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Ibuprofen 400mg Tablets

*The brand supplied may vary. Please contact us if you require a specific brand.

Ibuprofen 400mg Tablets (84 tablets )

Order before 3pm for delivery from Wed. 20 Jan and Thu. 21 Jan.

Description for Ibuprofen 400mg Tablets

Ibuprofen Tablets 400mg are orally taken pills to provide pain relief from typical discomforts such as headaches including migraines, rheumatic and muscular pain, dental pain, period pain, backache, neuralgia, as well as the symptoms and feverishness of the common cold and flu.

Product Information

  • Age: 12 years +

    Maximum per order: 2

  • Pregnancy: Not suitable

    Breastfeeding: Suitable

Ibuprofen Tablets 400 mg provide relief of mild to moderate pain from headaches (including migraines), rheumatic and muscular pain, sprains and strains, dental pain, menstrual pain, backache, neuralgia, as well as fever and symptoms of the common cold and flu.
Ibuprofen 400mg Tablets are nonsteroidal, anti-inflammatory drugs (an NSAID), which reduce inflammation and pain. Ibuprofen is a pain killer, a temperature reducer, and an anti-inflammatory.
Ibuprofen is sold under many different brand names. It is also commonly combined with decongestants in cold and flu remedies. Ibuprofen is also used in gels, sprays and mousses for topical application to reduce muscle aches and pains.
Ibuprofen alters the body’s response to pain, swelling and fever. It blocks the action of cyclooxygenase, a substance in the body involved in the production of various chemicals, including those produced in response to injury or disease and which cause pain, swelling and inflammation. 

To summarise, ibuprofen reduces the swelling and inflammation caused by the body’s immune system and is an effective painkiller. Popular brands that use ibuprofen include Nurofen and Cuprofen.
Prolonged and frequent use of ibuprofen might affect fertility in women although this usually reverses once treatment with ibuprofen has been stopped. 
Ibuprofen taken at the recommended dose does not effect a person’s ability to drive or operate heavy machinery. However, some patients may find that they feel dizzy after taking ibuprofen. If this occurs, you should not drive. Ibuprofen does not interact with alcohol, however heavy drinkers should avoid taking ibuprofen. Ibuprofen should be taken with or after food to reduce stomach irritation.
Other medications may also affect or be affected by ibuprofen. Always seek the advice of your doctor or pharmacist before you use ibuprofen tablets with other medications.
Ibuprofen tablets can be taken with food and drink.

Pregnancy, breast-feeding 
If you are pregnant or think you may be pregnant, breastfeeding, or are planning to have a baby, consult your doctor or pharmacist before taking ibuprofen.
Pregnant women should not use ibuprofen tablets during the last trimester of the pregnancy. For women who are planning a pregnancy or are pregnant, ibuprofen tablets should be avoided.
Treatment at any time during pregnancy should take place only under a doctor’s supervision. 
Ibuprofen tablets pass into breast milk and are therefore not recommended during breastfeeding.

Ibuprofen tablets may affect fertility and their use is not recommended while attempting to conceive or during investigation of infertility.
Driving and using machines

Ibuprofen tablets may cause impaired reactions in some people. Side effects such as dizziness, drowsiness, fatigue and visual disturbances are possible after taking NSAIDs. Patients who are affected should not drive or operate machinery.
You alone are responsible for deciding if you are condition to drive a motor vehicle or perform other tasks that demand increased concentration. Descriptions of ibuprofen’s effects can be found in other sections. Read all the information in this leaflet for guidance.
Contact your doctor, nurse or pharmacist if you have any questions about ibuprofen.
Ibuprofen tablets contain lactose monohydrate
Therefore, if you have an intolerance to some sugars, contact your doctor before taking this product.
Take these tablets with or after food or with a glass of milk to reduce the chance of stomach-related side effects.

Non-Prescription Alternatives for the treatment of Pain are;

  • Ibuprofen
  • Paracetamol
  • Aspirin
  • Topical Treatments (Ibuprofen gel)
  • Rest the area

If your pain does not ease or becomes severe, contact your GP or Pharmacist for further advice.

*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

Swallow ibuprofen tablets whole with plenty of liquid, with or after food. Wait at least 4-6 hours between doses. Do not take more than three tablets in one day.

Common side effects, may affect up to 1 in 10 people:

  • headache, lightheadedness
  • gastrointestinal problems such as diarrhoea, vomiting, nausea, abdominal pain, indigestion, flatulence, black stools, constipation,bleeding in stomach and intestine, vomiting blood
  • rash
  • fatigue


If you are concerned about these effects, or if the product affects you in a different way, stop using it and talk to your doctor or pharmacist.


Active ingredients:

Each film-coated tablet contains 400 mg ibuprofen

Inactive ingredients:

Lactose monohydrate, , croscarmellose sodium, microcrystalline cellulose, maize starch, magnesium stearate, colloidal anhydrous silica, hypromellose, triacetin, erythrosine aluminum lake (E127), titanium dioxide (E171).

Read the following warnings carefully to ensure you are selecting an appropriate product.

When used at high doses, anti-inflammatory/pain-killing medications like ibuprofen have been associated with an increased risk of heart attack or stroke. Do not take more than the recommended dose or exceed the suggested duration of treatment.

See your doctor or pharmacist before taking Ibuprofen tablets if you:

  • have heart failure, angina, or if you have had a heart attack, bypass surgery, peripheral artery disease or any kind of stroke.
  • have diabetes, blood pressure, high cholesterol, are a smoker, or have a family history of heart disease or stroke.
  • Try to take the lowest possible dose for the shortest amount of time to reduce the risk of side effects. Higher than recommended doses can entail risks and combining NSAID products should be avoided.
  • People who have or have had the following illnesses or symptoms should consult a doctor before taking ibuprofen tablets: systemic lupus impaired kidney or liver function, erythematosus, mild to moderate heart failure, inflammatory bowel diseases, asthma, previous stomach ulcer or other increased tendency to bleed.
  • This product belongs to a group of medicines (NSAIDs) which may impair the fertility in women. This effect is reversible upon stopping the drug.
  • Patients who have stomach prblems in the past, including the elderly patients, should contact a doctor if they notice abdominal symptoms.
  • Rare but serious skin reactions have been reported when using an NSAID. Patients seem to be at highest risk early in their therapy. Stop taking ibuprofen tablets and contact a doctor if you develop a rash or mucous membrane lesions.
  • Patients with Systemic Lupus Erythematosus and mixed connective tissue disorders may have an increased risk of aseptic meningitis.
  • Stop taking ibuprofen tablets and contact a doctor immediately if you develop any of the following symptoms:
  • swelling of the face, throat or tongue
  • swallowing difficulties
  • hives and difficulties breathing
  • Medications like ibuprofen tablets may entail an increased risk of heart attack or stroke.

This risk is more likely in the cases of high doses and long-term treatment. Do not exceed the recommended dose or treatment time.

  • Consult a doctor or pharmacist about using ibuprofen if you have heart problems, have had a stroke or if you think that you are at risk of developing these conditions.
  • If you are planning a pregnancy, consult your doctor before taking ibuprofen tablets.
  • Avoid use of this drug during varicella.
  • Rare but serious skin reactions have been reported when using a NSAID. These include a rash.The rashes may include blisters on the skin, especially on the legs, arms, hands and feet. It can also affect the face and lips.

The reaction can worsen if the blisters grow and parts of the skin slough off. There could also be severe infection with destruction of skin, subcutaneous tissue and muscle.

  • Ibuprofen tablets may cause white blood cells to reduce and your resistance to infection may decrease as a result. If you experience symptoms of and infection (a fever, sore throat, urinary problems or a sore pharynx/mouth) you should see your doctor immediately. Your blood will need to be tested for possible reduction of white blood cells. Inform your doctor about the medication you take.
  • You have intolerance to some sugars.

Children and adolescents

Children and adolescents risk renal impairment if they are dehydrated.

Other medicines and ibuprofen tablets:

Do not use other pain-relieving medications at the same time unless advised by a doctor.

Tell your doctor or pharmacist if you take, have taken or might take any other medications, including over-the-counter and prescription medications.

Ibuprofen tablets may affect or be affected by the following:

  • methotrexate, tacrolimus ciclosporin, pemetrexed (for tumours and immune system disorders)
  • lithium (for manic depressive illness)
  • digoxin (for irregular heart beat)
  • acetylsalicylic acid (for pain)
  • anti-coagulants (i.e. to thin blood/prevent clotting e.g. aspirin/acetylsalicylic acid, warfarin, ticlopidine, dicumarol),
  • SSRIs (for depression)
  • ACE-inhibitors such as captopril, beta-blockers such as atenolol medicines, angiotensin-II receptor antagonists such as losartan (for high blood pressure)
  • corticosteroids (for inflammation)
  • voriconazole or fluconazole (for fungal infections)
  • sulphonylureas (for diabetes mellitus)
  • zidovudine, ritonavir (for HIV treatment)
  • quinolones such as ciprofloxacin (antibiotics)
  • aminoglycosides (a type of antibiotic)
  • mifepristone
  • probenecid
  • any other medications that include ibuprofen
  • any other anti-inflammatory pain killer, including acetylsalicylic acid
  • cholestyramine (to lower cholesterol)
  • Gingko biloba herbal medicine


Side effects

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2 - 3 day delivery - £2.95
  • Express Tracked Delivery - 1 - 2 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail & DPD orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email, in your online account and from any notifications from your courier.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail


  • Fully tracked delivery
  • SMS & email notifications
  • Four-hour delivery window
  • Change delivery date directly with Royal Mail
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local Post Office or Royal Mail Customer Service Point.

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.




  • Fully tracked delivery
  • SMS & email notifications
  • One-hour delivery window
  • Change delivery date directly with DPD
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local collection point.

DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Pain?

Visit our advice area or contact our support team

Ibuprofen 400mg Tablets Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Frequently Asked Questions

  • What is ibuprofen used for?

    Ibuprofen relives mild to moderate pain such as headache, dental pain, menstrual pains, backache, muscular aches and pains, rheumatic pain and neuralgia. Ibuprofen reduces fevers symptoms of cold and flu, and inflammation. 

  • Can I take ibuprofen if I am pregnant or breastfeeding?

    Check with your GP as he/she may recommend its use during pregnancy to treat inflammation and to reduce a fever. However, ibuprofen should NOT be taken after 30 weeks of pregnancy. Overall, no significant evidence has suggested that taking ibuprofen during pregnancy is harmful. 

    During breastfeeding, doctors recommend paracetamol for pain relief. However, if a breast feeder takes Ibuprofen, only a small amount of the medication will enter into the milk.

  • Will taking ibuprofen interfere with other medications?

    Ibuprofen may effect prescribed and over-the counter medications. Contact your GP or read the enclosed instructions prior to use. Some common medications that ibuprofen may interfere with include: antihypertensives • anti-inflammatories • digoxin • lithium • tacrolimus • SSRI antidepressants • warfarin • aspirin 

Authored By:

A photo of  Andy Boysan

Andy Boysan


Published on: 29-05-2019

Last modified on: 29-05-2019

Andy is a co-founder, the superintendent pharmacist and director at The Independent Pharmacy.

Reviewed By:

A photo of  Chris Newbury

Chris Newbury

BPharm IP

Reviewed on: 29-05-2019

Next review date: 29-05-2021

Chris is a vastly experienced clinical pharmacist and has been registered as an Independent Prescriber since 2014.

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