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Trimethoprim 200mg Tablets

Trimethoprim 200mg Tablets

Pack Size: 6 tablets
RRP: £40.00
Saving: £22.51
Our Price: £17.49
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Age: 18 years + Pregnancy: Not suitable Breastfeeding: Not suitable

Trimethoprim is an antibiotic that helps to kill the bacteria causing cystitis. It is the first line treatment for simple cystitis caused by the most common bacterial infections.

Trimthoprim will clear up most simple cases of cystitis caused by the most common bacteria, however because many different bacteria can cause urinary tract infections it is important that if your symptoms do not improve or worsen that you see your GP.

Pharmacist Tip
  • Drink plenty of fluids. It is important to drink plenty of fluids when you are suffering with cystitis to help flush the bacteria through your system. It is also important to keep hydrated to prevent cystitis recurring
  • Take sodium citrate or potassium citrate sachets. If you are suffering with cystitis you can also take sodium citrate sachets to provide immediate relief for the burning sensation when you urinate.

Trimethoprim 200mg tablets are available from The Independent Pharmacy Online Doctor service, following a free consultation, for the treatment of simple cystitis. To find out more about cystitis and see all the available treatments, see our Online Doctor Cystitis page.

Trimethoprim 200mg tablets are antibiotics that are mainly used to treat urinary tract infections (also known as UTI’s, cystitis, bladder infections or water infections).  Trimethoprim is effective in around 9 out of 10 simple cystitis cases and will help to cure the infection in a couple of days. For most uncomplicated cases of cystitis, Trimethoprim 200mg tablets should be taken twice daily, one tablet every 12 hours until the prescribed course is complete. You should start taking Trimethoprim as soon as you feel the onset of cystitis symptoms.

Most cases of cystitis or UTIs are caused by E.coli, which originates in your gut. Trimethoprim does not kill E.coli, however it stops bacterial DNA synthesis meaning it cannot replicate. This allows your immune system to destroy the infecting bacteria until they are gone and your infection is resolved.

Trimethoprim is not affected by food or alcohol so there is no need to alter your diet whilst taking it. Trimethoprim can be safely taken with other over-the-counter cystitis treatments, such as Cymalon & Cystopurin, which help to reduce the acidity of the urine. You can also take simple painkillers such as paracetamol, alongside Trimethoprim with no problems.

Your symptoms will normally improve within 24 – 48 hours of taking Trimethoprim 200mg tablets. You should always complete the course, even if you feel better. If your prescribed Trimethoprim 200mg tablets have not improved your symptoms after the three-day course, you should see your GP. This may suggest that your UTI is resistant to Trimethoprim or that your symptoms are caused by something other than a bacterial infection, which requires investigation.

Trimethoprim can also be used to prevent cystitis at a dose of 100mg at night. You would need to see your GP to discuss recurrent bouts of cystitis to see if Trimethoprim 100mg tablets are suitable.

  • Take one Trimethoprim 200mg tablet twice daily, roughly 12 hours apart.
  • You should always continue the course until it is complete unless otherwise directed by a doctor.
  • You should start taking Trimethoprim 200mg tablets as soon as you recognize the symptoms from cystitis that has previously been diagnosed by your GP.
  • You should see your GP if no improvement in your symptoms once the course is complete.

If you notice blood in your urine, or suffer with fever, chills, back pain, or vomiting your infection may be more serious and you should see your GP as soon as possible.

If you find that you have suffered with cystitis more than 3 times in one year you should see your GP for an investigation into the cause of your recurrent infections.


Your treatment contains 200mg of Trimethoprim per tablet.

It is possible that you may be allergic to Trimethoprim. If you know you are allergic to Trimethoprim or have suffered a reaction previously do not take Trimethprim and discuss alternatives with your GP.

Trimthoprim has a small risk of nausea, vomiting, diarrhoea, and skin rash as with all medicines. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking Trimethoprim 200mg tablets it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Trimethoprim 200mg tablets should not cause a harmful interaction with any of your other current medicines. It should not be taken if you currently take azathioprine, ciclosporin, dapsone, digoxin, eplerenone, mercaptopurine, methotrexate, phenytoin, procainamide, pyrimethamine, repaglinide, rifampicin, or warfarin. This was checked during your online consultation. Please read the Patient Information Leaflet enclosed with your medicines for further information.

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All our orders are sent out using Royal Mail. Tracking is available on all orders. We always aim to dispatch all orders within 24 hours of them being received, if we are unable to meet this high standard for whatever reason we will always contact you to advise you of the delay.

We offer free UK standard delivery on orders over £40.

The following delivery options are available:

  • Standard Delivery - 2/3 day delivery - £2.95
  • Express Delivery - 1/2 day delivery - £4.45
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

The cut-off for same day dispatch of orders is 4pm. Orders processed after this time will be dispatched the following working day. Orders are dispatched Monday - Friday. Orders will not be processed on weekends or bank holidays.

We ensure all deliveries are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 


We are currently unable to ship orders outside of the UK.

Trimethoprim FAQ's


  1. What is Trimethoprim and what does it contain?
  2. How does it work?
  3. What’s the difference between Trimethoprim and Cymalon, Cystopurin and other cystitis products?
  4. How do I take it?
  5. How long will it take to work?
  6. What’s the difference between Trimethoprim and other antibiotics?
  7. Is it safe to use Trimethoprim continuously?
  8. How effective is it?
  9. What are the side effects of Trimethoprim?
  10. Forgotten to take a tablet- Here’s what to do?
  11. Trimethoprim should be used with caution in these patients.
  12. Trimethoprim and other medication?
  13. Alcohol and Trimethoprim?
  14. Why can I only buy one course of Trimethoprim online at one time?
  15. Should I take Trimethoprim with food?
  16. Is Trimethoprim available for next day delivery?
  17. Is it safe to buy Trimethoprim tablets online?
  18. How do I buy Trimethoprim online? 

  19. What are the advantages of buying Trimethoprim online? 

  20. Will it stop my pill from working?
  21. What happens if it doesn’t work?
  22. Can you take painkillers whilst being treated with trimethoprim?
  23. Can you treat cystitis in men online?
  24. Can I have a course of antibiotics as a back up?
  25. Will Trimethoprim give you thrush?
  26. Does cranberry juice help treat cystitis?



1.What is Trimethoprim and what does it contain? 

Trimethoprim tablets contain trimethoprim 200mg per tablet.

It is an antibiotic that helps to kill the bacteria that cause a number of infections including cystitis (also known as a water infection) or urinary tract infections. It is only available on prescription after a consultation with a Doctor. This can be face-to-face or online.

It is the antibiotic of choice for Doctors and is effective in 90% of urine infections.


2.How does it work?

Bacteria cells need to produce their own DNA when they multiply. Trimethoprim blocks this process and stops them reproducing. The remaining bacterial cells are killed of by the body’s immune system.

As 80% of trimethoprim is excreted in the urine, this makes it very useful for treating bladder and urine infections, as its in high concentration where it is needed.


3.What’s the difference between Trimethoprim and Cymalon, Cystopurin and other products you can buy over the counter?

Trimethoprim is an antibiotic that kills the bacteria that is causing the infection.

Other over the counter remedies like Cymalon, Cystopurin and Canesten Oasis, neutralize the acidity of the urine. It helps to reduce the burning, pain on urination and changes the acidic environment of the bladder making it harder for the bacteria to survive.


Trimethoprim and Over the Counter remedies can be taken together. Cymalon and other over the counter remedies will help to make the urine less acidic and ease discomfort whilst the antibiotics have a chance to take effect.

4.How do I take it?

In adults and children 18 years and over, the dose of Trimethoprim is 1 tablet twice daily, in the morning and evening.

You should not take more than two Trimethoprim tablets in a 24-hour period.

Finish the course of antibiotics- Take all the tablets even if you start to feel well


5.How long will it take to work?

Symptoms should start to ease within 24 hours and should have gone after 3 days of treatment. If you still have symptoms after this time or they become worse then you need to see a doctor face to face.


6.What’s the difference between Trimethoprim and other antibiotics?

Not all antibiotics can be used to treat the same infection. They work in different ways and some work on certain bacteria whilst others don’t.

Trimethoprim is excreted mostly in the urine which means its in high concentration where it is needed and is very effective against bacteria that cause urine infections.


7.Is it safe to use Trimethoprim continuously?

If you are getting recurrent urine infections it is worth visiting your doctor so they can send a urine sample away for analysis and ensure there is no underlying cause for concern. For this reason we do not recommend you use trimethoprim regularly without speaking to your doctor.


8.How effective is it?

Trimethoprim is the number one choice for Doctors for treating of Urinary Tract Infections and is effective 90% of the time.


9.What are the side effects of Trimethoprim?

As most courses of treatment are short (ranging from 3-5 days), most women do not suffer form any side effects at all. The most common unwanted effects are gastro intestinal, like diarrhoea, nausea, vomiting and a rash.

If a rash occurs then stop taking the tablets and see your doctor.


10.Forgotten to take a tablet- Here’s what to do?

Take one when you remember or if more than 24 hours has past take the next tablet at the right time. Do not double up and take twice the dose.

Its important to take the tablets regularly and as the course is only for 3 days, it missing tablets could prolong the infection for longer.

Taking first thing in the morning and last thing at night can help to remember or setting an alarm on your phone can also act as a prompt.


11.Trimethoprim should be used with caution in these patients.

You should not take trimethoprim if you have

  • An allergy to trimethoprim
  • Kidney problems
  • Pregnant
  • Blood disorders


The following indicate that the infection is no longer located in just in the bladder and may have progressed. If you have nay of the following you should see a doctor straight away

  • Back pain – this may show the infection has now spread to the kidney(s)
  • Fever, high temperature, shivering, hot and cold sensations
  • Nausea, sickness and loss of appetite
  • Flu like symptoms 


12.Trimethoprim and other medication?

If you are taking or have recently taken any of the following then you need to tel us in your consultation before you take trimethoprim tablets.

  • Any other antibiotics
  • Blood thinners like warfarin
  • Medicines to prevent organ transplantation rejection like ciclosporin
  • Heart medication like digoxin
  • Epilepsy medication like phenytoin
  • Malaria treatments like pyrimethamine


13.Alcohol and Trimethoprim?

Unlike some antibiotics which can cause you to be sick and feel nausesous

Trimethoprim is not affected by alcohol.

It is important to remember that trimethoprim is a diuretic and it will flush the antibiotic out of your system quicker than usual making the treatment less likely to be effective.. It best to drink in moderation.


14.Why can I only buy one course of Trimethoprim online at one time?

Trimethoprim is an prescription-only antibiotic. For that reason, to ensure the safety of our patients and the legal operating of our pharmacy, we only supply a maximum of one course of treatment at one time. In addition, due to the need for a physical check-up if you are suffering with regular attacks of cystitis and the risk of bacterial resistance to antibiotics over time, our online prescribers will judge each case for the consultation notes and offer treatment and/or advice as appropriate.


15.Should I take Trimethoprim with food?

There are no specific instructions on whether you need to take Trimethoprim with food or not, however it should be taken with plenty of water.


16.Is Trimethoprim available for next day delivery?

Yes, we understand that sometimes you want to get your treatment as soon as possible. If ordered before 4pm, Trimethoprim tablets are available for next day delivery.


17.Is it safe to buy Trimethoprim tablets online? 

Yes, as long as you are buying from a website that is a legally operating and regulated pharmacy it is perfectly safe to buy Trimethoprim online. The Independent Pharmacy is an NHS Online Pharmacy based in Bristol and has all the necessary regulation to be able to safely provide convenient access to genuine prescription treatments through our Online Pharmacy & Online Doctor. Our online prescribers always review your consultations thoroughly to ensure that your treatment is as safe and effective as possible.


18.How do I buy Trimethoprim online? 

It simple! Just select 'Start Consultation' above, you will need to fill in a simple health questionnaire so our GPs & Pharmacists can ensure it is safe for us to supply your Trimethoprim to you. It all takes around 3 minutes and your treatment can be delivered to your door.


19.What are the advantages of buying Trimethoprim online?

There are many advantages to buying Trimethoprim capsules online, some include:

It's quick & easy- there is no need to spend time at the doctor or pharmacy.

Fast delivery- We offer same day dispatch before 4pm and fast delivery to your address of choice with Royal Mail.

Great prices- we are able to offer very competitive prices and we guarantee to beat any other Online Doctor service.

Tons of information - we provide all the information you could need on Trimethoprim and other cystitis treatments, in easy to digest formats, at a time to suit you.


20.Will it stop my pill from working?

Trimethoprim will not stop your contraceptive pill (combined or progesterone only) from working. Only 2 antibiotics called rifamapacin and rifabutin affect the contraceptive pill from working.


21.What happens if it doesn’t work?

Trimethoprim is effective in 90% of cases and you should start to see a reduction in symptoms within 24 hours. If the symptoms have not reduced or got any better with 48 hours then you would need to see a doctor face to face.


They would take a urine sample and send it off for analysis, (it usually takes 2 days for the results to come back). They would then prescribe a specific antibiotic to your infection depending on the results.

Whilst you are waiting for the results the Doctor may prescribe another antibiotic like ciprofloxacin, norfloxacin, ofloxacin, co-amoxiclav or nitrofurantoin.


22.Can you take painkillers whilst being treated with trimethoprim?

You can take trimethoprim safely with any over the counter painkillers like aspirin, ibuprofen or paracetamol.


23.Can you treat cystitis in men online?

Cystitis is the inflammation of the urinary tract including the bladder. The bacteria move slowly up the urethra and multiply and this causes the burning, urgency and other cystitis symptoms.

The urethra is the tube that links the bladder to the outside world.

This tube is a lot longer in men than it is in women and makes it unlikely for men to suffer from cystitis. Therefore if you are a man suffering from cystitis symptoms you need to see a Doctor for a check up as the infection can be more serious. The doctor will need to rule out enlarged or infected prostate possibility of a blockage or tumours. This applies not only to trimethoprim but also to over the counter medicines as well.


24.Can I have a course of antibiotics as a back up?

Some women are prone to recurrent urinary tract infections and after visiting their Doctor they know the symptoms. Under these circumstances it is acceptable to have a small course of trimethoprim at hand so you can treat an infection quickly.


25.Will Trimethoprim give you thrush?

All antibiotics including trimethoprim reduce the bacteria in the body. After a course of antibiotics the bacteria in the vagina can be greatly reduced and this can cause the naturally occurring fungus to overgrow leading to thrush symptoms. Treatment is simple and varies from a capsule you swallow to a short course of creams or pessaries you apply. The full range can be seen here.


26.Does cranberry juice help treat cystitis?

It is thought that cranberry juice, extract or containing products stop the bacteris binding to the wall of the bladder. The jury is still oput on this even though there are some studies to show it is effective. Please rmemeber it doesn’t treat the sympotms or cure cystits.

The Independent Pharmacy is an online pharmacy and online doctor service is owned and operated by ABSM Healthcare Ltd (Company Reg. 08515600) and Red Label Medical Ltd (Company Reg. 08676338). All information that appears on this website is intended for information purposes only and should be used to supplement, not replace, your relationship with your local healthcare professionals. You should consult your doctor if you think you may have a health problem or before you start taking a new medicine. Please ensure you always read the information leaflets supplied with any medicinal products.For more information see our policies and terms and conditions at the bottom of every page. © 2014 ABSM Healthcare Ltd. All rights reserved.
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