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Mirvaso Gel

Mirvaso Gel (30g )

Order before 3pm for delivery from Fri. 30 Jul and Mon. 02 Aug.

Description for Mirvaso Gel

Mirvaso topical gel is one of the most popular forms of rosacea treatment. It is used once daily to reduce redness associated with rosacea. Mirvaso rosacea treatment can be bought from the Independent Pharmacy following a simple medical questionnaire being approved by our doctors and can be delivered quickly and discreetly to a location of your choice. 

Save money on topical medication for rosacea by purchasing online. Delivery is free over £40, otherwise, costs are found below. You cannot buy this form of rosacea treatment over the counter. Obtain a rosacea cream prescription from your doctor or through The Independent Pharmacy.

Mirvaso Gel Information

  • Age: 18 Years +

    Maximum per order: 3

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

What is Mirvaso?

Mirvaso face cream for redness is available to buy from The Independent Pharmacy’s online doctor service to help to treat rosacea, following a free consultation. To find out more about rosacea and see all the available treatments, see our rosacea advice page.

The active ingredient in Mirvaso rosacea gel, brimonidine tartrate, belongs to a group of medicines called alpha agonists. Mirvaso is the brimonidine brand name. These medicines work by stimulating the alpha receptors found in the muscle walls of the blood vessels. When applied topically, it causes these blood vessels to contract. This decreases the flow of blood through the vessels, resulting in the reduction of redness.


Topical treatment for rosacea 

Mirvaso gel is topical rosacea treatment that works on a daily basis to reduce facial flushing and redness. If you forget to apply on any given day, then the redness for that day will not be reduced. You should not double the amount the following day to compensate.

Mirvaso gel is a prescription-only medicine that is mainly used to treat rosacea. It contains the active ingredient brimonidine tartrate at 0.33%. This means that every gram of Mirvaso gel contains 3.3mg of the active ingredient. Topical Mirvaso gel is manufactured by Galderma and comes in a 30g tube. Each tube is accompanied by a comprehensive patient information leaflet. Mirvaso gel is for external use only. It can also be found by searching for brimonidine gel uk.

Rosacea is a chronic condition characterised by recurrent episodes of facial flushing, redness and spots. The areas of the face commonly affected are the cheeks, nose, forehead and chin. Rosacea occurs when the blood flow to the facial skin increases. This is due to the small blood vessels in the skin dilating, allowing for an increase in blood flow.

There’s no set cure for rosacea: it all depends on the severity of your symptoms. Those with more severe symptoms may be prescribed an oral antibiotic to reduce inflammation. The antibiotics commonly used to treat rosacea include tetracycline, oxytetracycline, doxycycline and erythromycin. Red face treatments – such as rosacea cream and topical brimonidine – also help to keep the symptoms under control.

It helps to know your triggers. Direct sunlight, for example, can often make symptoms worse – as can wearing too much makeup or using harsh skincare products. Rosacea sufferers should take care to avoid other potential triggers, such as emotional stress, alcohol, spicy foods, hot baths, extreme weather and caffeine withdrawal. 

Rosacea tends to appear in stages, starting with pre-rosacea, where the skin is slightly red or flushed in appearance. This can develop into inflammatory rosacea, where alongside redness you may also experience pustules, red bumps and cysts. The third stage is vascular rosacea, where the sufferer may experience swelling of the nose and cheeks, and the skin can become especially sensitive. Topical cream for rosacea is usually prescribed at first sign of symptoms.

Rosacea typically has four subtypes: erythematotelangiectatic rosacea, papulopustular rosacea, phymatous rosacea, and ocular rosacea. Erythematotelangiectatic and papulopustular rosacea are characterised by redness, visible blood vessels and acne-like breakouts. Phymatous rosacea is where the skin becomes thicker, and has an almost bumpy texture. By contrast, ocular rosacea occurs only on the eyelids.

Mirvaso Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.5303.pdf

*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

How to apply Mirvaso gel

  • Mirvaso topical gel is applied once daily at any time of day, for as long as facial erythema (redness) is present
  • Apply a pea-sized amount to the forehead, nose, chin and cheeks
  • Spread a thin layer smoothly and evenly across the entire area, avoiding the eyes, eyelids, lips, mouth and membrane of the inner nose. Mirvaso should only be applied over the face
  • Wash your hands immediately after applying
  • The maximum daily recommended dose is 1g in total weight (five pea-sized applications)

Mirvaso can be used in conjunction with other rosacea creams, such as Rozex. It can also be used with makeup and cosmetics. They should only be used after the applied Mirvaso has been absorbed into your skin.

Brimonidine side effects

Like all medicines, Mirvaso can cause side effects, although not everybody gets them. Common side effects include:

  • Redness
  • Itching
  • Flushing
  • Skin burning sensation

They are typically mild to moderate in severity, and usually do not require Mirvaso use to be stopped. These side effects can feel like a worsening of your initial symptoms, and it is impossible to predict if you will experience them before you try Mirvaso. For this reason, we recommend that you order just one tube to start with, and use the gel on a small area of the face at first.

Less common side effects include:

  • Acne
  • Dry mouth
  • Cold hands and feet
  • Feeling hot
  • Headache
  • Nasal congestion
  • Skin rash, pain or inflammation
  • Dry skin
  • Warm tingling sensation
  • Swelling of the eyelids or face
  • Urticaria (itching)
  • Worsening of rosacea

Mirvaso gel ingredients

Mirvaso rosacea gel contains brimonidine tartrate 0.33% as the active ingredient. This is a common form of medication for rosacea redness.

Mirvaso ointment for rosacea also contains: 

  • Carbomer
  • Methyl parahydroxybenzoate (E218)
  • Phenoxyethanol
  • Glycerol
  • Titanium dioxide
  • Propylene glycol
  • Sodium hydroxide
  • Purified water

Mirvaso gel warnings

Mirvaso gel is a prescription medication for rosacea. Always ensure you read the patient information leaflet enclosed with Mirvaso before using the gel. You will need a rosacea prescription in order to buy Mirvaso gel online.

  • Keep out of the reach and sight of children
  • Not to be used in children less than 18 years
  • Do not use if you are allergic to any of the listed ingredients
  • Do not apply to closed eyes
  • Mirvaso has not been studied in patients with renal or hepatic impairment
  • Mirvaso should not be used during pregnancy or breastfeeding

Mirvaso is not suitable for use if you suffer with any of the following conditions:

  • The skin of your face is irritated or has open wounds
  • You have problems with your heart or circulation
  • You have depression, decreased blood flow to the brain or the heart, fall in blood pressure on standing up, decreased blood flow to the hands, feet or skin, or Sjögren’s syndrome
  • You have kidney or liver problems or have had them in the past

Mirvaso is not suitable if you take any of the following:

  • Medicines used for depression or Parkinson’s disease, including monoamine oxidase (MAO) inhibitors
  • Tricyclic antidepressants (such as imipramine) or tetracyclic antidepressants (such as maprotiline, mianserin or mirtazapine)
  • Medicines used for the treatment of pain, sleep disorders, or anxiety disorders
  • Medicines used for the treatment of psychiatric disorders (chlorpromazine) or used for hyperactivity (methylphenidate) or for high blood pressure (reserpine)
  • Medicines that act on the same body mechanism as Mirvaso (other alpha agonists)
  • Cardiac glycosides (e.g. digoxin) used to treat heart problems
  • Blood pressure lowering medicines such as beta-blockers or calcium channel blockers (e.g. propranolol, amlodipine)

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2 - 3 day delivery - £2.95
  • Express Tracked Delivery - 1 - 2 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail & DPD orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email, in your online account and from any notifications from your courier.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail


  • Fully tracked delivery
  • SMS & email notifications
  • Four-hour delivery window
  • Change delivery date directly with Royal Mail
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local Post Office or Royal Mail Customer Service Point.

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.




  • Fully tracked delivery
  • SMS & email notifications
  • One-hour delivery window
  • Change delivery date directly with DPD
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local collection point.

DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Rosacea?

Visit our advice area or contact our support team

Mirvaso Gel Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Frequently Asked Questions

  • What is Mirvaso gel?

    Mirvaso gel is the only licensed product available to treat redness and flushing in rosacea. It contains the active ingredient brimonidine. It starts to work in as little as 30 minutes and lasts for up to 12 hours. Mirvaso is effective at reducing redness in 70% of patients suffering from rosacea. It can be used by patients of any age over 18 years old and it is just as effective for teenagers and the elderly alike.

  • How does Mirvaso work?

    The symptoms of rosacea can include facial redness (around the central part of the face), swollen blood vessels on the nose and skin, and tender bumps and lumps on the skin, which can be hot and tender to touch. These symptoms are believed to be caused by the dilation of blood vessels and increased blood flow to the area.

    Mirvaso constricts or narrows the blood vessels, which reduces the blood flow and therefore reduces the symptoms of rosacea.

    You can also help to keep the symptoms under control by using by using these self-help techniques.

  • How do I apply Mirvaso rosacea gel?

    Apply Mirvaso gel once daily to dry skin (application to wet skin can cause the gel to run into the eyes or mouth).

    Using a clean fingertip, apply one small pea-sized amount of gel to each of the following affected areas - forehead, both cheeks, nose and chin - up to five in total.

    Allow the gel to dry before applying makeup or other cosmetics.

    Take special care when applying around the eyes. If any gel gels in the eyes it should be washed out thoroughly with water straight away.

    Wash your hands after use to limit the constriction of blood vessels in the hands and fingers.

  • What’s the difference between Mirvaso and other rosacea treatment?

    There are multiple treatments for rosacea that are split into two distinct groups - one to reduce the symptoms of redness and flushing, and the other to fight the infection on the skin that often causes rosacea. The groups and treatments are compared below:

    Papules and pustulesThese are lumps and bumps on the surface of the skin which may be red, hot and tender to touch. They are normally caused by bacteria that live on the skin.

    Azelaic Acid and Metronidazole are used to treat mild to moderate pustules and papules. They are applied once or twice a day. The Azelaic Acid is more effective but comes with a greater incidence of side effects. Treatment needs to be continued for a few weeks before a significant difference is usually seen.

    Erythromycin (antibiotic) is used to treat papules and pustules which are greater in number and severity and unresponsive to other medicines. It is also used when there is inflammation. Erythromycin needs to be taken for 4 - 6 weeks before a significant difference is seen. 

    Facial redness and flushing - symptoms caused by expanded blood vessels.

    Mirvaso reduces the blood flow thought to be responsible for the redness and flushing. When it is applied once a day a difference can be seen in as little as 30 minutes, lasting for up to 12 hours. Some patients may experience a worsening of the redness, usually within the first 2 weeks of treatment. If you stop using the gel this will get better by itself. You should test a small portion of the skin with the gel before restarting and if it occurs again the treatment should be discontinued.

    Oral Treatments – Clonidine, beta-blockers and anxiety medication prescribed under the supervision of a dermatologist can reduce redness and flushing. The mode of action in reducing rosacea symptoms remains unclear.

    Thickened Skin

    This usually occurs on the nose (rhinophyma) and if severe can be treated with surgery, dermabrasion or laser treatment. Laser treatment involves having narrow lasers aimed at the visible blood vessels in the skin, causing them to shrink so they're no longer visible. It can be mildly painful, with possible side effects including temporary bruising and swelling.

  • Is it safe to use Mirvaso gel continuously?

    Mirvaso can be used continuously. It needs to be used every day for the redness and flushing to be controlled.

  • What are the side effects of Mirvaso?

    Very little Mirvaso gel is absorbed into the bloodstream and circulated around the body. It is applied in smaller amounts where it is needed, therefore it is well tolerated and most of the side effects occur where the gel is applied.

    Some patients find that the gel makes the redness worse (this may be coupled with itching and burning sensation too). This usually happens within the first 2 weeks of treatment. If this happens stop the gel and treat accordingly with painkillers and antihistamines where necessary.

    Test using a small amount of gel before restarting treatment. Discontinue if the redness worsens again.

    Mirvaso may also cause acne, dry mouth and cold feeling in the hands and feet in less than 1% of users.

  • How long will it take for Mirvaso gel to work?

    Mirvaso will start to work in as little as 30 minutes and lasts for up to 12 hours.

  • What do you do if you miss an application?

    The effects of Mirvaso last for up to a day. It needs to be applied daily to be effective. If you miss an application you won't experience any reduced redness for that day.

    Do not apply two or more applications in a day as this increases the chance of side effects without an increase in a reduction in redness.

  • Can I use Mirvaso and make up together?

    Apply Mirvaso gel as usual and allow to dry completely before applying makeup and other cosmetics (including camouflage creams like Veil cover cream). As long as Mirvaso has had time to absorb into the skin there is no problem applying makeup or cosmetics over the top.

  • Is there anyone who should not use Mirvaso rosacea gel?

    • Patients who are pregnant or breast-feeding should not use Mirvaso because it may affect development of the unborn baby. The concentration of Mirvaso in breast milk has not been established.
    • Mirvaso does not have any effect on fertility.
    • Mirvaso is not to be used by patients under the age of 18 years old.
    • Mirvaso should not to be used by patients with liver or kidney problems as the effects have not been established.
    • Do not use on irritated or open/broken skin.
    • Patients with poor circulation in their hands and feet or with low blood pressure or a tendency for their blood pressure to fall should not use Mirvaso gel.
  • Can I use Mirvaso with other medication?

    Mirvaso should not be taken with the following medication:

    • Antidepressants called Monoamine Oxidase Inhibitors or MAOI for short
    • Imipramine and other tricyclic antidepressants
    • Moclobemide and maprotiline used to treat depression (not very commonly used in the UK)
    • Medication used to treat Parkinson’s, namely selegiline.
    • (If you are not sure what type of antidepressant medication you are taking, then contact us or talk to your doctor.)
    • Chlorpromazine used to treat psychiatric disorders.
    • Methylphenidate for the treatment of hyperactivity.
    • Reserpine for high blood pressure (not commonly used in the UK).
    • Digoxin and other cardiac glycosides used in treating heart failure.
    • Propranolol and other beta-blockers for treating high blood pressure.
    • Amlodipine and other calcium channel blocker commonly used to treat high blood pressure.
    • Alpha agonist drugs like clonidine.
    • Alpha blocking drugs like prazosin used for treating high blood pressure, asthma or a slow heart rate.
  • Is there an unbranded version of Mirvaso gel?

    Galderma, the manufacturers of Mirvaso, are currently the only licensed manufacturers of the brimonidine gel in the UK. As the patent for this product has not yet expired, there is no unbranded or generic alternate on the UK market.

  • Rosacea and couperose: what’s the difference?

    The two skin conditions can appear very similar. The main difference is that couperose occurs due to the capillary walls expanding, whereas rosacea is an inflammation of the skin. However, some rosacea sufferers may experience couperose skin as an initial symptom. Prevalence of couperose is usually down to sun exposure, extreme temperatures and lifestyle habits, such as smoking and drinking alcohol.

  • Can changing your diet improve rosacea?

    Certain dietary changes may help to reduce the symptoms of rosacea. It’s a good idea to avoid trigger foods and drinks, including certain vegetables, alcohol, caffeine, citrus fruits, refined sugar, beef and seafood. Some vitamins and minerals also have anti-inflammatory effects – seek professional advice before adding supplements to your diet. 

  • Do I have rosacea or dermatitis seborreica?

    Seborrheic dermatitis is also an inflammatory skin disorder, and most commonly appears inside the ears, on the forehead, in the eyebrows, and around the nose. It’s characterised by scaly/greasy/yellow patches of skin and is often accompanied by dandruff – but no acne bumps or pustules, as with rosacea.

    If you’re uncertain what you’re suffering from, get a free online consultation and we’ll help to identify your condition. Often, people with rosacea also have seborrheic dermatitis, and these different conditions must be treated separately. If you’re only suffering from dermatitis, you will likely be prescribed a treatment like E45 Itch Relief Cream or Dermol Cream.

  • What Is Brimonidine Gel?

    Mirvaso is the brand name for the active Ingredient brimonidine.

Authored By:

A photo of  Scott McDougall

Scott McDougall


Published on: 02-02-2017

Last modified on: 02-02-2021

Scott is one of the two founders of The Independent Pharmacy. He is a registered pharmacist and the registered manager of our service with the CQC.

Reviewed By:

A photo of Dr Donald Grant

Dr Donald Grant

MB ChB DRCOG MRCGP Dip.orth.med

Reviewed on: 02-02-2021

Next review date: 02-02-2023

Dr Don Grant is a GP with over 30 years experience and is the Clinical Advisor at The Independent Pharmacy

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