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Buy Synphase Tablets online

Synphase Tablets (3 x 21 tablets)

Order before 4pm for delivery from Tue. 24 Jul.

Description for Synphase Tablets

Buy repeat supplies of Synphase tablets online with a quick, easy, free online consultation. Phasic 21-day contraceptive pills, like Synphase, contain a combination of the hormones oestrogens and progestogens. They help to make it harder for the sperm to penetrate the womb and to reduce the chance of a fertilised egg implanting in the womb. If taken correctly they are over 99% successful at preventing pregnancy.

Product Information

  • Age: 18 years +

    Maximum per order: 2

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Synphase is an oral contraceptive. It is a triphasic combined pill. When used correctly, it will provide near 100% protection against pregnancy. Its two active ingredients, norethisterone and ethinylestradiol, prevent ovulation from occurring during the menstrual cycle. Synphase is 'triphasic' in that it alters the amount of norethisterone in one dose, depending on the point in the cycle. This more closely mimics the natural hormonal cycle, which reduces some of the side effects associated with many other oral contraceptives.

Synphase can be purchased online from The Independent Pharmacy, following a simple medical questionnaire. One of our doctors will review your order on the same working day - if they deem that Synphase is suitable for you, your order will be with you as soon as the next working day.

Pregnancy occurs when an egg released from the ovaries is fertilised by sperm. In a normal menstrual cycle, the ovaries release one egg each month - this is the process of ovulation. This process is controlled by the female sex hormones progesterone and oestrogen. Synphase contains two synthetic hormones, norethisterone and ethinylestradiol, which imitate these two natural hormones. They control the levels of each hormone in such a way that prevents an egg from being released. The Pill also makes it more difficult for sperm to reach the uterus, by thickening the fluid that is in the cervix.

During a regular menstrual cycle, the endometrium (the wall of the uterus) builds up in preparation for a fertilised egg. Synphase reduces the extent of this buildup, making it less likely that a fertilised egg will develop into an embryo. As a further result, periods become lighter. The biphasic course of norethisterone in Synphase reduces side effects by more closely imitating the natural hormonal cycle.

There are 21 Synphase pills in a pack. Once you have finished a pack, you will stop taking the pill for seven days. During this time you will have a normal bleed. Once seven days have passed, begin your next cycle of treatment.

Non-Medicinal Contraception Alternatives

  • Female Condoms- Not only do they prevent pregnancy they also prevent STIs. There is currently only one brand available in the UK, called Femidom. Shown to be 95% effective. 
  • Male Condoms- Prevent pregnancy and also prevent STIs. Shown to be 98% effective. 
*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

If possible, begin taking Synphase on the first day of your period. Take one pill at a similar time each day, in the indicated order.

For the first seven days, you will take blue tablets which contain 0.5mg norethisterone. For the next nine days you will take white tablets which contain 1mg norethisterone. For the final five days you will take blue tablets again.

There are 21 Synphase pills in a pack. Once you have finished a pack, you will stop taking the pill for seven days. During this time you will have a normal bleed. Once seven days have passed, begin your next cycle of treatment.

If you forget to take a dose, take it as soon as you remember, even if it is nearly time for your next pill. If you have missed one day, you should still be protected from pregnancy. If you miss multiple days, you are advised to use additional contraception for the following seven days.

Not everyone will experience side effects when they take Synphase, however if you do they may include:

Nausea, weight gain, change in appetite, change in libido, headaches, increased blood pressure, depression, irregular periods, breast pain

If you are concerned about these effects, or if the product affects you in any other way, stop using it and talk to your doctor or pharmacist.

The active ingredients contained in Synphase are:

Blue tablets - 0.5mg norethisterone, 35mcg ethinylestradiol

White tablets - 1mg norethisterone, 35mcg ethinylestradiol

Synphase also contains the following inactive ingredients to make up the complete product:

Maize starch, polyvidone, lactose, magnesium stearate. The blue pills also contain the colouring E132.

Reading the following warnings carefully will help to ensure you are selecting an appropriate product.

Synphase is unsuitable for you if you have:

  • An allergy to any of the ingredients of Synphase
  • A history of heart attack or stroke
  • A family history of blood clots
  • A blood clotting disorder
  • High fat levels in the blood
  • Any history of cancer of the breast, vagina, cervix or uterus
  • Unexplained vaginal bleeding
  • Severe migraines
  • Severe liver disease

Synphase is unsuitable for you if you have suffered from any of the following problems while pregnant:

  • Jaundice
  • Pemphigoid gestationis (a rash involving blisters of the hands and feet)
  • Pruritus

You may be advised not to take Synphase if you suffer from any of the following conditions:

  • Migraines
  • Epilepsy
  • Cardiovascular disease
  • Asthma
  • High blood pressure
  • Kidney disease
  • Multiple sclerosis
  • Diabetes
  • Impaired liver function
  • Varicose veins
  • Any breast problems
  • Depression
  • Fibroids
  • Muscle problems
  • Irregular periods
  • Gallsones
  • Sickle-cell anaemia
  • Chloasma
  • Porphyria
  • Otosclerosis

Do not use Synphase if you have breast cancer, or if you have had it before. Long-term use of hormonal contraceptives may slightly increase your chance of developing breast cancer. Once you have stopped using the Pill for at least 10 years, your risk levels will come back down. Women who are elderly and/or overweight are more vulnerable to breast cancer. Take care using Synphase if a close relative has suffered from breast cancer before. Check your breasts and nipples regularly for any changes or lumps. If you notice anything abnormal, visit your doctor as soon as you can.

You may be more susceptible to blood clots while taking Synphase, especially during the first year of use. Talk to your GP before having any operation while taking the Pill. You may need to stop using Synphase in advance of the operation to avoid the increased risk of a blood clot. You are also at a heightened risk of developing a blood clot if you:

  • Smoke
  • Are obese
  • Have a family history of blood clots
  • Do not exercise regularly
  • Have had a miscarriage in the past
  • Have recently given birth

Synphase may increase your chance of developing cervical cancer. For this reason, you should have regular smear tests while taking the Pill.

If you require any blood test, inform your doctor of which medicines you are taking - Synphase may alter the results of some blood tests.

The following medicines may impact the effectiveness of Synphase:

  • Epilepsy medicines (e.g. carbamazepine, phenytoin)
  • St John's Wort
  • HIV medicines (e.g. nelfinavir, ritonavir)
  • Certain antibiotics (e.g. rifabutin, rifampicin)
  • Certain antifungal medicines (e.g. griseofulvin)
  • Modafinil

Please read all packaging and the Product Information Leaflet before taking any new medicine and inform your doctor of medicines you are taking or intend to take.


We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2/3 day delivery - £2.95
  • Express Tracked Delivery - 1/2 day delivery - £4.45
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

All our orders are sent out using Royal Mail. We always aim to dispatch all orders received before 4pm the same working day. Any orders received after 4pm or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders can be fully tracked in your account.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 5.30pm the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 5.30pm to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 5.30pm to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.



We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Contraceptive Pill?

Visit our advice area or contact our support team

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Frequently Asked Questions

  • When should I start taking Synphase?

    If possible, begin taking Synphase on the first day of your period. If you begin taking the Pill in the first five days of your cycle, you will be immediately protected from pregnancy. If you begin later in your cycle, you will need to abstain from sex or use alternative contraception for the first seven days of taking Synphase.

    If you have a menstrual cycle of less than 24 days, you may need to use alternative contraception for your first seven days regardless of when you start.

    If you have just given birth, begin taking Synphase on day 21 following the birth. If you begin taking the Pill later than this, you will not be immediately protected against another pregnancy.

    Begin taking Synphase immediately following an abortion or miscarriage. If more than seven days have passed, you will need to use additional contraception for your first seven days of using the Pill.

  • I have missed the first pill in a packet. Will Synphase still be effective?

    It is especially important to use Synphase correctly in the first week of a packet. If you took your pills in the previous packet correctly, you should be protected from pregnancy so long as you have only missed one pill in your first week.

  • Is it common to notice spotting following a missed pill?

    This is to be expected, especially for a combined pill such as Synphase. The spotting may continue until the end of your current packet of pills, but you will still be protected from pregnancy so long as you only skipped one pill. Following your pill break, everything should revert to normal.

  • Is it common to have a late period following a missed pill?

    It is fairly common to have a delayed period while on a contraceptive pill. If you have been taking Synphase correctly, there should be no concern. If, however, your period is late and you have recently missed a pill, you may want to confirm that you are not pregnant.

  • What should I do if I have missed three or more pills?

    This will depend on which stage of a packet you are at when you skip the pills. If it is from the first week of a packet, you will not have been protected from pregnancy. If you have had unprotected sex, you may want to pursue emergency contraception. If you are on the last week of a pack, you will likely be protected so long as you start your next pack without a pill break.

    Otherwise, if you have been using Synphase correctly, you should not need to worry about your protection during the three days that you missed. However, you will need to use additional contraception for one week alongside your daily pill before you are completely protected again.

  • Will having diarrhoea affect my protection?

    Mild diarrhoea will not affect the effectiveness of Synphase. If you have had severe diarrhoea, or if you are unsure, you may want to use additional contraception for seven days to ensure that you will remain protected.

  • Is it safe to drink while taking Synphase?

    Yes, it is safe to drink while taking Synphase

  • Is it safe to drive while taking Synphase?

    It is safe to drive unless you have noticed side effects such as drowsiness which may affect your driving.

  • How do I store Synphase?

    Synphase should be stored somewhere that is below 25°C, dry and away from direct sunlight.

  • What does this pill contain?

    Synphase contains ethinylestradiol, norethisterone, Maize starch, polyvidone, lactose and magnesium stearate. The blue pills also contain the colouring E132. Do not use Synphase if you are allergic to any of this pill’s ingredients.

  • Can I use Synphase while pregnant?

    It is advised not to use this contraceptive while pregnant or breastfeeding.

  • Is Synphase available for next-day delivery?

    Yes – we understand that sometimes you will want your treatment as soon as possible. If ordered before 4pm Monday to Friday, Synphase is available for next-day delivery.

  • Is it safe to buy Synphase online?

    Yes – as long as you are buying from a website that is a legally operating and regulated pharmacy, it is perfectly safe to buy Synphase online.

    The Independent Pharmacy is an NHS Online Pharmacy based in Bristol and has all the necessary regulation to be able to safely provide convenient access to genuine prescription treatments through our Online Pharmacy and Online Doctor.

    All of our contraceptives are supplied by the same UK-based wholesalers used by the large high-street chains.

  • How do I buy Synphase online?

    It’s simple!

    Just select ‘Start Consultation’ next to the product above, or on the links below.

    You will need to fill in a simple health questionnaire so that our GPs and Pharmacists can ensure it is safe for us to supply your Synphase to you. It only takes a few minutes, and your treatment can be delivered to your door as soon as the next working day.

  • What does the price include?

    The price includes the medication you have selected, the private consultation with our Doctor and, if the purchase is over £40, it also includes free standard delivery. Under £40, standard delivery is £2.95 and all items are sent using a Royal Mail Tracked Service.

  • What are the advantages of buying Synphase online?

    There are many advantages to buying the Pill online, some include:

    • It's quick and easy- there is no need to spend time at the doctor or pharmacy.
    • Fast delivery- We offer same day dispatch before 4pm and fast delivery to your address of choice with Royal Mail.
    • Great prices- we are able to offer very competitive prices and we guarantee to beat any other Online Doctor service.
    • Wealth of information - we provide all the information you could need on Synphase and other contraceptives, in easy to digest formats, at a time that suits you.

We are a trusted pharmacy

We are regulated by a number of organisations in the UK including the MHRA, GPhC & CQC to ensure we offer the highest level of service to every one of our customers.

Why choose The Independent Pharmacy?

How does it work?

It's easy! Follow our simple process to get the treatment or advice you need in no time.

  • 1 Complete a simple health questionnaire
  • 2 A healthcare professional reviews your answers
  • 3 You receive the right treatment or advice
  • 4 Easily re-order in a few clicks

Can't find what you're looking for?

If you can't find what you are you looking for, please contact our support team on 0333 2200 519 for help and advice.

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