We use website cookies to ensure that you receive the best experience. If you're happy and would like to carry on browsing click 'Accept', or find out more about our Cookie Policy. Accept

Paludrine/Avloclor Travel Pack

*The brand supplied may vary. Please contact us if you require a specific brand.

Paludrine/Avloclor Travel Pack

Sorry, this treatment is currently out of stock.

Our UK based support team can help, either email us at support@theindependentpharmacy.co.uk

Description for Paludrine/Avloclor Travel Pack

Avloclor tablets contain the active ingredient chloroquine and Pauldrine tablets contain proguanil. They work to kill any malaria parasites present in your blood following a mosquito bite. Paludrine/Avloclor are an effective combination to prevent malaria in certain areas where resistance is not present. The Paludrine/Avloclor travel pack has the benefit of being very cost effective and has fewer incidences of side effects than other antimalarials.

Product Information

  • Age: 18 years +

    Maximum per order: N/A

  • Pregnancy: N/A

    Breastfeeding: N/A


The Paludrine/Avloclor Travel Pack contains two active ingredients used for the prevention of malaria. The Paludrine tablet contains the drug proguanil hydrochloride, and the Avloclor tablet contains the drug chloroquine phosphate.

Paludrine and Avloclor work together to prevent malaria in certain areas where there is no resistance to antimalarial medicines. The Paludrine/Avloclor travel pack is a cost effective method of malaria prevention that has fewer incidences of side effects compared with other antimalarial medicines.

Malaria can potentially be a fatal disease. It is caused by a type of parasite called plasmodium. These parasites are carried by mosquitos and are injected into the bloodstream following a bite from an infected mosquito. Once inside the bloodstream, the parasite travels to the liver before reentering the bloodstream, where it begins to invade the red blood cells and reproduces. A malaria attack is triggered when the red blood cells start to burst, releasing a mass of plasmodium parasites into the bloodstream. The attacks will not begin until large enough numbers of blood cells have been infected with the plasmodium parasites.

Avloclor (chloroquine) and Paludrine (proguanil) actively work to kill any malaria parasites present in your blood following a bite from an infected mosquito. Chloroquine works by attacking the parasites after they have entered the red blood cells. From here it kills the malaria parasite and prevents them from multiplying further. Chloroquine’s mechanism of action is not completely understood, but it is thought to work by inhibiting the action of a chemical the parasite produces to protect themselves. Once inside the red blood cells, the malaria parasite digests the oxygen carrying pigment (haemoglobin) found in these cells. This has the effect of dividing haemoglobin into two parts; haem and globin. The haem part is toxic to the malaria parasite. To prevent itself from being harmed by haem, the parasite produces a chemical that converts the toxic haem into a non-harmful compound. Chloroquine inhibits the action of this chemical, causing the levels of haem to rise, which in turn kills the malaria parasites.

Proguanil works by preventing the malaria parasites from reproducing once they are inside the red blood cells. It achieves this by blocking the action of an enzyme called dihydrofolate reductase. This enzyme is found in the malaria parasites and is a key component in its reproductive process. Dihydrofolate reductase normally converts folic acid into folinic acid, which is an essential step for the parasite to produce new genetic material (DNA). Without new DNA the parasite is unable to reproduce.

Chloroquine and proguanil are taken together to prevent malaria. The chloroquine is only taken once weekly whereas the proguanil needs to be taken every day. However, the malaria parasite has developed a resistance to these medicines in certain areas of the world, which makes it very important to check with your pharmacist regarding the recommended treatment for your destination.

If the Paludrine and Avloclor Travel Pack is recommended, your treatment should be started one week prior to travel. They should be taken throughout your stay and continued for a further four weeks upon your return. This will ensure there is enough medicine in the blood to kill any remaining parasites released by the liver. In areas of possible chloroquine resistance, being combined with proguanil will help ensure you are adequately protected during your travels.

To find out whether Paludrine/Avloclor is the appropriate choice for your trip, check the Fit for Travel website for up to date travel health information.

Although Paludrine and Avloclor will help prevent contracting malaria, it is still important to prevent mosquito bites to further reduce your risk. For more information about malaria and effective bite prevention, visit our malaria page.

Additional steps you can take to minimise mosquito bites includes:

  • Wear light, long sleeved clothing and long trousers when outside after the sun has set
  • Use insect repellent, sprays or creams on the parts of your body not covered with clothes
  • Sleep under a mosquito net or in a properly screened room
  • Kill any mosquitos that have entered the rooms in spite of screening with sprays

Malaria can take up to one year to develop. If you experience symptoms including headaches, abdominal pains and night sweats any time during your travels or up to a year after returning, you must see a doctor straight away.

Pharmacist Tip

Chloroquine and Proguanil is suitable during pregnancy and breastfeeding. However, it should not be used by those who suffer with epilepsy or psoriasis. To help reduce potential side effects, these tablets should be taken with or just after food.

To prevent malaria, adults should take two Paludrine tablets once a day, at the same time each day. Two Avloclor tablets are taken once a week on the same day each week. Treatment should be commenced one week prior to travelling to the malaria area and continued throughout your stay. Upon returning form the malaria area, treatment should be continued for four weeks.

The correct dosage for children will depend on their age and body weight.

Paludrine and Avloclor should be taken with water, either with or just after food. If necessary, the tablets can be crushed and mixed with milk, jam or honey.

Do not take at the same time as indigestion remedies

If you forget to take your daily dose of Paludrine, take it as soon as you remember. However, if it is almost time for your next dose, skip the forgotten dose and take your next dose at the usual time. Never double-up a dose to compensate for a forgotten dose.

If you forget to take your weekly dose of Avloclor on the usual day, take it as soon as you remember. Then wait for seven days before taking your next dose. You should then continue to take Avloclor on this new day of the week.

There are currently no effective Non-Prescription Alternatives for Malaria treatment, however you can take more steps in avoiding being bitten while away by;

  • Using mosquito repellent containing DEET.
  • Using a mosquito net treated with insecticide while you are sleeping.
  • Using a sunscreen designed to help prevent mosquito bites
*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

Paludrine/Avloclor should be taken as follows for the greatest reduction in malaria risk:

  • You should take two Avloclor tablets every week on the same day each week.
  • You should take two Paludrine tablets every day at roughly the same time each day.
  • Paludrine/Avloclor needs to be taken one week before entering an area where malaria is present and continued until four weeks after leaving the malaria area.
  • You should take Paludrine/Avloclor with or after food.
  • Paludrine/Avloclor remains effective with a moderate alcohol intake.

If you do experience side effects from Avloclor they may include nausea, diarrhoea, headache, rashes, skin itch, blurred vision, hair loss, dizziness, mood change, sun sensitivity or seizures.  As such you should not take Avloclor if you or a close relative suffers with epilepsy. Avloclor can also worsen psoriasis; people who suffer with psoriasis should avoid taking Avloclor if possible. The side effects of Paludrine can include anorexia, nausea, diarrhoea, constipation, skin itch and mouth ulcers. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

Paludrine tablets:

  • Each Paludrine tablet contains 100 mg of proguanil hydrochloride (the active ingredient).
  • The other ingredients are calcium carbonate, gelatin, magnesium stearate and maize starch.

Avloclor tablets:

  • Each Avloclor tablet contains 250 mg of chloroquine phosphate (equivalent to 155 mg of chloroquine base).
  • The other ingredients are magnesium stearate and maize starch.

Paludrine can prolong bleeding time if taken with anticoagulants such as warfarin. If you take an anticoagulant you should speak to your GP before taking Paludrine/Avloclor. Please read the Patient Information Leaflet enclosed with your medicines for further information.

You should try to avoid taking Avloclor around the same time as indigestion or heartburn remedies containing high levels of calcium, iron or magnesium as this can reduce its effectiveness. 

Paludrine/Avloclor is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods. 

 It is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave.

The Paludrine/Avloclor Travel Pack should not be taken without checking with your GP if you take any of the following medicines:

  • Praziquantel (used to treat infections of the bowel and bladder caused by parasites).
  • Ciclosporin (mainly used by transplant patients but also used to treat rheumatoid arthritis and psoriasis).
  • Anti-convulsant medicines (used to prevent convulsions or fits).
  • Digoxin (used to treat heart problems).
  • Warfarin or other medicines used to prevent blood clots. Paludrine may increase the effect of these medicines.
  • Other medicines used to prevent malaria, such as mefloquine. There is a risk of convulsions or fits when these medicines are taken at the same time as Avloclor.
  • Cimetidine (used to treat stomach problems). This medicine affects how Avloclor is broken down by your body and may affect the amount of Avloclor in your blood.
  • Medicines like kaolin (used for diarrhoea) which are called ‘adsorbents’.
  • Antacids (aluminium, calcium and magnesium salts that are used to treat heartburn or indigestion).

You should not take Paludrine/Avloclor if you suffer with:

  • Epilepsy
  • Porphyria
  • Problems with your kidenys or liver
  • Myasthenia gravis
  • Psoriasis
  • Glucose-6-phosphate dehydrogenase deficiency

Delivery & Shipping Information


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2/3 day delivery - £2.95
  • Express Tracked Delivery - 1/2 day delivery - £4.45
  • DPD Next Day - 1 working day - £6.95
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail orders received before 4pm the same working day. Any orders received after 4pm or over the weekend will be dispatched the next working day. We aim to dispatch all DPD orders placed before 3pm on the same working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email and in your account.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.



DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 5.30pm the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 5.30pm to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 5.30pm to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Malaria Prevention?

Visit our advice area or contact our support team

Paludrine/Avloclor Travel Pack Reviews

Unsure about a treatment?
Take a free online assessment with our medical team for impartial help and advice on your condition.

We are a trusted online pharmacy

We are regulated by a number of organisations in the UK including the MHRA, GPhC & CQC to ensure we offer the highest level of service to every one of our customers.

Why choose The Independent Pharmacy?

How does it work?

It's easy! Follow our simple process to get the treatment or advice you need in no time.

  • 1 Complete a simple health questionnaire
  • 2 A healthcare professional reviews your answers
  • 3 You receive the right treatment or advice
  • 4 Easily re-order in a few clicks

Can't find what you're looking for?

If you can't find what you are you looking for, please contact our support team on 0333 2200 519 for help and advice.

Your basket

Your basket is empty

Start shopping

Did you know you can search from anywhere on the site? Simply press 's' on your keyboard and our quick search tool will appear.

Alternatively you can view a list of all of our treatments and treated conditions.

If you can't find what you are looking for, please contact our support team on 0333 2200 519.