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Treclin Gel for Acne
What is Treclin gel?
Treclin gel is a topical acne treatment that is normally used to treat moderate levels of acne. It is a prescription only medicine that must be prescribed by a doctor or other healthcare professional. It can be bought online using The Independent Pharmacy after simply completing our quick, online consultation. Treclin gel is manufactured by Meda Pharmaceuticals and marketed by Mylan. It comes in 30g tubes and is a translucent yellow gel.
How does Treclin gel treat acne?
Treclin contains two active ingredients;
- Clindamycin - an antibiotic that helps to kill acne-causing bacteria that live on the skin.
- Tretinoin - reduces the ability of skin cells to stick together which helps to shed dead skin cells instead of them blocking follicles.
These two actions combine to help treat acne symptoms such as blackheads, whiteheads, pustules, papules and redness. The combination of the two active ingredients are more effective when combined than if used separately.
How quickly will Treclin treat acne?
Like most topical acne treatments, Treclin gel normally takes a few weeks of continued use to build up an effect. It is normally best to use the gel for a period of 10-12 weeks and it is important that you do not stop using Treclin as soon as your acne gets better.
You can read more about Treclin results here.
Non-prescription alternatives to Treclin acne gel include benzoyl peroxide gel, such as Acnecide. Benzoyl peroxide is an effective acne treatment that is available over the counter in most pharmacies. It helps to kill the bacteria that cause acne, however, it is not an antibiotic. Treclin gel should not be used in combination with benzoyl peroxide or any other treatment containing antibiotics.
Prescription alternatives to Treclin gel include:
- Topical antibiotics: Dalacin-T, Zineryt
- Retinoids: Differin
- Combinations: Duac gel, Epiduo
- Antibacterial: Skinoren
- Treclin gel Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.5371.pdf
Treclin gel should only be used on the skin. When applying Treclin gel, avoid getting it into the eyes, eyelids, lips, and nostrils.
Treclin should not be used in patients who:
- have a history of hypersensitivity to clindamycin and/or tretinoin or any of the excipients or lincomycin
- have regional enteritis, ulcerative colitis, or a history of any antibiotic-associated colitis
- have a personal or familial history of skin cancer
- have a history of acute eczemas, rosacea and perioral dermatitis
- have pustular and deep cystic nodular acne varieties (acne conglobata and acne fulminans)
Special warnings and precautions for use:
- Treclin is not for oral, ophthalmic, intranasal or intravaginal use
- Treclin is not recommended in treatment of mild acne vulgaris
- Treclin should not be used during pregnancy, especially during the first trimester and women not using contraception
- Contact with the mouth, eyes and mucous membranes and injured skin should be avoided
- In the event of accidental contact with the eyes, bathe with large amounts of water.
Antibiotic-associated colitis has been reported with the use of some other topical clindamycin products. This is unlikely to occur with Treclin as plasma levels have been determined and the percutaneous absorption of clindamycin is clinically negligible.
If you notice prolonged diarrhea or suffer from abdominal cramps, treatment with Treclin should be discontinued immediately as the symptoms may indicate antibiotic-associated colitis.
If severe irritation occurs you should discontinue temporarily or reduce the frequency of application.
Treclin should not be applied at the same time as other topical treatments, including cosmetics, as there is a chance of possible incompatibility.
Particular caution should be exercised in using keratolytic agents such as sulfur, salicylic acid, benzoyl peroxide or resorcinol and chemical abrasives.
Do not use any cleansers or scrubbing solutions with a strong drying effect. You should also avoid abrasive soaps, cosmetics, and spices or lime should be used with caution.
Photosensitivity may occur during treatment with Treclin Gel and exposure to sunlight should be limited as much as possible and appropriate sunscreen should be worn.
Avoid using sun-lamps or sunbeds throughout treatment as this product should not be used on sunburnt skin.
Long-term use of clindamycin may cause resistance and overgrowth of non-susceptible dermal bacteria or fungi, although this is rare.
Cross-resistance may occur with other antibiotics such as lincomycin or erythromycin.
Do not use if you are allergic to any of the ingredients listed in the 'Ingredients' section.
Tretinoin causes enhanced permeability for other topically applied medicinal agents.
Treclin in pregnancy, breastfeeding and fertility
Treclin should be given to women of childbearing potential only if effective contraception is used during treatment and for 4 weeks after stopping treatment.
There is not a substantial amount of data regarding the use of Treclin in pregnant women.
A limited number of pregnancies exposed in the first trimester to clindamycin indicate no adverse effects of clindamycin on pregnancy or on the health of the fetus/new-born child.
Clindamycin has been shown to not be teratogenic in reproduction studies in rats and mice when applied via subcutaneous and oral methods.
Treclin should not be used during pregnancy, especially during the first trimester, and in women who may become pregnant.
There is not adequate data on the effects of tretinoin and clindamycin and the secretion of breast milk following the use of Treclin. It is advised that Treclin is not be used by women who are breastfeeding.
Reproduction studies in rats and mice, using subcutaneous and oral doses of clindamycin, revealed no evidence of impaired fertility.
Orally administered tretinoin severely affects fertility. Available data regarding fertility after topical administration in humans are limited.
How to apply Treclin
Apply Treclin gel once daily at bedtime. Wash the entire face with mild soap and warm water. Pat dry using a towel. Use a pea-sized amount onto one fingertip, dot onto each area of the face: the chin, cheeks, nose, and forehead, then gently rub the gel over the entire face.
Do not use Treclin for more than 3 months without careful evaluation or consulting with a doctor. Any improvements may not be observed for up to several weeks after beginning treatment.
If you miss a dose of Treclin, just wait for the next dose at the usual time. Never double dose to make up for a forgotten dose.
Does Treclin go out of date?
The shelf life of Treclin is stated on the outer box and refers to the last day of that month. After you first open the tube, Treclin expires within three months.
Treclin gel ingredients
Each gram of Treclin gel contains:
- 10 mg (1%) clindamycin (as clindamycin phosphate)
- 25 mg (0.025%) tretinoin
- purified water
- methyl parahydroxybenzoate (E218)
- propyl parahydroxybenzoate (E216)
- polysorbate 80
- disodium edetate
- citric acid, anhydrous
- butylhydroxytoluene (E321)
Treclin side effects
Side effects may occur on areas of skin on which Treclin gel has been applied. If they cause too much of a problem, used Treclin less frequently or stop for a few days until the irritation goes away.
Side effects are most common during the first couple of weeks of using Treclin and are most likely to include dry skin, irritated skin (including stinging or burning) and peeling skin. These side effects tend to subside after a couple of weeks.
These minor side effects can include:
- slight stinging or skin pain
- skin irritation or tenderness
- skin burning sensation
- dry skin
Rare side effects (1 in 10,000 people):
- Eye irritation
- Herpes simplex
- Macular rash
- Skin bleeding
- Skin burning sensation
- Skin depigmentation
- Application site erosion or discolouration
Uncommon side effects (1 in 10,000 to 1 in 1,000 people):
- Dry skin
- Photosensitivity reaction
- Exfoliative rash
- Skin exfoliation
Ensure you read the Patient Information Leaflet thoroughly before starting Treclin gel.
Treclin Gel reviews
Treclin Gel FAQs
Before applying any topical treatment, always wash your hands and remove any makeup.
Gently wash the area with warm water and a mild soap, drying softly afterward.
Spread a thin layer of the gel onto the affected skin with your fingertips and gently smooth it in.
Apply to the entire area in which acne is present, not just each individual spot.
Always wash your hands after applying Treclin.
When using Treclin daily, it normally takes 4 - 12 weeks to see a substantial improvement in your acne. It is important to use the gel daily and to continue using Treclin when you start to see an improvement for the best effects.
If you experience side effects such as redness or irritation in the area of application, you should stop using Treclin gel until the symptoms resolve. When you restart the treatment, you should use it every other day for a week to ease yourself back into the treatment.
Treclin gel is a prescription acne treatment that cannot be bought over the counter from a local pharmacy. It needs to be prescribed by your GP or can be purchased from a registered online pharmacy, such as The Independent Pharmacy.
Treclin gel should not be used by women who are pregnant or are trying to become pregnant as it may harm your unborn baby. Women of child-bearing age you should use contraception while using this medicine and for one month after discontinuation of treatment.
Treclin gel contains the active ingredient, tretinoin. Tretinoin can make your skin more sensitive to light, leading to sunburn. It is recommended that you use sunscreen with at least SPF 30 if you will be exposed to strong sunlight to protect your skin. If you do experience sunburn whilst using the treatment, you should stop using Treclin until this has fully healed.
You should not use sunbeds or other UV lights whilst using Treclin.
We do not recommended patients to use other acne treatments at the same time as Treclin gel. Treclin is a combination treatment that has two active ingredients that work in different ways to cure acne. There are no other acne treatments that would enhance the effects of Treclin if used at the same time and combining it with other treatments will lead to an increased likeliness of side effects such as dry skin, irritation, redness, or burning.