The Wegovy Pill has been approved for use in the UK, offering eligible patients a needle-free GLP-1 weight loss treatment. The Independent Pharmacy expects to be among the early providers of this treatment following its UK launch.
Wegovy Pill (Semaglutide Tablet)
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Unavailable- A simple once-daily GLP-1 tablet designed to fit into your everyday life
- Average weight loss of around 17%, similar to the Wegovy pen¹
- No needles, pens or refrigeration needed
- No subscription lock-ins
- Fast, discreet delivery
- 100% UK-based pharmacy
- Free advice and support
- We're rated 4.9 out of 5
Based on over 30,000 reviews collected on Google and Reviews.io.
Wegovy Pill (Semaglutide Tablet): Overview
The Wegovy pill is an oral version of the well-known Wegovy injection, offering the same active ingredient in a once-daily tablet.
It contains semaglutide and is designed to support weight loss when used alongside a balanced diet and increased physical activity.
Semaglutide mimics a hormone called glucagon-like peptide-1 (GLP-1), which helps to:
- Slow the rate at which food leaves the stomach
- Increase feelings of fullness and reduce calorie intake
- Support better control of blood sugar levels
The Wegovy pill has been approved for use in the UK by the MHRA, providing eligible patients a needle-free GLP-1 weight loss treatment.
The Independent Pharmacy expects to be among the early providers of this treatment following its UK launch.
It could soon be prescribed for adults with a BMI of 30 or above, or 27 or above with a weight-related health condition.
Who Is the Wegovy Pill Suitable For?
Suitable for pregnancy?No
Suitable for breastfeeding?No
Maximums per order:
- 1
- 1
- 1
- 1
Consultation required?Yes
Wegovy Pill Summary
Wegovy Pill (Semaglutide Tablet): Information
Wegovy tablets are a prescription-only treatment, and are licensed for both weight loss and weight maintenance. If you’re an adult with obesity, or overweight with at least one weight-related medical condition, here’s what you need to know about the once-daily Wegovy tablet.
UK Availability
Wegovy tablets have now been approved for use in the UK by the Medicines and Healthcare products Regulatory Agency (MHRA). You can find out more in our Wegovy Pill guide.
What Is the Wegovy Pill?
The Wegovy pill is an oral version of Wegovy weight-loss injections. Both the tablets and the injections contain semaglutide, which can help you feel fuller for longer and reduce calorie intake.
Wegovy Pill vs Wegovy Injections: Comparison
Feature | Wegovy Pill | Wegovy Injections |
How it is taken | Taken orally as a tablet | Injected just under the skin |
Dosing frequency | Once daily | Once weekly |
When to take | First thing in the morning on an empty stomach, at least 30 minutes before food | Taken once a week on the same day each week |
How it is absorbed | Absorbed through the digestive system | Absorbed directly into the bloodstream |
Dose strengths | 1.5mg, 4mg, 9mg, 25mg | 0.25mg, 0.5mg, 1mg, 1.7mg, 2.4mg, 7.2mg |
Average weight loss | In the OASIS 4 trial, adults taking oral semaglutide experienced an average weight loss of 17% over 64 weeks¹ | In the STEP UP trial, adults treated with the semaglutide pen demonstrated an average weight loss of 21% over 72 weeks. |
Wegovy Pill vs Mounjaro Injections: Comparison
Feature | Wegovy Pill | Mounjaro Injection |
Active ingredient | Semaglutide | Tirzepatide |
How it works | Mimics the GLP-1 hormone | Mimics both GLP-1 and GIP hormones |
How it is taken | Oral tablet | Injection under the skin |
Dosing frequency | Once daily | Once weekly |
Average weight loss | In the OASIS 4 trial, adults taking oral semaglutide experienced an average weight loss of 17% over 64 weeks¹ | In the SURMOUNT-4 trial, adults taking tirzepatide experienced an average weight loss of 22.5% after 72 weeks² |
Learn more about the differences between Wegovy and Mounjaro in our comparison guide.
Wegovy Pill vs Ozempic: Comparison
Wegovy and Ozempic both contain semaglutide. Wegovy is licensed and dosed specifically for weight management, while Ozempic is licensed to treat type 2 diabetes. In some cases, healthcare professionals may prescribe Ozempic for weight loss.
How to Use Wegovy Tablets
- Take your Wegovy tablet first thing in the morning on an empty stomach.
- Swallow the tablet whole with up to 100ml of water. Taking it with more than this amount may reduce absorption.
- Wait at least 30 minutes before eating, drinking or taking other medicines.
Wegovy Pill Effectiveness
In the OASIS 4 clinical trial, oral semaglutide was shown to support weight loss in adults with overweight or obesity. Participants experienced an average weight reduction of 17% over the study period, with approximately one in three losing 20% or more of their starting body weight.¹
Wegovy Pill Ingredients
Active ingredient: Semaglutide
Other ingredients: salcaprozate sodium (SNAC) and magnesium stearate.
For the most up-to-date list of ingredients, please check the Patient Information Leaflet inside the box.
Wegovy Pill Side Effects
Like many medications, Wegovy may cause side effects. These can include:
- Nausea
- Vomiting
- Diarrhoea
- Dizziness
- Constipation
- Fatigue
- Heartburn
- Stomach (abdominal) pain
It’s important to follow the prescribed dosage and instructions from your clinical team. Be sure to inform your prescriber of any concerns or side effects you experience.
Wegovy Pill Warnings
Please read the following warnings carefully before use.
- Do not use Wegovy if you, or any of your family, have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Do not use Wegovy if you have had a serious allergic reaction to semaglutide or any of the ingredients in Wegovy tablets.
- Wegovy may cause thyroid tumours, including cancer. Tell your healthcare professional if you notice a lump or swelling in your neck, hoarseness, trouble swallowing or shortness of breath.
This treatment may not be suitable for all patients, including some older adults or those with complex health conditions.
For a full list of warnings and side effects, please see the Patient Information Leaflet.
Wegovy Pill (Semaglutide Oral Tablet) FAQs
Is there a Wegovy pill in the UK?
Not yet. The Wegovy pill has been approved in the UK by the Medicines and Healthcare products Regulatory Agency (MHRA), so it should be on sale soon at registered pharmacies, such as The Independent Pharmacy.
When is the Wegovy pill going to be available in the UK?
Wegovy tablets have now been approved and licensed in the UK for both weight loss and weight maintenance in adults who are overweight or obese.
Where can I buy the Wegovy pill in the UK?
The Wegovy pill will be available in the UK soon, having been approved by the Medicines and Healthcare products Regulatory Agency (MHRA).
Wegovy tablets are expected to become available through regulated pharmacies, such as The Independent Pharmacy. Here you will be able to:
- Complete a quick online medical assessment
- Be reviewed by an expert UK-based prescriber
- Receive discreet home delivery if prescribed
- Access support from our clinical team
How much will the new Wegovy pill cost?
Pricing details will be shared closer to launch. We expect the cost of a month’s supply of the tablet to be similar to that of the injectable pen, although this has not yet been confirmed.
Does the Wegovy pill cost more than the injection?
We do not expect the Wegovy pill to cost more than the injection. Current indications suggest the tablet and injection will be priced similarly, although final UK pricing will be confirmed soon.
How does the Wegovy pill work?
The Wegovy tablet activates the same receptors in the brain as the GLP-1 hormone. When combined with lifestyle changes, this may help reduce calorie intake.
Like the Wegovy injections, Wegovy tablets are always started at a low dose and increased gradually by your clinician. This allows your body to get used to the medication and keep side effects to a minimum.
The Wegovy tablet can only be taken:
- First thing in the morning on an empty stomach with no more than 100ml of water.
- 30 minutes before any other food or drink.
- Whole. Do not crush, chew, or split the tablet.
Important: Do not take the Wegovy pill with more than 100ml of water. Taking it with more than this may reduce the amount of the medication your body absorbs, making it less effective.
How effective is the Wegovy pill?
The Wegovy pill has undergone clinical trials to prove its efficacy. Results from the OASIS 4 trial showed that participants experienced an average weight reduction of 17% over the 64-week trial period. Approximately one in three people lost 20% or more of their starting body weight.
What is the difference between the Wegovy pill and the Wegovy injection?
The Wegovy tablet is taken once daily by mouth, while the Wegovy injection is administered once weekly under the skin. Because tablets are absorbed through the digestive system, different dosing strengths are used compared with the injection.
Is the Wegovy pill as effective as the injection?
Yes, clinical trials show that the Wegovy pill is as effective as the Wegovy injection.
Who is eligible for the Wegovy pill?
The Wegovy tablet could be prescribed for adults with:
- A body mass index (BMI) of 30 or above.
- A BMI of 27 or above with a weight-related health condition
You should not use Wegovy if you are pregnant, planning to get pregnant, or breastfeeding.
What Wegovy pill dosages and strengths are available?
The once-daily Wegovy pill is available in the following strengths:
- 1.5mg
- 4mg
- 9mg
- 25mg
How do I switch from Wegovy injections to the Wegovy pill?
While the Wegovy injections and pills both contain semaglutide, the dosages and strengths differ. This means any switch should be done under clinical supervision.
When Wegovy pills become available in the UK, and you’d like to understand more about how to make the switch, please get in touch with our trusted UK-based clinical team.
What if I miss a dose of the Wegovy pill?
If you miss a dose of the Wegovy pill, simply skip that day’s dose and take the next day’s as usual.
Is the Wegovy pill effective for weight loss in non-diabetics?
Yes, the Wegovy pill is effective for weight loss in non-diabetics.
In the OASIS 4 trial, published in November 2025, participants taking a daily 25mg dose of oral semaglutide experienced an average weight loss of more than 17%.
What happens if you take too much Wegovy?
If you think you have taken more Wegovy than prescribed, seek medical advice as soon as possible.
If you experience severe symptoms or feel seriously unwell, seek medical attention immediately.
What should I avoid while using Wegovy?
Wegovy works best alongside a healthy, balanced diet.
Avoid:
- High fat, greasy food
- Caffeine
- Excessive alcohol
- Spicy foods
- High sugar food and drink
You should also tell your prescriber about any medicines you are taking, particularly:
- Other weight loss treatments
- Other GLP-1 medicines
- Insulin or medicines used to treat diabetes
- Warfarin
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