Mirvaso Gel

Mirvaso Gel (30g )

Order before 4pm for delivery from Wed. 29 Mar.

Description for Mirvaso Gel

Mirvaso Gel is one of the most popular choices for treatment of rosacea. It is used once daily to reduce redness associated with rosacea. Mirvaso roascea treatment can be bought from the Online Doctor, following a simple medical questionnaire, and can be delivered quickly and discreetly to a location of your choice. 

Product Information

  • Age: 18 Years +

    Maximum per order: 3

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Mirvaso Gel is available to buy from The Independent Pharmacy Online Doctor service, following a free consultation, to help to treat rosacea. To find out more about rosacea and see all the available treatments, see our Online Doctor Rosacea page.

The active ingredient in Mirvaso gel, Brimonidine Tartrate, belongs to a group of medicines called alpha agonists. These medicines work by stimulating the alpha receptors found in the muscle walls of the blood vessels. When applied topically it causes these blood vessels to contract. This decreases the flow of blood through the vessels, resulting in the reduction of redness.

Mirvaso gel works on a daily basis to reduce facial flushing and redness. If you forget to apply on any given day then the redness for that day will not be reduced. You should not apply double the amount the following day to compensate.

Mirvaso gel is a prescription-only-medicine (POM) that is mainly used to treat the skin condition, rosacea. It contains the active ingredient Brimonidine Tartrate in a 0.33% strength. This means that every gram of Mirvaso gel contains 3.3mg of the active ingredient. Brimonidine Tartrate belongs to a group of medicines called alpha agonists. Mirvaso gel in manufactured by Galderma and comes in a 30g tube. Each tube is accompanied by a comprehensive patient information leaflet. Mirvaso gel is for external use only.

Rosacea is a chronic condition characterised by recurrent episodes of facial flushing, redness and spots. The areas of the face commonly affected are the cheeks, nose, forehead and chin. Rosacea occurs when the blood flow to the facial skin increases. This is due to the small blood vessels in the skin dilating (widening), allowing for an increase in blood flow.


How to apply Mirvaso Gel

  • Mirvaso Gel is applied ONCE daily, at any time of day, for as long as facial erythema (redness) is present.
  • Apply a pea-sized amount to the forehead, nose, chin and cheeks.
  • Spread smoothly and evenly as a thin layer across the entire area avoiding the eyes, eyelids, lips, mouth and membrane of the inner nose. Mirvaso should only be applied over the face.
  • Wash your hands immediately after applying. 
  • The maximum daily recommended dose is 1g in total weight (five pea sized amounts)

Mirvaso can be used in conjunction with other gels and creams for the treatment of rosacea (such as Rozex). It can also be used with makeup and cosmetics. They should only be used after the applied Mirvaso has dried into your skin.

Like all medicines, Mirvaso can cause side effects, although not everybody gets them. Side effects that are considered to be common include:

  • Redness
  • Itching
  • Flushing
  • Skin burning sensation

They are typically mild to moderate in severity, and usually do not require Mirvaso use to be stopped. These side effects can feel like a worsening of your initial symptoms, and it is impossible to predict if you will experience them before you try Mirvaso. For this reason, we recommend that you order just one tube to start with, and use the gel on a small area of the face at first. Unfortunately we are not able to offer a refund for the product if you experience this common and documented side effect.

Less common side effects experienced when using Mirvaso gel include:

  • Acne
  • Dry mouth
  • Feeling cold in hands and feet
  • Feeling hot
  • Headache
  • Nasal congestion
  • Skin rash, skin pain or discomfort, skin irritation or inflammation, dry skin, warm skin sensation, tingling or sensation of pins and needles
  • Swelling of the eyelid or face
  • Urticaria (itching)
  • Worsening of rosacea

Always ensure you read the patient information leaflet enclosed with Mirvaso before using the gel.

  • Keep out of the reach and sight of children.
  • Not to be used in children less than 18 years.
  • Do not use if you are allergic to any of the listed ingredients.
  • Do not apply to closed eyes.
  • Mirvaso has not been studied in patients with renal or hepatic impairment.
  • Mirvaso should not be used during pregnancy or breast feeding.

Mirvaso is not suitable for use if you suffer with any of the following conditions:

  • The skin of your face is irritated or has open wounds.
  • You have problems with your heart or circulation.
  • You have depression, decreased blood flow to the brain or the heart, fall in blood pressure on standing up, decreased blood flow to the hands, feet or skin, or Sjögren’s syndrome (a chronic disease in which the body’s natural defence - the immune system - attacks the moisture-producing glands).
  • You have kidney or liver problems or have had them in the past.

Mirvaso is not suitable for use if you take any of the following:

  • Medicines used for depression or Parkinson’s disease including so?called monoamine oxidase (MAO) inhibitors (for example selegiline or moclobemide)
  • Tricyclic antidepressants (such as imipramine) or tetracyclic antidepressants (such as maprotiline, mianserin or mirtazapin).
  • Medicines used for the treatment of pain, sleep disorders, or anxiety disorders.
  • Medicines used for the treatment of psychiatric disorders (chlorpromazine) or used for hyperactivity (methylphenidate) or used for high blood pressure (reserpine).
  • Medicines which act on the same body mechanism as Mirvaso (other alpha agonists, e.g. clonidine; so?called alpha blockers or alpha antagonists, e.g. prazosin, isoprenaline which are most often used for treatment of high blood pressure, slow heart rate or asthma).
  • Cardiac glycosides (e.g. digoxin), used to treat heart problems.
  • Blood pressure lowering medicines such as beta-blockers or calcium channel blockers (e.g. propranolol, amlodipine).

Mirvaso Gel contains Brimonidine Tartrate 0.33% as the active ingredient.

Mirvaso Gel also contains: Carbomer, Methylparahydroxybenzoate (E218), Phenoxyethanol, Glycerol, Titanium Dioxide, Propylene Glycol, Sodium Hydroxide, Purified Water.

Need to know more about Rosacea?

Visit our advice area or chat online to our support team

Frequently Asked Questions

  • What is Mirvaso?

    Mirvaso gel is the only licensed product available to treat redness and flushing in rosacea. It contains the active ingredient brimonidine. It starts to work in as little as 30 minutes and lasts for up to 12 hours. Mirvasoi is effective at reducing redness in 70% of patients suffering from rosacea. It can be used by patients of any age over 18 years old and it is just as effective for teenagers and the elderly alike.

  • How does Mirvaso work?

    The symptoms of rosacea can include facial redness (around the central part of the face), swollen blood vessels on the nose and skin, and tender bumps and lumps on the skin, which can be hot and tender to touch. These symptoms are believed to be caused by the dilation of blood vessels and increased blood flow to the area.

    Mirvaso constricts or narrows the blood vessels, which reduces the blood flow and therefore reduces the symptoms of rosacea.

    You can also help to keep the symptoms under control by using by using these self-help techniques.

  • How do I apply Mirvaso?

    Apply Mirvaso gel once daily to dry skin (application to wet skin can cause the gel to run in to the eyes or mouth).

    Using a clean fingertip, apply one small pea-sized amount of gel to each of the following affected areas - forehead, both cheeks, nose and chin - up to five in total.

    Allow the gel to dry before applying make up or other cosmetics.

    Take special care when applying around the eyes. If any gel gels in the eyes it should be washed out thoroughly with water straight away.

    Wash your hands after use to limit the constriction of blood vessels in the hands and fingers.

  • What’s the difference between Mirvaso and other Rosacea treatments?

    There are multiple treatments for rosacea that are split into two distinct groups - one to reduce the symptoms of redness and flushing, and the other to fight the infection on the skin that often causes rosacea. The groups and treatments are compared below:

    Papules and pustulesThese are lumps and bumps on the surface of the skin which may be red, hot and tender to touch. They are normally caused by bacteria that live on the skin.

    Azelic Acid and Metronidazole are used to treat mild to moderate pustules and papules. They are applied once or twice a day. The Azelaic Acid is more effective but comes with a greater incidence of side effects. Treatment needs to be continued for a few weeks before a significant difference is usually seen.

    Erythromycin (antibiotic) is used to treat papules and pustules which are greater in number and severity and unresponsive to other medicines. It is also used when there is inflammation. Erythromycin needs to be taken for 4 - 6 weeks before a significant difference is seen. 

    Facial redness and flushing - symptoms caused by expanded blood vessels.

    Mirvaso reduces the blood flow thought to be responsible for the redness and flushing. When it is applied once a day a difference can be seen in as little as 30 minutes, lasting for up to 12 hours. Some patients may experience a worsening of the redness, usually within the first 2 weeks of treatment. If you stop using the gel this will get better by itself. You should test a small portion of the skin with the gel before restarting and if it occurs again the treatment should be discontinued.

    Oral Treatments – Clonidine, beta-blockers and anxiety medication prescribed under the supervision of a dermatologist can reduce redness and flushing. The mode of action in reducing rosacea symtpoms remains unclear.

    Thickened Skin

    This usually occurs on the nose (rhinophyma) and if severe can be treated with surgery, derma abrasion or laser treatment.

  • Is it safe to use Mirvaso continuously?

    Mirvaso can be used continuously. It needs to be used every day for the redness and flushing to be controlled.

  • What are the side effects of Mirvaso?

    Very little Mirvaso gel is absorbed in to the blood stream and circulated around the body. It is applied in smaller amounts where it is needed, therefore it is well tolerated and most of the side effects occur where the gel is applied.

    Some patients find that the gel makes the redness worse (this may be coupled with itching and burning sensation too). This usually happens within the first 2 weeks of treatment. If this happens stop the gel and treat accordingly with painkillers and antihistamines where necessary.

    Test using a small amount of gel before restating treatment. Discontinue if the redness worsens again.

    Mirvaso may also cause acne, dry mouth and cold feeling in the hands and feet in less than 1% of users.

  • How long will it take for Mirvaso work?

    Mirvaso will start to work in as little as 30 minutes and lasts for up to 12 hours.

  • What do you do if you miss an application?

    The effects of Mirvaso last for up to a day. It needs to be applied daily to be effective. If you miss an application you won't experience any reduced redness for that day.

    Do not apply two or more applications in a day as this increases the chance of side effects without an increase in a reduction in redness.

  • Can I use Mirvaso and make up together?

    Apply Mirvaso gel as usual and allow to dry completely before applying make up and other cosmetics (including camouflage creams like Veil cover cream). As long as Mirvaso has had time to absorb into the skin there is no problem applying make up or cosmetics over the top.

  • Is there anyone who should not use Mirvaso?

    • Patients who are pregnant or breast-feeding should not use Mirvaso because it may affect development of the unborn baby. The concentration of Mirvaso in breast milk has not been established.
    • Mirvaso does not have any effect on fertility.
    • Mirvaso is not to be used by patients under the age of 18 years old.
    • Mirvaso should not to be used by patients with liver or kidney problems as the effects have not been established.
    • Do not use on irritated or open/broken skin.
    • Patients with poor circulation in their hands and feet or with low blood pressure or a tendency for their blood pressure to fall should not use Mirvaso gel.
  • Can I use Mirvaso with other medication?

    Mirvaso should not be taken with the following medication:

    • Antidepressants called Mono Amine Oxidase Inhibitors or MAOI for short
    • Imipramine and other tricyclic anti depressants
    • Moclobemide and maprotiline used to treat depression (not very commonly used in the UK)
    • Medication used to treat Parkinson’s, namely selegeline.
    • (If you are not sure what type of antidepressant medication you are taking, then contact us or talk to your doctor.)
    • Chlorpromazine used to treat psychiatric disorders.
    • Methylphenidate for the treatment of hyperactivity.
    • Reserpine for high blood pressure (not commonly used in the UK).
    • Digoxin and other cardiac glycosides used in treating heart failure.
    • Propranolol and other beta-blockers for treating high blood pressure.
    • Amlodipine and other calcium channel blocker commonly used to treat high blood pressure.
    • Alpha agonist drugs like clonidine.
    • Alpha blocking drugs like prazosin used for treating high blood pressure, asthma or a slow heart rate.
  • Is there an unbranded version of Mirvaso?

    Galderma, the manufacturers of Mirvaso, are currently the only licensed manufacturers of the brimonidine gel in the UK. As the patent for this product has not yet expired, there is no unbranded or generic alternate on the UK market.

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