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Tetralysal 300 (Lymecycline) Capsules

Tetralysal 300 (Lymecycline) Capsules

Pack Size: 28 capsules
RRP: £18.00
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Age: 18 years + Pregnancy: Not suitable Breastfeeding: Not suitable

If you are suffering with acne and have found over-the-counter treatments to be ineffective, Tetralysal 300 (lymecycline) capsules are available to buy from our Online Doctor following a free consultation. Tetralysal are some of the most popular acne antibiotics and are available to buy online with fast, discreet delivery.

Pharmacist Tip

Wash your face using a mild soap or cleanser with warm water. Do not wash your skin more than twice daily. This can irritate your skin, remove essential oils and make your symptoms worse. 

Tetralysal 300 capsules are available to buy from The Independent Pharmacy Online Doctor service, following a free consultation, to help to treat acne. To find out more about acne and see all the available treatments, see our Online Doctor Acne page.

Tetralysal 300 is an oral medication used to treat acne. Acne symptoms will present as blackheads and whiteheads, which are often referred to as spots or pimples. Tetralysal is often prescribed when over-the-counter acne treatments have proven ineffective or where moderately severe acne is present that requires prescription treatment.

Tetralysal 300 capsules are manufactured by Galderma. The active ingredient, Lymecycline belongs to a group of medicines called tetracycline antibiotics. Lymecycline is a broad spectrum antibiotic that’s effective against a wide variety of bacteria. Tetralysal is predominantly prescribed for the treatment of acne. However, your GP may also use it to treat other bacterial infections, such as chest infections, urine infections, skin infections and mouth infections. 

Tetralysal 300 hard capsules contain the active ingredient Lymecycline, an antibiotic. For treating acne, Tetralysal works to inhibit the bacteria associated with causing acne, Propionibacterium. This common type of bacteria feeds on sebum produced by the sebaceous glands in the skin. This causes propionibacterium to produce waste products and fatty acids that can irritate the sebaceous glands. This irritation will cause the sebaceous glands to become inflamed, causing spots to develop. Lymecycline interferes with this bacteria’s ability to produce proteins that are essential for their production. This action stops the spread of the infection, reducing the inflammation of the sebaceous glands and allowing the skin to heal. Any remaining bacteria are killed by the immune system or eventually die.

Tetralysal 300 hard capsules are suitable for treating mild to moderate acne where there is an active infection and visible inflammation. The duration of treatment will depend on how quickly your condition improves. For acne, Lymecycline will normally be taken for at least eight weeks. If you have seen no improvement in your acne after 3 months you may wish to discontinue Tetralysal and try a different acne treatment.

Tetralysal capsules can also be used with other topical acne treatments such as creams containing benzoyl peroxide (Epiduo, Quinoderm & Panoxyl) or azelaic acid (Skinoren) that help to dry out the skin, reducing the amount of sebum present.

Tetralysal capsules do not contain penicillin and are not related to penicillin.   

  • You should take one Tetralysal capsule daily, preferably in the morning.

  • Tetralysal capsules should always be taken with a full glass of water.

  • For treating acne, you will normally need to take Tetralysal for at least 8 weeks. Treatment should be assessed after 3 months to determine whether it has been effective. If your treatment has been effective, you can continue to take Tetralysal for another 3 months where you should see further improvement. If there has been no improvement in your acne, you should stop taking Tetralysal and consider a different acne treatment.

Each Tetralysal 300mg capsule contains lymecycline 408mg.

Each capsule also contains gelatin, titanium dioxide (E171), erythrosine (E127), quinoline yellow (E104) and indigotine (E132). 

Like all medicines, Tetralysal capsules can cause side effects including nausea & vomiting, diarrhoea, stomach ache, visual disturbances and dizziness. In rare cases Tetralysal can also cause fungal infections such as thrush, skin reactions, photosensitivity, colitis and pancreatitis. 

If you experience any adverse effects from taking Tetralysal it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Tetralysal can interact with certain medicines. These include medicines used to thin your blood (e.g. warfarin) & diuretics (used to treat kidney disease, heart disease or high blood pressure). It can also interact with other acne antibiotic medicines. If any of the above interactions apply to you please notify us immediately.

Do not take following medicines at the same time as Tetralysal as they can affect how well your acne medicine works. Wait at least two hours after taking Tetralysal before you take these types of products:

  • Indigestion remedies

  • Ulcer healing drugs

  • Quinapril (for high blood pressure)

  • Supplements containing calcium, aluminium, magnesium, zinc or iron.

You should contact your doctor immediately if you experience any of the following symptoms whilst taking Tetralysal:

  • Severe, persistent headache
  • Double or blurred vision
  • Yellowing or the skin or eyes (jaundice)
  • Unexplained bruising
  • Persistent sore throat
  • Fever 
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All our orders are sent out using Royal Mail. Tracking is available on all orders. We always aim to dispatch all orders within 24 hours of them being received, if we are unable to meet this high standard for whatever reason we will always contact you to advise you of the delay.

We offer free UK standard delivery on orders over £40.

The following delivery options are available:

  • Standard Delivery - 2/3 day delivery - £2.95
  • Express Delivery - 1/2 day delivery - £4.45
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

The cut-off for same day dispatch of orders is 4pm. Orders processed after this time will be dispatched the following working day. Orders are dispatched Monday - Friday. Orders will not be processed on weekends or bank holidays.

We ensure all deliveries are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 


We are currently unable to ship orders outside of the UK.

Tetralysal (Lymecycline) FAQ's

What does Tetralysal contain? 

Tetralysal capsules contain lymecycline 408mg per capsule. For a full list of ingredients see the 'Ingredients' tab. Lymecycline is a tetracycline antibiotic that helps to kill the bacteria that overgrow on the skin and contribute to acne.


How do I take Tetralysal/lymecycline? 

In adults and children 18 years and over, the dose of Tetralysal is 1 capsule daily, usually in the morning. You should not take more than one Tetralysal capsule in a 24-hour period.


Why can I only buy three months of Tetralysal online at one time?

Tetralysal is an prescription-only antibiotic. For that reason, to ensure the safety of our patients and the legal operating of our pharmacy, we only supply a maximum of 3 months treatment at one time. Tetralysal treatment is normally judged for effectiveness after 3 months. This means that if you do not find Tetralysal as effective as you would like, you are not stuck with an excess of medication. If you are happy with the results you can log in and re-order another supply.


Should I take Tetralysal with food?

There are no specific instructions on whether you need to take Tetralysal with food or not, however it should be taken with plenty of water.

Is Tetralysal available for next day delivery?

Yes, we understand that sometimes you want to get your treatment as soon as possible. If ordered before 4pm, Tetralysal capsules are available for next day delivery.

Is it safe to buy Tetralysal (Lymecycline) capsules online?

Yes, as long as you are buying from a website that is a legally operating and regulated pharmacy it is perfectly safe to buy Tetralysal online. The Independent Pharmacy is an NHS Online Pharmacy based in Bristol and has all the necessary regulation to be able to safely provide convenient access to genuine prescription treatments through our Online Pharmacy & Online Doctor. We only provide genuine branded Tetralysal capsules sourced from reputable UK wholesalers.

How do I buy Tetralysal online?

It simple! Just select 'Start Consultation' above, you will need to fill in a simple health questionnaire so our GPs & Pharmacists can ensure it is safe for us to supply your Tetralysal to you. It all takes around 3 minutes and your treatment can be delivered to your door.

What are the advantages of buying Tetralysal online?

There are many advantages to buying Tetralysal capsules online, some include:

  • It's quick & easy - there is no need to spend time at the doctor or pharmacy.
  • Fast delivery - We offer same day dispatch before 4pm and fast delivery to your address of choice with Royal Mail.
  • Great prices - we are able to offer very competitive prices and we guarantee to beat any other Online Doctor service.
  • Tons of information - we provide all the information you could need on Tetralysal/lymecycline and other acne treatments, in easy to digest formats, at a time to suit you.


How long does it take for Tetralysal (Lymecycline) to work?

Tetralysal is normally taken for a minimum of 8 weeks to treat acne. After 8 weeks you should be able to tell if it has helped to improve your skin and then make a decision as to whether they should be continued or not. Short courses of Tetralysal for fewer than 8 weeks are usually less effective and is unlikely to give you an accurate picture of whether it will be an effective treatment to clear up your acne.


How does Tetralysal/Lymecycline work?

Lymecycline is an antibiotic. Acne is often caused by the bacteria that naturally live on your skin overgrowing and creating by-products that build up and block pores. These blocked pores over time turn into spots and hence acne. Lymecycline helps to keep the levels of bacteria living on your skin under control which helps to unclog your pores and clear up the symptoms of acne.


Can I use other acne treatments with Tetralysal/lymecycline?

You can combine Tetralysal with creams such as containing benzoyl peroxide (Epiduo, Quinoderm & Panoxyl) or azelaic acid (Skinoren). Tetralysal should not be taken with any other products containing antibiotics such as erythromcyin, tetracycline or minocycline. Generally Tetralysal is not used with any other acne antibitoic treatment as they have a similar method of action and usually do not provide any additional benefit. Simultaneous use of multiple acne antibiotics may also increase the risk of experiencing side effects. 


How severe should my acne be to take Tetralysal?

Tetralysal should be used to treat moderate to severe acne on the face, neck, shoulders or back. Moderate acne is defined by NHS Choices as where there are multiple papules and pustules (red spots and whiteheads) that are mostly confined to the face. If this describes your acne, or it is more severe, Lymecycline may be a suitable treatment for your acne.


Does Tetralysal affect the contraceptive pill?

Tetralysal may affect the contraceptive pill making it less effective. You may wish to consider using additional methods of contraception, such as condoms, whilst taking Tetralysal.


Does drinking alcohol affect Lymecycline?

Tetralysal capsules should be taken once daily in the morning. They are unlikely to be affected by alcohol consumed later in the day.


What if Tetralysal doesn't work?

If lymecycline treatment is ineffective on your acne, there are many other options for you to try. You may wish to try a different antibiotic treatment such as Dalacin T or Zineryt, or alternatively a different method with topical treatments such as Differin or Skinoren. Different people find that their acne responds to different treatment depending on their skin type, what causes their acne and any other skin conditions they may also suffer with. It is therefore important to try a range of treatments and give them time to have an effect to allow you to find a suitable and effective treatment for your acne.


Should I stop taking Lymecycline as soon as my acne clears up?

If you find treatment with Tetralysal successful and your acne improves, you should continue taking Tetralysal for a few months before stopping your treatment. This will ensure that any remaining excess bacteria on your skin are removedand give you the best chance of keep your skin clear of spots by cleansing alone.


If I stop taking Tetralysal will my acne return?

It is possible for Tetralysal to reduce your acne to levels where it can be controlled by cleansing alone in some cases whereas for other people they may find that their acne returns after a period of time. It is generally not advised to take Tetralysal for very long periods, if your acne has cleared up you should take a break from the capsules after a few months to see if they are still required and to give yourself a break from the constantly taking the drug.


Is Tetralysal only effective for acne on the face?

Acne is most common on the face although it does also occur on the neck, shoulders and back. As Tetralysal (lymecycline) is taken orally and is absorbed into your system, it is effective wherever there is an overgrowth of bacteria causing acne, whether it is you face, neck, shoulders or back.


I can't swallow capsules, can I open the capsules up?

Tetralysal capulses should be swallowed whole with plenty of water. Opening the capsules may cause them to be ineffective due to the drug being exposed to the content of the stomach.


I'm under 18, can I take Tetralysal?

Tetralysal is licenced for use in those aged 12 years or over. The Independent Pharmacy Online Doctor service is able to prescibe Tetralysal to people aged 18 years and over for the treatment of acne. If you are aged under 18, you will need to see your GP for Tetralysal to ensure it is appropriate for you and your condition.


It cleared up my acne but it has now come back, can I use it again?

If you stop taking Tetralysal and your acne comes back, you may restart treatment at any point. If your condition improves then you should continue with lymecycline treatment however, if it is less effective during subsequent rounds of treatment you may wish to try a different acne treatment.


Is there anything else I can do whilst I am taking Tetralysal to help my acne?

As well as using antibiotic acne treatment such as Tetralysal (lymecycline), you should also get in to the habit of cleansing the affected areas regularly. You should wash them twice daily with warm, not hot, water using a mild cleansing agent. When washing, ensure you do not scrub the area too hard so as to irritate the skin as this can make acne worse. If you use moisturisers or make-up on the affected area, try to ensure they are non-comedogenic (oil-free) so that they do not contribute to your acne.


Where can I find out more information about acne?

The British Association of Dermatologists provide some great information for beginners on acne and it's treatment. The Acne Academy is a great charity offering help, support and information for acne suffers as well as busting a few acne related myths!

Compare Different Acne Treatments

Drug name Type of Acne Treated How to use it Pack Size


1 Pack Treatment Price

Click to Start Consultation/Buy

2 Packs of treatment

Panoxyl Aquagel 10 Mild Acne Only Usually applied to the affected areas 20 minutes after washing with a mild soap or cleanser 30g            
Quinoderm 10 Cream Mild Acne Only Usually applied to the affected areas 20 minutes after washing with a mild soap or cleanser 30g            
Quinoderm 5 Cream Mild Acne Only Usually applied to the affected areas 20 minutes after washing with a mild soap or cleanser 30g            
Skinoren Cream Mild To Moderate Acne

Skinoren cream should be rubbed into the affected areas twice daily, after washing.

Those with sensitive skin may wish to apply Skinoren cream once daily in the evening for the first week of treatment.

30g 14.50 Saving £1.45 25.00  Saving £6.90        
Differin Cream Mild To Moderate Acne Cream 45g            
Epiduo Gel Mild To Moderate Acne Aqueous Gel 45g            
Minocycline MR Capsules 100mg Mild To Moderate Acne Modified Release Capsules              
Oxytetracycline Tablets 250mg Mild To Moderate Acne                
Tetralysal 300 (Lymecycline) Capsules Mild To Moderate Acne                

The Independent Pharmacy is an online pharmacy and online doctor service is owned and operated by ABSM Healthcare Ltd (Company Reg. 08515600) and Red Label Medical Ltd (Company Reg. 08676338). All information that appears on this website is intended for information purposes only and should be used to supplement, not replace, your relationship with your local healthcare professionals. You should consult your doctor if you think you may have a health problem or before you start taking a new medicine. Please ensure you always read the information leaflets supplied with any medicinal products.For more information see our policies and terms and conditions at the bottom of every page. © 2014 ABSM Healthcare Ltd. All rights reserved.
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