Vitaros cream is an easy-to-apply, fast-acting topical treatment for erectile dysfunction. It is a great option for treating ED where tablets such as Viagra or Cialis have not been effective or are not a desirable solution. Vitaros cream can produce a satisfactory erection in as little as five minutes and normally produces an effect for one to two hours.
Vitaros (alprostadil) is a prescription-only treatment for erectile dysfunction which was launched in the UK in June 2014. Vitaros is available as a cream in individual applicators - there are four applicators in a pack. Vitaros is an alternative treatment for men who have not achieved satisfactory results with tablet treatments (PDE5 inhibitors), or who cannot tolerate the side effects of these tablets.
The active ingredient in Vitaros Cceam is alprostadil, which treats ED in men. It should be applied before sex to achieve an erection in 5 - 30 minutes. Vitaros is easy to apply and may be more convenient than taking a tablet for some men. Because it acts locally, Vitaros cream’s effects normally only last for one to two hours, as opposed to the four to six hours of most tablet ED treatments. This may be ideal for men who only want a short period of action due to side effects or other reasons.
Vitaros cream should be kept in the fridge. It can remain outside of the fridge for up to 72 hours and still retain its effectiveness. Over 72 hours outside of the fridge, however, may make the product less effective and use is not recommended. When you receive Vitaros, you should immediately store it in the fridge to ensure the product remains viable. You can remove it from the fridge on the day of use to apply it at room temperature or to take with you if travelling.
The first time you use Vitaros, it may not be fully effective. Use it for at least four applications on separate occasions before switching treatments. Never apply more than one dose of Vitaros at a time, even if it is ineffective.
Vitaros cream is not a contraceptive and does not protect against sexually transmitted diseases; you should still wear a condom while using Vitaros.
Vitaros cream is generally well-tolerated with few side effects. Most side effects are local and last for one to two hours. For this reason, Vitaros could be a good alternative for men who cannot use ED tablets due to the side effects.
Please read the Patient Information Leaflet before you use Vitaros.
The active ingredient in Vitaros is alprostadil, a prostaglandin. Alprostadil is identical to prostaglandin E1, a chemical that occurs naturally in the body. It allows some blood vessels to widen by relaxing the thin layer of muscle found in the vessel wall.
Alprostadil, when administered into opening at the end of the penis (urethra), will ultimately cause the penis to become erect by increasing the blood flow into its tissues.
Vitaros cream should be applied to the tip of the penis from the AccuDose container. An erection should result within 5 to 30 minutes.
- Follow your doctor’s instructions and the instructions provided with the medicine.
- Using the AccuDose container, apply Vitaros cream to the tip of the penis. Widen the opening of the penis with one hand. Hold the AccuDose container with the tip just over the opening of the penis with the other hand. Push down the plunger until all of the cream has been removed from the container. DO NOT INSERT THE TIP OF THE ACCUDOSE CONTAINER INTO THE OPENING OF THE PENIS.
- Keep the penis upright for 30 seconds to allow the medication to penetrate. Excess cream may remain on the tip of the penis. Rub this gently into the skin around the opening of the penis with a fingertip.
- Take care to your hands after applying the cream, as it can irritate the eyes if you accidentally touch them.
- Each AccuDose container contains one dose of Vitaros cream. Use it once, then discard it. Replace the cap after use and return it to the sachet to dispose of it.
- An erection will develop in about 5 to 30 minutes after application. The effects can last for one to two hours. Do not exceed one dose in any 24-hour-period.
- Do not exceed two or three doses in any seven days.
- Store the unopened sachets containing the AccuDose containers in a fridge at 2-8ºC. Do not freeze them. They may be kept out of the fridge below 25ºC for up to three days.
Common side effects with Vitaros cream include (may affect more than 1 in 10 patients):
- mild to moderate burning, aching or pain and redness of the penis
- penile oedema
- genital pruritus
- penile tingling, throbbing, numbness, burning
- inflammation of the glans penis (balanitis)
- mild vaginal itching or burning, vaginitis
This effect may be due to the drug or to the act of vaginal penetration. Using a water-based lubricant can help to make vaginal penetration easier.
If you are concerned about these effects, or if the product affects you in a different way, stop using it and talk to your doctor or pharmacist.
Read the following warnings to ensure you are selecting an appropriate product.
Do not use Vitaros:
- if you have disorders such as drop in blood pressure when going from a lying/sitting position to a standing one, history of a heart attack, and syncope (dizziness)
- if you are allergic to alprostadil or any of the other ingredients in this medication
- if you have a condition that might result in a long-lasting erection or a condition such as sickle cell anaemia or trait, polycythemia, thrombocythemia, multiple myeloma, or leukaemia
- if you have an abnormally formed penis
- if you have an inflammation or infection of the penis
- if you are prone to a venous thrombosis
- if you have been told not to have sex for health reasons such as heart problems or a recent stroke
- if you have a hyperviscosity syndrome which could result in a long-lasting erection
- if your partner is pregnant, could become pregnant, or is breastfeeding unless you use a condom barrier.
Talk to your doctor or pharmacist before using Vitaros if you have a history of the
following effects that have been observed with the use of Vitaros:
- prolonged erections lasting >4 hours (priapism)
- symptomatic hypotension (dizziness)
- hepatic and/or renal insufficiency- a lowered dose may be necessary due to impaired metabolism
A condom should be used in the following situations:
- to prevent sexually transmitted diseases
- your partner is pregnant, could become pregnant or is breastfeeding
- during oral sex and anal sex
Only latex condoms have been studied. It is unknown if condoms made of other materials may be damaged by the medication.
Other medicines and Vitaros
Tell your doctor or pharmacist if you take, have recently taken or intend to take any other medications while using Vitaros.
The use of Vitaros with other drugs used to treat Erectile Dysfunction has not been studied. For this reason, if you take other drugs to treat ED, do not combine them with Vitaros. Effects such as dizziness, fainting and prolonged erections could result.
Vitaros has not been tested for use with penile implants or smooth muscle relaxants such as papaverine or drugs used to induce erections such as alpha blocking drugs. There is a risk of painful, prolonged abnormal erection when these drugs are used in combination with Vitaros.
Although unstudied, it is possible that the effects of Vitaros cream may weaken when taken in combination with treatments for high blood pressure, decongestants and appetite suppressants.
If you take drugs to prevent blood clots, do not take Vitaros as you may have an increased risk for bleeding or blood in the urine.
When taken in combination with high blood pressure medication, Vitaros use may increase dizziness and fainting, especially in the elderly.
Please read all packaging and the Product Information Leaflet before taking any new medicine and inform your doctor of medicines you are taking or intend to take.
Each single dosing device of Vitaros cream contains alprostadil 300 micrograms in 100mg of cream.
The other ingredients in the cream are: purified water; ethanol (anhydrous); ethyl laurate;hydroxypropyl guar gum; dodecyl-2-N,N-dimethylaminopropionate hydrochloride; potassium dihydrogen phosphate; sodium hydroxide, for pH adjustment; phosphoric acid, for pH adjustment.