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Elleste Duet tablets are a combined form of hormone replacement therapy (HRT), used to treat symptoms of the menopause. It has two active ingredients, which emulate the two female sex hormones: a natural version of the oestrogen (estradiol) and a synthetic version of progestogen (norethisterone). Cyclical combined treatments like Elleste Duet are appropriate for women who have started suffering from menopausal symptoms but still have somewhat of a menstrual cycle. If you have not had a hysterectomy, you will likely be prescribed a combined treatment.
All women go through the menopause. This usually occurs between the ages of 45 and 55. As you approach this age, your ovaries will produce less and less oestrogen. This has the effect of stopping the menstrual cycle, but the change in hormone levels can lead to several symptoms which may have a substantial impact on day-to-day life. Physical symptoms include hot flushes (a spontaneous heat that spreads throughout the body, leading to blushing, sweating and an unusually strong heartbeat), night sweats, osteoporosis and dryness of the eyes or vagina. The hormonal change can also cause distressing psychological effects such as irritability, insomnia and depression. Experiences with menopausal symptoms vary significantly depending on the individual. They can begin multiple years prior to the menopause itself, and remain for many years. Women will, on average, experience symptoms for about four years.
Hormone Replacement Therapy eases the symptoms of menopause by supplementing the levels of hormones which the body can produce naturally. Some medicines are oestrogen-only. However, in women who still have a uterus, an uncontrolled increase in oestrogen levels will cause the lining of the uterus (the endometrium) to grow excessively. This will substantially increase your risk of complications such as endometrial cancer. Elleste Duet is a cyclical treatment – the first 16 tablets in a cycle contain estradiol only, and the final 12 tablets contain a combination of estradiol and norethisterone. This causes a regular period and reduces your risk of cancer.
Three types of Elleste Duet are available. In the 1mg pack, the 16 white tablets contain 1mg estradiol; the 12 green tablets contain 1mg norethisterone as well as 1mg estradiol. In the 2mg pack, the 16 orange tablets contain 2mg estradiol; the 12 grey tablets contain 2mg estradiol and 1mg norethisterone. Elleste Duet Conti tablets contain 2mg estradiol and 1mg norethisterone in all the white tablets.
As your body adjusts to Elleste Duet, you may notice breakthrough bleeding or spotting. Talk to your GP if this continues after more than a few months of treatment HRT should only be necessary as a relatively short-term treatment as your body adjusts to the menopause. You should review your HRT with your GP at least once each year and have regular gynaecological checkups.
HRT will not prevent pregnancy in women who are otherwise fertile. Women under 50 are considered fertile until two years after their final menstrual cycle (for women over 50, this is reduced to one year). Do not use a hormonal contraceptive while undergoing HRT.
Why choose The Independent Pharmacy?
Elleste Duet HRT follows a 28-day cycle. If possible, begin taking the tablets on the first day of your period. The pill strip will indicate which tablet you are supposed to take next. Once you finish a pack, start a new one the following day.
Elleste Duet should be taken at a similar time each day, according to the directions on the pack. Swallow the tablet whole with a sip of water. This can be done with or without food.
If, for any reason, you forget to take a tablet, take it as soon as possible. However, if it is more than 12 hours late, skip the dose that you missed. Never double your dose to compensate for a dose that you have missed.
Not everyone will experience side effects when they take Elleste Duet, however if you do they can include:
Nausea, headache, breast tenderness, change in libido, anxiety, dizziness, insomnia, stomach cramps, breakthrough bleeding, diarrhoea, indigestion, acne, skin irritation, rash, back pain, discharge from the vagina, fluid retention, weight gain, womb spasms, infection.
If you are concerned about these effects, or if the product affects you in any other way, stop using it and talk to your doctor or pharmacist.
The active ingredients contained in Elleste Duet are:
Estradiol (as hemihydrate), norethisterone acetate (combined tablets only)
Elleste Duet tablets also contain the following inactive ingredients to make up the complete product:
Lactose monohydrate, maize starch, povidone, talc, magnesium stearate, macrogol 400 and hypromellose (E464).
1mg tablets – indigo carmine (E132), quinolone yellow (E104) and titanium dioxide (E171);
2mg tablets – sunset yellow (E110), titanium dioxide (E171), black iron oxide (E172).
Elleste Duet Conti tablets also contain the following inactive ingredients to make up the complete product:
Lactose monohydrate, maize starch, povidone, talc, magnesium stearate, macrogol 400, titanium dioxide (E171), black iron oxide (E172), hypromellose (E464).
Reading the following warnings carefully will help to ensure you are selecting an appropriate product.
Elleste Duet is unsuitable for you if you:
Inform your GP if you plan on taking Elleste Duet and have ever had any of the following health complications:
Tell your GP or pharmacist if you have taken or plan to take any of the following medicines:
As your body adjusts to Elleste Duet, you may notice breakthrough bleeding or spotting. Talk to your GP if this continues after more than a few months of treatment.
HRT may increase your risk of breast cancer. The extent of this risk will vary depending on the length of your HRT treatment and whether you are taking combined or oestrogen-only HRT. Check your breasts regularly for changes to the skin or nipple, or for any noticeable lump. For women who use HRT for more than five years, there may also be a slight increase in the risk of ovarian cancer.
Stop taking Elleste Duet Conti and seek medical attention immediately if you notice early signs of any of the following:
Discuss with your doctor whether your personal benefits of HRT outweigh the risks mentioned above.
Please read all packaging and the Product Information Leaflet before taking any new medicine and inform your doctor of medicines you are taking or intend to take.
We offer FREE standard tracked delivery on orders over £40.
The following delivery options are available:
All our orders are sent out using Royal Mail. We always aim to dispatch all orders received before
All orders can be fully tracked in your account.
We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods.
Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt.
Delivery is free for all NHS prescriptions.
Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering.
If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.
Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a
Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.
You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.
We are currently unable to ship orders outside of the UK.
We are unable to ship orders to
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You will need to fill in a simple health questionnaire so that our GPs and Pharmacists can ensure it is safe for us to supply your Elleste tablets to you. It only takes a few minutes, and your treatment can be delivered to your door as soon as the next working day.
The price includes the medication you have selected, the private consultation with our Doctor and, if the purchase is over £40, it also includes free standard delivery. Under £40, standard delivery is £2.95 and all items are sent using a Royal Mail Tracked Service.
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