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Tadalafil 20mg Tablets (Generic Cialis)

*The brand supplied may vary. Please contact us if you require a specific brand.

Tadalafil Tablets (10mg & 20mg)

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Order before 3pm for delivery from Tue. 22 Jun and Wed. 23 Jun.

Buy Tadalafil Tablets Online from a UK Pharmacy

You can buy Tadalafil online today from The Independent Pharmacy — the safe online pharmacy you can trust — and receive it the very next day in plain discreet packaging. 

Tadalafil is a generic version of the popular ED treatment Cialis and is prescription-only treatment in the UK. By filling in a short online consultation, our team of qualified healthcare professionals can ensure it will be safe and effective for you, before giving our in-house pharmacy a prescription to send your treatment directly to your door.

Tadalafil - Important Information

  • Age: 18 Years +

    Maximum per order: 12

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Meet generic Cialis

Tadalafil tablets are a cheaper generic form of the branded erectile dysfunction medicine Cialis. They are just as effective at treating erectile dysfunction (ED) and you can buy them online much more cheaply than the popular branded Cialis.

Tadalafil (Generic Cialis) is now available for sale in the UK as a cheaper form of ED medication because of the expiration of the Cialis patent.


How does Tadalafil work?

Tadalafil tablets tackle ED by increasing the flow of blood to your penis, helping you to both achieve, and maintain, a healthy erection (this is how most ED tablets work).

They begin to take effect after 30-60 minutes and once one tablet has been taken, it is then effective for up to 36 hours - much longer than the 4 - 6 hours normally associated with Sildenafil.

It's important to remember that Tadalafil tablets do not work without sexual stimulation — they will not produce an erection without you being sexually stimulated or ‘turned on’. This is because the drug Tadalafil enhances the chemical messages responsible for producing an erection; it does not, and cannot, fully replace or replicate these messages. Tadalafil does not give you a 36-hour erection - it simply allows you to achieve an erection with stimulation within this time period.

For more about how the drug works, visit our what is Tadalafil and how does it work page.


What causes ED?

There are many causes of ED and it affects men of all age and health levels. However, ED has been reported to be a symptom of early stage diabetes, high blood pressure, and poor circulation, while it is also more common in men who are smokers and/or overweight.

ED can also be caused by stress, smoking, alcohol and fat consumption, and cycling for over 3 hours a day.

Failing to treat ED can lead to stress, anxiety, depression, and difficulties in your close relationship(s).

You can find out more here on our: What causes ED? page.

What other ED treatments are there?

In addition to generic Cialis/Tadalafil tablets, there are a further ED seven medications that you can purchase online from The Independent Pharmacy. These are:

Tadalafil is very similar to sildenafil (Viagra) and other ED treatments in effectiveness, however, it lasts much longer, making it a better option for weekend use. No combination of Viagra/Sildenafil, Cialis, Levitra, Spedra or other ED treatment should be used at the same time – you should leave a break of up to 24 hours (36 hours for Cialis/generic Cialis Tadalafil).

There are also a series of non-prescription alternatives available for treating ED. These include:

  • Changes to your diet (such as reducing your alcohol and fat consumption)
  • Counselling
  • Lowering your stress levels
  • Stopping Smoking
  • Vacuum Devices (Penis Pumps).

Find more ED treatments here.



*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.


Take ONE Tadalafil tablet per day – no more than one. You should not repeat the dose, or take another ED treatment, within a 36-hour period.

Tadalafil tablets are designed on an ‘as required’ basis, which means that you should only take them when you believe that you require help in achieving and maintaining an erection.  

Tadalafil tablets can be taken either with or without food but should be taken orally, with water, and swallowed whole when you take them.  

Tadalafil tablets are available in 10mg & 20mg strength, for more information on which is right for you, read our Tadalafil dosage information page.

Side effects

Please be aware that medication affects people who are taking it in different ways – people who take Tadalafil tablets will not necessarily experience any of the known side effects listed below. 

Over many years, Cialis and Tadalafil have been used by millions of men and shown to be generally safe and effective for most men. Below are some of the known and associated side effects that you may experience when taking Tadalafil tablets:

  • Back pain
  • Flushing
  • Headache
  • Heartburn (reflux)
  • Indigestion (dyspepsia)
  • Nasal congestion
  • Pain in the muscles (myalgia)

Uncommon frequency: Affects between 1 and 10 people out of every 1000.

Click here for more information on Tadalafil side effects.


Tadalafil tablets contain 10mg or 20mg (depending on the strength) of Tadalafil as the active ingredient.

The inactive ingredients contained in Tadalafil tablets are:

  • Lactose Monohydrate
  • Croscarmellose Sodium
  • Hydroxypropylcellulose
  • Microcrystalline Cellulose
  • Sodium Lauryl Sulfate
  • Magnesium Stearate


You must take the following warnings into consideration when you are taking Tadalafil:

  • You should not take more than 1 Tadalafil tablet per day
  • Tadalafil tablets can cause dizziness, which could affect your ability to drive or operate machinery safely. You must not drive or operate machinery until you are aware of the effect the medication will have on you.
  • If taken in conjunction with alcohol, Tadalafil tablets could cause a drop in your blood pressure. Consuming alcohol while taking Tadalafil tablets may also impair your sexual performance.
  • If taken in conjunction with alcohol, Tadalafil tablets could increase the level of the medication within your bloodstream. This would in turn increase the risk of you experiencing the associated side effects,
  • If while taking Tadalafil tablets you have an erection which lasts for over 4 hours, then you must consult a doctor immediately. If you delay receiving treatment for a prolonged erection (priapism) for over six hours, this could cause damage to the erectile tissue in the penis and irreversible ED.
  • If when taking Tadalafil tablets you experience a partial decrease or loss of vision in one or both eyes, you must cease taking the medication and consult your doctor immediately.

You should take Tadalafil tablets with caution in the following cases:

  • If you have decreased kidney function
  • If you have decreased liver function
  • If you have a disease involving the heart and blood vessels (cardiovascular disease)
  • If you have a physical abnormality of the penis, such as severe curvature, scarring or Peyronie's disease
  • If you have a condition such as sickle cell disease, bone marrow cancer (multiple myeloma) or leukaemia, in which there is an increased risk of prolonged erections
  • If you are taking medicines for high blood pressure. These medications include:
    • Alpha-blockers
    • 5-alpha Reductase Inhibitors
    • Ketoconazole Tablets
    • Protease Inhibitors
    • Phenobarbital
    • Phenytoin
    • Carbamazepine
    • Rifampicin
    • Erythromycin
    • Clarithromycin
    • Itraconazole

Tadalafil tablets should NOT taken by the following persons, or if the below circumstances are true for you: 

  • Women
  • Children and adolescents under 18 years of age
  • Conditions where sexual activity is not advisable, for example severe heart disorders
  • You have an angina which is not well controlled by medical treatment (an unstable angina)
  • You have an angina that occurs during sex
  • You have had a heart attack in the last three months
  • You have had a stroke in the last six months
  • You have had mild to severe heart failure in the last six months
  • You have an abnormal heartbeat (arrhythmias) not controlled by treatment
  • You have uncontrolled high blood pressure (hypertension).
  • You have low blood pressure (hypotension)
  • You are taking any form of nitrate medications, e.g. glyceryl trinitrate (see end of fact sheet for more examples)
  • If you have ever experienced an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION). This condition causes a sudden, partial decrease or loss of vision in one or both eyes due to damage to the optic nerve. It can be temporary or permanent. Talk to your doctor if you have ever experienced this
  • You have hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption (Tadalafil tablets contain lactose)
  • You have severely decreased kidney function or kidney failure.

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2 - 3 day delivery - £2.95
  • Express Tracked Delivery - 1 - 2 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail & DPD orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email, in your online account and from any notifications from your courier.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail


  • Fully tracked delivery
  • SMS & email notifications
  • Four-hour delivery window
  • Change delivery date directly with Royal Mail
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local Post Office or Royal Mail Customer Service Point.

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.




  • Fully tracked delivery
  • SMS & email notifications
  • One-hour delivery window
  • Change delivery date directly with DPD
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local collection point.

DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Erectile Dysfunction (ED)?

Visit our advice area or contact our support team

Tadalafil Tablets (10mg & 20mg) Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Frequently Asked Questions

  • Do I need a prescription to buy Tadalafil?

    A GP needs to assess the suitability of this ED treatment before it can be prescribed for you.

    They will check your medical history and other medications that you’re on. Tadalafil is a widely prescribed treatment, but it can be unsuitable for some men. Your doctor will tell you more.

    If you buy Tadalafil online from The Independent Pharmacy, we take care of the prescription for you, our doctors will send it straight to our pharmacy to send out to you the same day.

  • What are the advantages of Tadalafil compared to other ED medications?

    Among the available ED medication, Tadalafil is known as ‘the weekend pill’. This is because once you have taken a dosage, the drug remains active for 36 hours.

    Most of the other major ED tablet medication on the market (such as Viagra) remain active for four to six hours. Topical agents and urethral suppositories begin working within minutes, but they remain effective for between one and two hours.

    Another advantage of Tadalafil is that it gives you the option to be spontaneous – Tadalafil takes 30-60 minutes to take effect once administered, and no prior dosage is required.

  • How long will an erection last on Tadalafil?

    Tadalafil will be effective for up to 36 hours. However, this doesn’t mean that you will have an erection for the duration of this time, as sexual stimulation is required in order for you to achieve an erection while taking Tadalafil.

  • How effective are Tadalafil 10 mg and 20mg tablets?

    Tadalafil has a similar rate of success to Sildenafil (this drug is sold under the brand name Viagra, among others, and is perhaps the most established drug on the market for ED).

  • Is Tadalafil better than Viagra?

    Both Tadalafil and Viagra are effective treatments for ED. However, as outlined above, the effects of Tadalafil last longer than Viagra.

  • What treatment strengths are available?

    There are two strengths of Tadalafil tablets available: 10mg and 20mg.

    We recommend that men trying Tadalafil tablets for the first time start with 10mg and can then move to the higher dose if necessary.

  • What strength do I start on?

    It is recommended that you begin by taking a lower strength tablet and build up as needed. 

    One type of tablet may work better than another and you should always consult your doctor before you begin your course of medication.

  • Can I take Tadalafil even if I don’t have ED?

    You should only take Tadalafil if you are experiencing ED and should not take it for the purpose of sexual enhancement.

  • Can I take Tadalafil alongside my other medications?

    You are able to, but this depends on the type of medications you are taking.

    Your doctor will review your medical history when prescribing Tadalafil, which will include any past or current medications you are using. 

    Your doctor will check for any interactions between Tadalafil and your medications and advise you accordingly on whether your past or current medication restricts you from taking Tadalafil.  

  • Can I drink grapefruit juice when taking Tadalafil?

    Grapefruit juice should be avoided if you are taking Tadalafil. 

    Grapefruit juice can affect how your system metabolises medicine, and this means that drinking it while taking Tadalafil may increase your sensitivity to side effects of taking the medication.

  • What should I do if my Tadalafil dosage does not work?

    If you do not see an improvement in your ability to achieve and maintain an erection while taking Tadalafil, then you should speak with your doctor. 

    Your doctor may then change the dosage of Tadalafil you are taking, or refer you to a different form of ED medication.

  • Can I buy Cialis/Tadalafil online?

    Yes, but you will have to undertake a short medical consultation with an online doctor first, as Tadalafil is only available on prescription in the UK. Always buy from a reputable, registered pharmacy.

  • Can I take two Cialis/Tadalafil tablets at once?

    20 mg is the maximum dosage of Tadalafil, and this should never be exceeded. Rather than taking two 10 mg tablets, it’s recommended that you switch over to higher dosage 20mg ones. Taking more Tadalafil will not help you get a better erection, but it could cause dangerous side effects.

  • How long does it take for Tadalafil to get out of my system?

    Tadalafil takes about thirty minutes to have an effect, and then it stays active in the body for up to 36 hours. Remember that Tadalafil only works to produce an erection when you are sufficiently sexually stimulated — it cannot produce an erection on its own.

  • Is Tadalafil safe?

    As with all prescription medications, it’s important that you check with the doctor before starting your course of treatment to ensure that it’s the right one for you. There are some people who should not take ED medication. Tadalafil is just as safe and effective as the branded Cialis, which is a hugely popular ED treatment.

  • Can I drink alcohol while taking Tadalafil?

    Yes, but it’s only safe in small quantities. Overdoing it with alcohol while on Tadalafil could lead to an increase in side effects and also makes ED worse.

Authored By:

A photo of  William Obeng

William Obeng

MPharm IP

Published on: 07-11-2017

Last modified on: 28-08-2019

Reviewed By:

A photo of Dr Donald Grant

Dr Donald Grant

MB ChB DRCOG MRCGP Dip.orth.med

Reviewed on: 28-08-2019

Next review date: 28-08-2021

Dr Don Grant is a GP with over 30 years experience and is the Clinical Advisor at The Independent Pharmacy

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