Amlodipine 5mg Tablets

Amlodipine Tablets (5mg & 10mg)

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Amlodipine is a calcium channel blocker, which is a group of medicines used to treat hypertension (high blood pressure) and angina. Calcium channel blockers work by relaxing the blood vessels, which leads to a decrease in pressure on the heart. Calcium channel blockers are generally used to treat mild to moderate cases of hypertension. Amlodipine is a daily tablet that is available in strengths of 5mg and 10mg. Amlodipine is the unbranded version of the drug Istin.

Muscle cells need calcium to contract. Amlodipine works by targeting muscle cells on the arterial walls throughout the body. This action blocks the cells access to calcium, which causes the muscles to relax. This results in a slight widening (dilation) of the arteries, which enables the heart to circulate blood with greater ease. This has the effect of lowering blood pressure. Amlodipine also acts on the arteries of the heart, causing the same mild dilation. This increases the oxygen supply to the heart, which helps to relieve the chest pain associated with angina. 

Hypertension, or high blood pressure, is very common. However, it does not usually present with any noticeable symptoms, which can leave many sufferers unaware of their condition. Under these circumstances, hypertension could potentially lead to serious complications with the heart, kidneys, brain, and other organs. If hypertension is ignored, the risk of suffering a heart attack, stroke, and/or kidney failure is significantly increased. Amlodipine, like other hypertension medication, is not able to cure high blood pressure. However, it will effectively help to manage the condition. If you have been prescribed Amlodipine, it is important you continue to take this medicine until your doctor advises that you stop.  

Hypertension treatment alone should not be relied on to treat your high blood pressure. Instead, treatments, such as Amlodipine, should be used to supplement a healthy lifestyle. There are a number of simple lifestyle choices that will greatly reduce the stress on your heart. This includes:

  • Reduce the amount of fat in your diet
  • Reduce the amount of salt in your diet
  • Exercise regularly
  • Quitting smoking
  • Cutting down on alcohol

You may be prescribed Amlodipine alongside other hypertension medicines, including Atenolol, Bendroflumethiazide or Losartan.

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Amlodipine is available in 5mg and 10mg tablets. Your recommended strength and dose of Amlodipine will vary depending on the nature of your condition, your medical history and whether you are taking it alone or alongside another blood pressure medicine. Always follow your doctor's directions exactly. Continue taking Amlodipine until your doctor advises that you stop, even if you feel healthy.

Generally, the initial dose is 5mg per day. Swallow the tablet whole with a sip of water. Amlodipine can be taken either with or without food.

If, for any reason, you forget to take a tablet, take it as soon as possible. However, if it is nearly time for your next tablet, skip the dose that you missed. Never double your dose to compensate for a dose that you have missed.

Alcohol does not directly interact with this medicine; however, you should avoid drinking heavily because the combination may lower your blood pressure excessively.

Not everyone will experience side effects when they take Amlodipine, however, if you do they can include:

Drowsiness, dizziness, headache, nausea, fatigue, stomach pain, heart palpitations, swelling of the ankle, blushing of the face or neck.

If you are concerned about these effects, or if the product affects you in any other way, stop using it and talk to your doctor or pharmacist as soon as possible.

Reading the following warnings carefully will help to ensure you are selecting an appropriate product.

Amlodipine is unsuitable if you:

  • Have low blood pressure
  • Are pregnant or breastfeeding
  • Have circulation problems or untreated heart failure
  • Suffer from aortic stenosis (a narrowing of the aortic valve)

Before taking Amlodipine, inform your GP if you:

  • Have liver disease
  • Have recently suffered a heart attack
  • Are elderly
  • Have heart failure

Tell your GP or pharmacist if you have taken or plan to take any of the following medicines:

  • Antifungal medicines (e.g. itraconazole, ketoconazole)
  • HIV medicines (e.g. ritonavir, nelfinavir)
  • Certain antibiotics: (e.g. erythromycin, rifampicin)
  • Certain heart medicines (e.g. verapamil, diltiazem)
  • St Johns Wort
  • Simvastatin (for high cholesterol)
  • Dantrolene

Avoid grapefruit juice, as it is known to interact with Amlodipine. A substance in the grapefruit increases the concentration of the drug within the bloodstream, which may make you more susceptible to side effects.

Please read all packaging and the Product Information Leaflet before taking any new medicine and inform your doctor of medicines you are taking or intend to take.

The active ingredient contained in Amlodipine tablets is Amlodipine.

Amlodipine tablets also contain the following inactive ingredients to make up the complete product:

Microcrystalline cellulose, anhydrous calcium hydrogen phosphate, sodium starch glyconate type A, magnesium stearate.

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Frequently Asked Questions

  • What is Amlodipine?

    Amlodipine is a prescription-only medicine that belongs to a group of drugs called calcium channel blockers.

  • What is Amlodipine used for?

    Amlodipine is used to treat hypertension (high blood pressure) and angina (chest pains). If taken regularly, amlodipine will help relieve and control chest pain. However, it will not stop chest pain once it has started.

  • How does Amlodipine work?

    Amlodipine works to lower blood pressure by relaxing the blood vessels. This reduces stress on the heart as it no longer needs to pump as hard. Relaxed blood vessels mean the heart can receive a greater supply of blood, which helps to alleviate the chest pain associated with angina.

  • What is Hypertension?

    Hypertension, or high blood pressure, is a common condition. If left untreated it can potentially lead to heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems.

  • Do I need to exercise if I’m taking medicine for high blood pressure?

    In addition to taking amlodipine, making healthy lifestyle changes will also help control your blood pressure. This will include, eating a low-salt/low-fat diet, maintaining a healthy weight and exercising for at least 30 minutes a day. If you are a smoker you should quit smoking. Also, you should only drink alcohol in moderation. Amlodipine tablets should serve to supplement a healthy lifestyle, not replace one.  

  • How do I Take Amlodipine?

    Amlodipine comes in tablet form. It is usually taken once a day. It is recommended to take the tablet at roughly the same time each day, following the printed directions on your medicine. Do not take any more or any less than is prescribed. Ask your doctor or pharmacist for advice if there is any part of your treatment you do not understand.

  • What dietary restrictions should I follow?

    If your doctor suggests a low-sodium (salt) diet, try to follow their directions carefully.

  • What happens if I forget a dose?

    You should take the missed dose as soon as you remember unless it is almost time for your next dose. In which case, skip the missed dose and continue with your next dose as normal. Never double-up a dose to compensate for a missed one.

  • Are there any special storage instructions?

    Amlodipine should be kept in the original container out of sight and reach of children. Store at room temperature away from excess heat or moisture.

  • How will I know if the tablets are working?

    You won't notice any difference immediately after taking amlodipine. It will usually take some time for your blood pressure to stabilise and start to reduce. To establish whether the medication is working, you will need to have your blood pressure measured and compared with previous readings.

  • Will I need to take Amlodipine forever?

    Unless specifically told otherwise by your doctor, you should continue to take amlodipine. Physical factors that may influence a reduction in your dose include; loss of weight, increased fitness, smoking cessation, dietary changes. In some cases, taking the tablets may no longer be necessary.

  • What will happen if I stop taking Amlodipine?

    Your blood pressure will rise, which will increase your chances of heart attack, stroke, and angina.

  • I have been prescribed another blood pressure tablet and the leaflet states not to take with other BP medication. Is this right?

    Amlodipine can be used alone or in combination with different blood pressure medicines. It is commonly prescribed alongside other medicines to treat hypertension.

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