you missed now, even if it means taking two pills in one day
  • continue taking the rest of the pack as usual
  • you don’t need to use additional contraception, such as condoms
  • take your seven day pill-free break as normal

However, if you have missed two or more pills (you are taking your pill more than 48 hours late) anywhere in the pack:

  • take the last pill you missed now, even if it means taking two pills in one day
  • leave any earlier missed pills
  • continue taking the rest of the pack as usual and use an extra method of contraception for the next seven days
  • you may need emergency contraception
  • you may need to start the next pack of pills without a break

 Each Synphase contraceptive pill contains a slightly different dose of the active ingredients depending on the colour:

  • 7 blue tablets, which contain Ethinylestradiol 35mcg and Norethisterone 500mcg
  • 9 white tablets, which contain Ethinylestradiol 35mcg and Norethisterone 1mg
  • 5 blue tablets, which contain Ethinylestradiol 35mcg and Norethisterone 500mcg

The other ingredients in each tablet are maize starch, polyvidone, lactose, magnesium stearate and colouring E132 (in the blue pills only).

If you do experience side effects from your contraceptive pill they may include headaches, nausea, sickness, breast tenderness, and mood swings. These should normally only last for the first few months if they are experienced. If they last longer than this please consult your doctor.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Tell your doctor or call an ambulance immediately if you experience any of the following symptoms of an allergic reaction after taking this medicine. Although they are rare, the symptoms can be severe and you may need urgent medical attention or hospitalisation.

  • Sudden wheeziness, difficulty in breathing, chest pain, fever, sudden swellings, rash or itching (especially affecting the whole body).

Stop taking Synphase and contact your doctor straight away if you notice any of the following serious side effects. These may be signs of thrombosis (a blood clot):

  • You are coughing up blood.
  • You have swelling or tenderness in your stomach.
  • You have a sudden sharp or severe pain in your chest.
  • You suddenly become short of breath or find breathing is painful.
  • You have painful or inflamed veins in your legs.
  • You have a first attack of migraine (a bad headache with sickness).
  • You have migraines which get worse, especially if your sight is affected, you see flashing lights, your limbs feel weak, you lose the sensation or feel a different sensation in your limbs, or you have a fit.
  • You have sudden and unusual severe headaches.
  • You experience dizziness or you faint.
  • You develop a problem with your sight or speech.

The contraceptive pill should not cause a harmful interaction with any of your other current medicines.  Some medicines can reduce the effectiveness of the contraceptive pill including some antibiotics; tsee below for a full list of interacting medicines. Please read the Patient Information Leaflet enclosed with your medicines for a full list of medicines that may affect your contraceptive pill.

Taking your pill whilst suffering with sickness and/or diarrhoea

Synphase may not work if you have a stomach upset or you are sick, or if you have severe diarrhoea. You should carry on taking the tablets as normal, but use a condom while you are ill and for the next seven days. If these seven days run beyond the end of the blister strip, start the next pack without a break.

Medical check-ups while taking Synphase

It is important to get regular check-ups from your GP or practice nurse whilst you are taking Synphase. Your blood pressure will be checked before you start Synphase and then at regular intervals whilst you are on Synphase. You may be required to have an examination of your breasts, abdomen and pelvis including taking a cervical smear test at regular intervals, if this is considered necessary by the doctor. We are unable to provide supplies of contraceptive pills if the regular check-ups are not up to date.

Medicines that reduce the effectiveness of the contraceptive pill

The following medicines may stop Synphase from working properly (the condition they treat being shown in brackets):

  • The herbal remedy St John’s wort – Latin name Hypericum perforatum (depression)
  • Carbamazepine (epilepsy)
  • Oxacarbazepine (epilepsy)
  • Phenytoin (epilepsy)
  • Phenobarbital (sleeplessness, anxiety, epilepsy)
  • Primidone (epilepsy)
  • Topiramate (epilepsy)
  • Nelfinavir (HIV – Human Immunodeficiency Virus - infection)
  • Nevirapine (HIV infection and AIDS)
  • Ritonavir (HIV infection and AIDS)
  • Rifabutin (bacterial infection)
  • Rifampicin (bacterial infection)
  • Griseofulvin (fungal infection)
  • Modafinil (narcolepsy i.e. daytime sleepiness)

Taking the contraceptive pill may cause small increases in the likliness of some medical conditions such as blood clots, breast cancer, cervical cancer, and liver cancer. Your GP should have discussed these with you before you started taking Synphase. The risk depends on the length of time you take Synphase, other medicines you take and your current state of health.

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The Independent Pharmacy is an online pharmacy and online doctor service is owned and operated by ABSM Healthcare Ltd (Company Reg. 08515600) and Red Label Medical Ltd (Company Reg. 08676338). All information that appears on this website is intended for information purposes only and should be used to supplement, not replace, your relationship with your local healthcare professionals. You should consult your doctor if you think you may have a health problem or before you start taking a new medicine. Please ensure you always read the information leaflets supplied with any medicinal products.For more information see our policies and terms and conditions at the bottom of every page. © 2014 ABSM Healthcare Ltd. All rights reserved.
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