Nytol Tablets (Original & One-A-Night)

221 reviews
In stock
  • Fast, discreet delivery

    Delivered in secure, plain packaging with tracked delivery from just £2.99

  • 100% UK-based pharmacy

    Our team of doctors and pharmacists, and our support staff, are all UK-based.

  • Free advice and support

    Have a question? Clinical support is always free; Monday - Friday, 9am - 5pm.

  • We're rated 4.9 out of 5
    Based on over 30,000 reviews collected on Google and Reviews.io.

Buy Nytol Online

from £5.59

Find yourself tossing and turning at night? Is falling asleep proving difficult, or do you wake up throughout the evening and struggle to drift off to sleep again? Both Nytol One-A-Night and Nytol Original sleeping aid tablets contain the active ingredient Diphenhydramine, a drowsy antihistamine which aids in the relief of temporary sleeplessness.

Taken 20 minutes before bed, Nytol sleeping aid tablets can help you to fall asleep more quickly, and improve the depth and quality of your sleep, too.

Treatment information
We stock 3 other treatments for Insomnia

Visit our Insomnia page for treatments, advice and FAQs.

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We’re a Fully Regulated Online Pharmacy

As a UK-based pharmacy, we follow the same strict regulatory standards as any physical pharmacy. Our expert clinical team and services are overseen by multiple regulatory bodies to ensure your care is always safe, secure and confidential.

Run by experienced healthcare professionals

We think accessing healthcare should be easy. Whether we’re fulfilling NHS prescriptions or helping people find the right treatments, we aim to offer our customers dependable, economical and convenient access to medicines with a personal and discreet service.

  • 12 qualified pharmacists
  • 60 years combined experience
  • 4.7 miltreatments delivered
  • 5 milregistered users
Meet The Team

Ordering as easy as 1, 2, 3

  1. 1. Find the ideal treatment

    We can provide over 1325 leading medicines to treat over 93 conditions.

  2. 2. Get a free consultation

    Our qualified healthcare professionals will assess your condition and needs.

  3. 3. Enjoy speedy delivery

    And when the time comes to re-order, it'll only take a couple of clicks.

MB ChB DRCOG MRCGP Dip.orth.med
GMC 3058367

Dr Donald Grant is The Independent Pharmacy's original online prescriber and is now our Clinical Advisor, using his wealth of experience to advise on clinical polices and prescribing guidelines. With over 30 years of experience, he is dedicated to enhancing the accessibility of online healthcare, ensuring that clinicians continuously pass on their knowledge to provide better care to patients. Dr Donald Grant has worked with pharmacists at The Independent Pharmacy since its inception. 

MPharm
GPhC 2079324

Scott is a co-founder and GPhC-registered pharmacist at The Independent Pharmacy. With 14 years of experience, Scott leads our digital strategy and is dedicated to ensuring online healthcare adheres to the highest safety standards. His areas of expertise include understanding digital healthcare delivery in the UK, particularly the regulatory frameworks, and how technology can be used to increase access to healthcare while reducing risk. Scott believes care should be individualised to meet the needs of the patient. He is also highly experienced in the digitalisation and automation of pharmacy dispensing and fulfilment.

Published 19 February 2020
Updated 21 November 2025
Reviewed 10 October 2024
Next review 10 October 2026