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Vitaros Cream

Vitaros Cream (1 pack - 4 applications)

Sorry, this treatment is currently out of stock.

Vitaros is unavailable from the manufacturer and we have no date when it will be available at this time.

Other ED (Erectile Dysfunction) treatments are available.

Click here to view ED treatments

Description for Vitaros Cream

Vitaros cream is an easy-to-apply, fast-acting topical treatment for erectile dysfunction in men. It is a great option for treating ED where tablets such as Viagra or Cialis have not been effective or are not a desirable solution. Vitaros cream can help to produce a satisfactory erection in as little as five minutes and normally produces an effect for one to two hours.

Product Information

  • Age: 18 Years +

    Maximum per order: 3

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Vitaros cream is an easy-to-apply, fast-acting topical treatment for erectile dysfunction. It is a great option for treating ED where tablets such as Viagra or Cialis have not been effective or are not a desirable solution. Vitaros cream can produce a satisfactory erection in as little as five minutes and normally produces an effect for one to two hours.

Vitaros (alprostadil) is a prescription-only treatment for erectile dysfunction which was launched in the UK in June 2014. Vitaros is available as a cream in individual applicators - there are four applicators in a pack. Vitaros is an alternative treatment for men who have not achieved satisfactory results with tablet treatments (PDE5 inhibitors), or who cannot tolerate the side effects of these tablets.


The active ingredient in Vitaros Cceam is alprostadil, which treats ED in men. It should be applied before sex to achieve an erection in 5 - 30 minutes. Vitaros is easy to apply and may be more convenient than taking a tablet for some men. Because it acts locally, Vitaros cream’s effects normally only last for one to two hours, as opposed to the four to six hours of most tablet ED treatments. This may be ideal for men who only want a short period of action due to side effects or other reasons.

Vitaros cream should be kept in the fridge. It can remain outside of the fridge for up to 72 hours and still retain its effectiveness. Over 72 hours outside of the fridge, however, may make the product less effective and use is not recommended. When you receive Vitaros, you should immediately store it in the fridge to ensure the product remains viable. You can remove it from the fridge on the day of use to apply it at room temperature or to take with you if travelling.

The first time you use Vitaros, it may not be fully effective. Use it for at least four applications on separate occasions before switching treatments. Never apply more than one dose of Vitaros at a time, even if it is ineffective.

Vitaros cream is not a contraceptive and does not protect against sexually transmitted diseases; you should still wear a condom while using Vitaros.

Vitaros cream is generally well-tolerated with few side effects. Most side effects are local and last for one to two hours. For this reason, Vitaros could be a good alternative for men who cannot use ED tablets due to the side effects.

Please read the Patient Information Leaflet before you use Vitaros.

The active ingredient in Vitaros is alprostadil, a prostaglandin. Alprostadil is identical to prostaglandin E1, a chemical that occurs naturally in the body. It allows some blood vessels to widen by relaxing the thin layer of muscle found in the vessel wall.

Alprostadil, when administered into opening at the end of the penis (urethra), will ultimately cause the penis to become erect by increasing the blood flow into its tissues.

Vitaros cream should be applied to the tip of the penis from the AccuDose container. An erection should result within 5 to 30 minutes.


*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.
  • Follow your doctors instructions and the instructions provided with the medicine.
  • Using the AccuDose container, apply Vitaros cream to the tip of the penis. Widen the opening of the penis with one hand. Hold the AccuDose container with the tip just over the opening of the penis with the other hand. Push down the plunger until all of the cream has been removed from the container. DO NOT INSERT THE TIP OF THE ACCUDOSE CONTAINER INTO THE OPENING OF THE PENIS.
  • Keep the penis upright for 30 seconds to allow the medication to penetrate. Excess cream may remain on the tip of the penis. Rub this gently into the skin around the opening of the penis with a fingertip.
  • Take care to thoroughly wash your hands after applying the cream, as it can irritate the eyes if you accidentally touch them.
  • Each AccuDose container contains one dose of Vitaros cream. Use it once, then discard it. Replace the cap after use and return it to the sachet to dispose of it.
  • An erection will develop in about 5 to 30 minutes after application. The effects can last for one to two hours. Do not exceed one dose in any 24-hour-period.
  • Do not exceed two or three doses in any seven days.
  • Store the unopened sachets containing the AccuDose containers in a fridge at 2-8ºC. Do not freeze them. They may be kept out of the fridge below 25ºC for up to three days.

Common side effects with Vitaros cream include (may affect more than 1 in 10 patients):


  • mild to moderate burning, aching or pain and redness of the penis
  • rash
  • penile oedema
  • genital pruritus
  • penile tingling, throbbing, numbness, burning
  • inflammation of the glans penis (balanitis)


Your partner:

  • mild vaginal itching or burning, vaginitis

This effect may be due to the drug or to the act of vaginal penetration. Using a water-based lubricant can help to make vaginal penetration easier.


If you are concerned about these effects, or if the product affects you in a different way, stop using it and talk to your doctor or pharmacist.



Each single dosing device of Vitaros cream contains alprostadil 300 micrograms in 100mg of cream.

The other ingredients in the cream are: purified water; ethanol (anhydrous); ethyl laurate;hydroxypropyl guar gum; dodecyl-2-N,N-dimethylaminopropionate hydrochloride; potassium dihydrogen phosphate; sodium hydroxide, for pH adjustment; phosphoric acid, for pH adjustment.

Read the following warnings to ensure you are selecting an appropriate product.

Do not use Vitaros:

  • if you have disorders such as drop in blood pressure when going from a lying/sitting position to a standing one, history of a heart attack, and syncope (dizziness)
  • if you are allergic to alprostadil or any of the other ingredients in this medication
  • if you have a condition that might result in a long-lasting erection or a condition such as sickle cell anaemia or trait, polycythemia, thrombocythemia, multiple myeloma, or leukaemia
  • if you have an abnormally formed penis
  • if you have an inflammation or infection of the penis
  • if you are prone to a venous thrombosis
  • if you have been told not to have sex for health reasons such as heart problems or a recent stroke
  • if you have a hyperviscosity syndrome which could result in a long-lasting erection
  • if your partner is pregnant, could become pregnant, or is breastfeeding unless you use a condom barrier.


Talk to your doctor or pharmacist before using Vitaros if you have a history of the

following effects that have been observed with the use of Vitaros:

  • prolonged erections lasting >4 hours (priapism)
  • symptomatic hypotension (dizziness)
  • hepatic and/or renal insufficiency- a lowered dose may be necessary due to impaired metabolism
  • fainting



A condom should be used in the following situations:

  • to prevent sexually transmitted diseases
  • your partner is pregnant, could become pregnant or is breastfeeding
  • during oral sex and anal sex

Only latex condoms have been studied. It is unknown if condoms made of other materials may be damaged by the medication.

Other medicines and Vitaros

Tell your doctor or pharmacist if you take, have recently taken or intend to take any other medications while using Vitaros.

The use of Vitaros with other drugs used to treat Erectile Dysfunction has not been studied. For this reason, if you take other drugs to treat ED, do not combine them with Vitaros. Effects such as dizziness, fainting and prolonged erections could result.

Vitaros has not been tested for use with penile implants or smooth muscle relaxants such as papaverine or drugs used to induce erections such as alpha blocking drugs. There is a risk of painful, prolonged abnormal erection when these drugs are used in combination with Vitaros.

Although unstudied, it is possible that the effects of Vitaros cream may weaken when taken in combination with treatments for high blood pressure, decongestants and appetite suppressants.

If you take drugs to prevent blood clots, do not take Vitaros as you may have an increased risk for bleeding or blood in the urine.

When taken in combination with high blood pressure medication, Vitaros use may increase dizziness and fainting, especially in the elderly.

Please read all packaging and the Product Information Leaflet before taking any new medicine and inform your doctor of medicines you are taking or intend to take.

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 3 - 5 day delivery - £2.95
  • Express Tracked Delivery - 1 - 3 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email and in your account.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.



DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Erectile Dysfunction (ED)?

Visit our advice area or contact our support team

Vitaros Cream Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Frequently Asked Questions

  • What is Vitaros cream used for?

    Vitaros cream is used to treat Erectile Dysfunction (impotence).

  • What does Vitaros cream contain?

    Vitaros cream contains the active ingredient alprostadil. Alprostadil is a type of medicine called a prostaglandin.

  • How does Vitaros cream work?

    An erection is caused by a complex chain of events. The nervous system sends signals that trigger the release of active chemicals, which includes prostaglandin E. This chemical causes the blood vessels that enter the penis to widen, and the vessels that exit the penis to constrict. This allows for more blood to enter, whilst stopping blood from leaving the penis. The increased blood flow to the penis causes the erectile tissue to swell, resulting in an erection.

    The active ingredient in Vitaros (alprostadil) is a synthetic form of the naturally occurring chemical prostaglandin E. This chemical plays a pivotal role in the erection process. When administered directly into the urethra (the opening of the penis), alprostadil will widen and constrict the necessary blood vessels, causing the penis to become rigid and erect.    

  • How do I use Vitaros cream?

    Vitaros cream is administered directly into the tip of the penis. To achieve this, open the tip of the penis with one hand whilst holding the Accudose container with the other hand. Position the container just over the opening of the penis and push down on the plunger. This will release the cream from the container. Continue to push down on the plunger until all of the cream has been expelled. Do not insert the tip of the container into the opening of the penis.

    Next, hold the penis in an upright position for 30 seconds. This will allow the cream to penetrate. It is likely that a small amount of excess cream will remain on the tip of the penis. This excess should be gently massaged into the skin around the opening of the penis using a fingertip. After successful application, wash hands thoroughly, as accidental contact with eyes can cause irritation. Each Accudose contains one dose of Vitaros cream. These containers are designed for single use and should be discarded after each use.

    After administration, Vitaros will take between 5 and 30 minutes to take effect. Once an erection has developed, the effects of the medicine should last between 1-2 hours.

    Do not exceed more than one dose in any 24 hour period. Also, do not use more than three doses in any seven day period.

  • How should Vitaros cream be stored?

    An unopened sachet of Vitaros cream should be stored in a fridge between 2-8°C. Vitaros Cream should not be frozen.

    Vitaros cream can be stored out of the fridge, below 25°C, for up to three days. If not used within this time, it should be disposed of.

  • What precautions should I take before and after use?

    Vitaros cream can make some people feel dizzy for up to 2 hours after use. This can potentially affect one’s ability to safely drive or operate heavy machinery. It is advised not to drive or operate machinery until you know whether the medicine will affect you this way 

    When using Vitaros cream, it is recommended to wear a condom during sex. This applies to vaginal, anal, and oral sex. This is because Vitaros can transfer to your partner, causing unwanted side effects, such as vaginal irritation. Vitaros cream does not provide any protection from sexually transmitted infections. Using a condom will help provide this protection.

    If an erection lasts for longer than 4 hours, consult a doctor immediately. A delay in treatment could lead to irreversible damage to the erectile tissue.

    Vitaros cream should be used with extra caution in men who suffer from decreased liver or kidney function.

  • Does Vitaros cream interact with other medicines?

    Before using Vitaro cream, it is important to tell your doctor what medicines you are currently taking. This includes prescriptions medicines, as well as over-the-counter purchases. It should also include any herbal or alternative medicines you are taking. Similarly, check with your doctor or pharmacist before starting any new medicine if you are currently using Vitaros cream.

    Vitaros cream should never be used with any other erectile dysfunction medicine.

    Patients who take medicines for blood clots (anticoagulants) are at greater risk of urethral bleeding after using Vitaros cream.

    Alprostadil can enhance the effects of hypertension medicines. If you take a medicine designed to lower your blood pressure, using Vitaros may make you feel dizzy. If you are affected this way, it is recommended to sit or lie down until these symptoms have passed. Examples of hypertension treatments include:

    • ACE Inhibitors, such as Enalapril, Lisinopril, and Ramipril
    • Calcium channel blockers, such as diltiazem
    • Diuretics, such as bendroflumethiazide and furosemide
    • Alpha-blockers, such as doxazosin
    • Beta-blockers, such as atenolol and propranolol


  • How long does it take to work?

    Vitaros should produce an erection in 5-30 minutes.

  • Can Vitaros cause drowsiness?

    This medication may cause dizziness for up to two hours after its use. For this reason, it could harm your ability to drive or operate machinery safely. Avoid driving or operating machineryuntil you know how this medication affects you and you are certain it won’t affect your performance.

  • Can Vitaros irritate female partners?

    It is recommended that you use a condom during sex, including oral and anal sex, as Vitaros cream may cause side effects, such as vaginal irritation, on your partner.

  • Does it protect against STI’s?

    This medication will not protect you or your partner from sexually transmitted diseases. A condom can provide this protection.

  • How long should an erection last?

    If your erection lasts longer than four hours, consult a doctor immediately. Treatment of this condition should not be delayed longer than six hours, as this can cause damage to the erectile tissue and irreversible erectile dysfunction.

Authored By:

A photo of  Andy Boysan

Andy Boysan


Published on: 02-02-2017

Last modified on: 02-02-2019

Andy is a co-founder, the superintendent pharmacist and director at The Independent Pharmacy.

Reviewed By:

A photo of  William Obeng

William Obeng

MPharm IP

Reviewed on: 02-02-2019

Next review date: 02-02-2021

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