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Rozex 0.75% Gel

Rozex 0.75% Gel (40g)

Order before 3pm for delivery from Sat. 07 Aug.

Rozex (metronidazole) rosaceca treatment

Rozex is an effective rosacea treatment based on the powerful antibiotic metronidazole. Rozex 0.75% gel works fast to kill the bacteria that cause rosacea. It works the same as Rozex cream as they have the same quantities of the active ingredient (metronidazole). It’s so easy to use; just apply it twice daily and it can clear up your skin condition in a matter of months.

To buy Rozex, you’ll need an online prescription from one of our medical professionals. Click ‘start consultation’ above to get started with a free consultation today and they’ll see if Rozex is right for you. If it is, you can buy it directly from The Independent Pharmacy at a competitive price. Order today and receive same day dispatch (before 4pm) to any UK address.

Read Rozex gel reviews from our patients who have used this treatment.

Rozex - Important Information

  • Age: 18 Years +

    Maximum per order: 4

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

What’s in Rozex 0.75% Gel?

Rozex 0.75% Gel contains the active ingredient of metronidazole in a strength of 0.75%, and is mainly used to treat the condition of rosacea. Because of its potency, it is classified as a prescription-only-medicine, and every 40g tube of gel comes with a comprehensive Patient Information Leaflet. Be sure to speak to a doctor or pharmacist before and during your Rozex treatment.


Rosacea relief through Rozex Gel: clear up skin irritation

Rozex Gel contains works quickly to treat rosacea, a chronic condition caused by inflammation. Rosacea usually occurs on the cheeks, nose, forehead, chin and eyelids. It can result in acne-like outbreaks or increased redness in these areas of the face. When you apply Rozex Gel or cream, it treats the skin infections that cause or worsen skin irritation, bringing down the inflammation and redness.

Once you start using Rozex, it will usually take two to three months for the skin to become clear from spots. Even if you’re not yet seeing results after a while, it is recommended that you finish the prescribed treatment. Rozex Gel treatment doesn’t usually go longer than four months (your doctor will inform you if there’s good reason to use it for longer than that). Read our full guide on how long Rozex takes to work for a better understanding of what to expect.


Metronidazole — a powerful antibiotic

Rozex works because of metronidazole, its active ingredient. Metronidazole belongs to a group of medicines called nitroimidazole antibiotics. It is used to treat infections caused by bacteria and other microorganisms called protozoa. It eliminates them by damaging their DNA, leaving them unable to multiply.


Managing rosacea without medicine

You cannot buy Rozex cream over the counter but there are some non-prescription alternatives that can help with the treatment of your rosacea, such as:

  • Consistently protecting your skin from the sun
  • Avoiding scrubbing or irritating your face
  • Using only unperfumed moisturisers on your sensitive dry skin
  • Avoiding using perfumed soap on your face
  • Tracking the lifestyle factors that trigger your rosacea flare ups (keep a diary)

If you try all of these options but your rosacea is still a huge problem, Rozex 0.75% Gel might be just what you need. Consult our Online Doctor to confirm whether it’s the best choice for you.


Alternative treatments for rosacea

Rozex Gel is a great choice for treating mild to moderate skin eruptions and inflammation in rosacea sufferers. It is used twice a day and needs to be used continuously for several weeks for an improvement to be seen. Side effects are moderate as it is applied locally and little is absorbed into the bloodstream. Metrogel is an alternative to Rozex gel that also contains metronidazole.

Mirvaso Gel is specifically used to reduce the skin redness that occurs in rosacea. You can apply it once per day, and it will work to reduce redness for as long as you need it. The main side effect of Mirvaso Gel is worsened redness at the start of treatment.

For more serious flare-ups, Finacea gel can be used — with anti-inflammatory and antibacterial properties, it treats rosacea very effectively (and it contains azelaic acid, which is believed to also be good for the skin in other ways).

A relatively new rosacea application that many people are finding success with is Soolantra, which contains the active ingredient of ivermectin. Both anti-inflammatory and anti-parasitic, it attacks the human skin parasites commonly linked with rosacea — as such, it may prove effective in cases where Rozex has no success.

Erythromycin is an oral antibiotic used to treat the same symptoms as Finacea and Rozex, but it is only considered when rosacea is very severe or unresponsive to the creams and gels. It takes 4 to 6 weeks of treatment for Erythromycin to show results, and it cannot be taken with any foods or medicines that contain metal ions (anything containing calcium or large quantities of iron or calcium will combine with the Erythromycin and prevent it from being absorbed). Erythromycin should be taken in courses of 6 -12 weeks.


Applying Rozex Gel when pregnant or breastfeeding

Metronidazole, the active ingredient in Rozex, enters the bloodstream in low amounts after being applied, and it’s unknown how that might affect a pregnancy or a breastfed baby. Unless your GP says Rozex is required in your case, do not use it while pregnant or breastfeeding.

Rozex 0.75% Gel Patient Information Letter: https://www.medicines.org.uk/emc/files/pil.924.pdf

*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

How to apply Rozex Gel

  • First, wash and dry the affected areas of your skin.
  • Apply a thin layer of the gel to all the affected areas. Rub the gel in well.
  • Always replace the cap and wash your hands after use.
  • Rozex gel should be used in this way twice a day, morning and evening.

Rozex gel should be used in this way twice each day, once in the morning and again in the evening. If used for three to four months, it should help clear up your rosacea (Rozex Gel should be used for a minimum of three months to see the full effect).

If your rosacea has not fully cleared up over three or four months, you might want to undergo another three-to-four-month course of treatment. See what your doctor recommends.

Rozex side effects

Like all medicines, Rozex can cause side effects which are most likely to occur at the start of treatment. Most side effects last for less than a week and are mild.

Common side effects of Rozex Gel can include:

  • Dry skin
  • Redness of the skin (erythema)
  • Itching of the skin (pruritus)
  • Skin discomfort (burning, pain, stinging)
  • Skin irritation
  • Worsening of rosacea

If you experience side effects when using Rozex Gel, you try decreasing the frequency of application to once daily for a week or so, then build back up to twice daily if the side effects have abated. For further information on Rozex gel and its side effects, see the Patient Information Leaflet contained within your medicine, or consult our medical team.

Rozex ingredients

Rozex contains 0.75% w/w of the active substance Metronidazole.

The other ingredients are as follows:

  • Carbomer 940
  • Disodium Edetate
  • Methyl Parahydroxybenzoate
  • Propyl Parahydroxybenzoate
  • Propylene Glycol
  • Sodium Hydroxide
  • Purified Water

Rozex gel warnings

Do not use Rozex if you are allergic to metronidazole or any of the other listed ingredients. An allergic reaction to Rozex may produce a rash or itching. Do not use Rozex while pregnant or breastfeeding unless a doctor says it’s essential.

Before using Rozex, talk to a doctor or pharmacist, and take the following precautions:

  • Never get the cream in your eyes. If you do, rinse thoroughly with large amounts of warm water or eye wash until it’s completely gone from the area.
  • If you suffer from any blood disorders, be sure to get confirmation from your doctor that Rozex is safe for you before you use it.
  • Do not use Rozex to treat children.
  • Avoid strong sunlight (including sun-bathing) and exposure to ultra-violet light (eg. solariums, sun-lamps) while you are using Rozex.
  • Once your rosacea has fully cleared up, stop your course of treatment.

If you are taking, have recently taken, or intend to take any other medicines in the near future, inform your doctor before using Rozex. It could interfere with certain other drugs used to reduce blood clotting (anticoagulants) such as warfarin and dicoumarin.

Because metronidazole can react with alcohol (and contains cetostearyl alcohol), it is advised that you avoid alcohol while using Rozex gel.

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2 - 3 day delivery - £2.95
  • Express Tracked Delivery - 1 - 2 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail & DPD orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email, in your online account and from any notifications from your courier.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail


  • Fully tracked delivery
  • SMS & email notifications
  • Four-hour delivery window
  • Change delivery date directly with Royal Mail
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local Post Office or Royal Mail Customer Service Point.

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.




  • Fully tracked delivery
  • SMS & email notifications
  • One-hour delivery window
  • Change delivery date directly with DPD
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local collection point.

DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Rosacea?

Visit our advice area or contact our support team

Rozex 0.75% Gel Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Frequently Asked Questions

  • What is Rozex?

    Rozex is a gel containing the antibiotic and antiprotozoal medicine, metronidazole. It is used to treat pustules and pimples (and the redness & inflammation associated with them) found on the face in mild to moderate rosacea. It is not related to penicillin and can be used with penicillin allergies.

    Read more about Rozex gel uses here.

  • How does Rozex work?

    Metronidazole, the active ingredient in Rozex gel, interferes with DNA inside bacterial and protozoan cells and prevents new DNA from being formed. This kills existing bacteria and stops bacteria from being formed. This helps to treat the infection and reduce rosacea symptoms.

  • How do I apply Rozex?

    1. Wash and dry your face first.
    2. Using a clean finger, apply a thin layer of Rozex gel evenly over the affected area twice daily.
    3. Avoid applying the gel to wet skin as it may run in to eyes or mouth.
    4. Rozex is not to be used anyone under the age of 18.
    5. Avoid getting gel in the eyes, mouth or nostrils and wash with plenty of water if this occurs.
    6. Rozex gel becomes ineffective when exposed to strong sunlight or sun lamps. Use a high factor sun cream when exposed to strong UV light to ensure Rozex remains effective.
    7. Apply any cosmetics or make up after the gel has been absorbed and dried.
  • What’s the difference between Rozex and other rosacea treatments?

    Rozex Gel is used to treat mild to moderate skin eruptions in rosacea and the inflammation that is associated with it. It is used twice a day and needs to be used continuously for several weeks for an improvement to be seen. Side effects are moderate as it is applied locally and little is absorbed into the bloodstream.

    Mirvaso Gel is used to reduce the redness on the face that occurs in rosacea. It is applied daily to the affected areas and continues to work for as long as it is used. The most common side effect of Mirvaso gel is worsening redness at the start of treatment.

    Skinoren Cream is also used for the same symptoms, applied twice a day and can take several weeks for the results to be seen. However the effects of Skinoren may be slightly better compared to Rozex, however it has a higher chance of side effects.

    Erythromycin is an oral antibiotic used to treat the same symptoms as Skinoren and Rozex. However it is used when the condition is severe or unresponsive to the creams and gels. The effect is usually seen after a 4 - 6 weeks if taken continuously. They cannot be taken at the same time as foods or medicines that contain metal ions. Calcium in milk and iron in indigestion remedies are good examples that combine with these antibiotics and make them inabsorbable.

  • Is it safe to use Rozex continuously?

    Rozex needs to be used continuously for a least a few weeks for the positive effects to be seen. If you miss an application, apply it when you can. If it’s time for the next treatment by the time you remember, don’t apply it twice. Forget about the missed treatment and resume your normal schedule. Do not apply Rozex more than twice a day, or use a double dose in any circumstances.

  • What are the side effects of Rozex?

    As Rozex is applied topically and only a small amount enters the circulation, side effects tend to be limited to where it is applied. Dryness, itching, a burning sensation and possibly worsening of rosacea symptoms are the most common side effects that affect up to 10% of patients.

    We are all different and how we react to medication varies form one person to another. Although the side effects of medication can be daunting, not everybody will suffer with them.

  • How long will it take for Rozex work?

    Depending on the case, it can take a few weeks of continuous use before the positive effects of Rozex become apparent.

    Read our ‘how long does Rozex cream take to work’ guide for more info.

  • Can I use Rozex and wear make up?

    Yes, you can. You just need to apply the Rozex first and allow it to absorb and dry before you apply make up and/or any other cosmetics.

  • Is there anyone who should not use Rozex gel?

    Although unlikely, patients who are on blood thinning medication should not use Rozex because of the small chance it may interfere with the blood clotting action of your medicaitom.

    Patients who suffer from other blood disorders are also advised not use Rozex.

  • Can I use Rozex with other medication?

    The chance of interaction of Rozex with other medicines is low because very little of it is absorbed in to the blood stream.

    Alcohol taken whilst being treated with metronidazole tablets can cause nausea and vomiting, however is unlikely with the topical gel. Even though the chances of this reaction happening with the gel are small, the manufacturer still advises that patients still avoid alcohol whilst using Rozex gel.

  • Is it safe to apply Rozex gel when pregnant or breastfeeding?

    The active ingredient from this topical treatment, Metronidazole, passes into the bloodstream in low amounts after application to the skin. However, its safety during pregnancy has not been established. Therefore, Rozex should not be used during pregnancy or while breastfeeding unless considered absolutely essential by a doctor.

  • Is Rozex an antibiotic?

    Rozex contains the active ingredient Metronidazole, which is an antibiotic.

  • Can Rozex irritate my skin?

    In rare cases, yes. If your skin becomes irritated when using this gel, try using it less frequently or have a break for a few days. Consult your doctor if it persists.

  • Is Rozex used to treat acne?

    No. While some cases of rosacea may manifest themselves in acne-like pimples, acne and rosacea are two different skin conditions and are treated in different ways.

  • Can I drink alcohol while using Rozex treatment?

    It is advisable that you avoid drinking alcohol when using Rozex. This is because Metronidazole is an antibiotic that can react with alcohol, causing side effects such as hot flushes and abdominal cramps.

  • Is Rozex a steroid?

    No, Rozex is not a steroid. It is recommended that you avoid using steroid treatments on Rosacea, as it may irritate your skin further.

  • What kind of moisturiser should I use when suffering with rosacea?

    It’s important to use a non-comedogenic moisturiser on dry areas of skin when suffering from rosacea. Any oil-based moisturiser may further irritate the skin by clogging pores.

  • Do I have rosacea or dermatitis seborreica?

    Seborrheic dermatitis is also an inflammatory skin disorder, and most commonly appears inside the ears, on the forehead, in the eyebrows, and around the nose. It’s characterised by scaly/greasy/yellow patches of skin and is often accompanied by dandruff – but no acne bumps or pustules, as with rosacea.

    If you’re uncertain what you’re suffering from, get a free online consultation and we’ll help to identify your condition. Often, people with rosacea also have seborrheic dermatitis, and these different conditions must be treated separately. If you’re only suffering from dermatitis, you will likely be prescribed a treatment like E45 Itch Relief Cream or Dermol Cream.

  • How long should you use Rozex for?

    You should use this gel for as long as your doctor recommends – this will usually be for 3-4 months, until your rosacea has cleared up. However, this may be extended depending on how your skin responds to treatment.

  • How should my Rozex be stored?

    You should store your Rozex Gel 0.75% at room temperature at or below 25°C, but do not keep in a fridge or freezer.

Authored By:

A photo of  Andy Boysan

Andy Boysan


Published on: 02-02-2017

Last modified on: 10-02-2020

Andy is a co-founder, the superintendent pharmacist and director at The Independent Pharmacy.

Reviewed By:

A photo of  Scott McDougall

Scott McDougall


Reviewed on: 10-02-2020

Next review date: 10-02-2022

Scott is one of the two founders of The Independent Pharmacy. He is a registered pharmacist and the registered manager of our service with the CQC.

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