Progynova Tablets

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Progynova Tablets
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Progynova for HRT

Progynova is an oestrogen-based Hormone Replacement Therapy (HRT) tablet that helps to relieve unpleasant symptoms of the menopause. It can be taken on its own for women who no longer have a womb or alongside an HRT containing progesterone.

Progynova can be bought online from The Independent Pharmacy by women who have previously received a prescription of Progynova from their GP. All you need to do is complete our online consultation today to get your HRT delivered directly to your door.

  • Suitable for age:18 Years +
  • Maximums per order:
  • Consultation required?Yes

Progynova Information

  • What is Progynova?

    Progynova is a form oestrogen-only HRT containing either 1mg or 2mg of estradiol, a form of the female hormone oestrogen with each pack including 3 blisters containing 28 tablets. Progynova is produced by the global pharmaceutical manufacturer Bayer. Progynova is taken every day without a break.

    Progynova tablets provide women who are experiencing the menopause, an increase in their oestrogen levels to relieve menopausal symptoms such as hot flushes, vaginal irritation and night sweats.

    Progynova tablet uses

    Progynova tablets are prescribed to women who are experiencing symptoms of the menopause that interfere with the quality of their daily life.

    Progynova tablets can help relieve the following symptoms of the menopause:

    • Hot flushes
    • Night sweats
    • Difficulty sleeping
    • Vaginal dryness and irritation
    • Reduced sex drive
    • Headaches
    • Low mood

    How does Progynova work?

    Progynova tablets contain a substance called estradiol that replicates how the female sex hormone oestrogen works in the body. As women start to go through the menopause their ovaries naturally stop producing as much oestrogen which causes some women to experience unpleasant symptoms.

    By taking an oral HRT that contains estradiol such as Progynova it reduces menopausal symptoms by mimicking the hormone oestrogen as it is absorbed into the blood through the digestive tract and is picked up by receptors.

    Progynova and alcohol

    Drinking alcohol while taking Progynova may increase the risk to some women of experiencing unwanted side effects such as headaches or feeling sick. If you choose to drink alcohol while using any form of HRT you should do so in moderation.

    If you are concerned about your alcohol consumption you should speak to a doctor or pharmacist for support.

    Alternatives to Progynova

    There are currently many varieties of HRT available on prescription including others containing oestrogen-only or combined HRT containing both synthetic oestrogen and progesterone.

    Progynova is an oestrogen-only HRT tablet that contains estradiol valerate. Equivalent HRT treatments include Elleste Solo tablets and Zumenon tablets.

    HRT is available in different formats such as tablets, patches, creams and vaginal inserts. Some women will find certain methods more suitable for them over others. For more information about what HRT you can buy from The Independent Pharmacy visit our Menopause page.

    If you are looking to start HRT or would like to change to a different treatment you should discuss your options with your doctor or specialist.


  • Progynova warnings

    Please make sure that you read the Patient Information Leaflet thoroughly paying particular attention to the warning and precautions, before starting treatment with Progynova.

    Using any form of HRT treatment, including Progynova tablets, increases the risk of you developing certain health conditions. If you have any questions or concerns you should discuss these with your GP or specialist.

    Purchasing Progynova tablets online as a repeat prescription from The Independent Pharmacy relies upon you continuing to attend an annual check-up with your GP.

    • Progynova tablets are not recommended for everyone. You should not use this product if you have ever had or are at risk of oestrogen-sensitive cancer, a blood clot, have a blood clotting disorder or have liver disease.
    • Discuss with your GP before taking Progynova tablets if you have or ever have had fibroids, endometriosis, have high blood pressure, diabetes, gallstones, SLE, epilepsy, asthma, kidney problems, suffer from migraines as HRT can make these conditions worse.
    • Speak to a doctor or pharmacist before taking Progynova if you are currently taking or have recently stopped taking any other prescribed or non-prescribed medicine including herbal remedies such as St John’s-Wort or drink grapefruit juice.

    Progynova tablets and cancer

    Progynova, like other oestrogen-only HRT, can put you at an increased risk of developing womb cancers. Progynova is therefore only suitable for women who do not have a uterus or are prescribed a progesterone HRT alongside it to reduce the risks.

    Progynova tablets may also increase your chances of developing breast cancer. You must, therefore, continue to regularly check your breasts for any variations including lumps and dimples. If you notice any irregularities you should get these checked by a doctor as soon as possible.

    Progynova and blood clots

    While using any form of HRT you are up to 3 times more likely to develop either a venous or arterial blood clot. These can be dangerous leading to heart attacks and strokes and can be life-threatening. If you think you are experiencing symptoms of a blood clot you must see a doctor straight away.

    Progynova & pregnancy

    Progynova is not a contraceptive and should only be taken by women experiencing the menopause. It should not be taken if you are pregnant or breastfeeding as the active ingredient can be passed to the baby. If you think you have become pregnant while using Progynova you should speak to a doctor for advice.

  • Progynova dosage

    Progynova tablets will be prescribed as either 1 mg or 2 mg tablets. These are to be taken orally only and you should take 1 tablet daily at around the same time. If you think the dose you have been prescribed is too high or too low you should discuss this with your doctor.

    • Swallow 1 tablet as prescribed every day for 28 days. When you finish a packet start a new 28 days packet the next day, do not have a break.
    • Start each new packet on the top row, taking the tablet that correlates with the correct day of the week and follow the directions of the arrows.
    • If you still have a womb or have a history of endometriosis you may also be prescribed a progesterone HRT alongside Progynova to take for the first 12-14 days of each month.

    Please make sure that you read the Patient Information Leaflet thoroughly before starting treatment with Progynova.

    Starting Progynova

    If you are switching from another HRT treatment:

    Finish your current pack of HRT and take your first Progynova tablet the day after you take your last HRT tablet.

    If you are taking HRT for the first time and still have regular periods:

    Take your first Progynova tablet on day 1 of your period.

    If you are taking HRT for the first time and have infrequent or no periods:

    Take your first Progynova tablet at any time if you are sure you are not pregnant.

  • Progynova ingredients

    Each Progynova tablet contains the active ingredient: estradiol valerate.

    Each Progynova tablet contains the inactive ingredients: lactose monohydrate, povidone 25,000, magnesium stearate (E572), sucrose, povidone 700,000, macrogol 6,000, calcium carbonate (E170), titanium dioxide (E171), glycerol 85% (E422), montan glycol wax, ferric oxide pigment (E172).

    Please make sure that you read the Patient Information Leaflet thoroughly before starting treatment with Progynova.

  • Progynova side effects

    Progynova tablets, like other HRT, can cause women to experience some unwanted side effects. Most of these side effects will improve within the first few months of use. If they do not improve within 3 months you should speak to a doctor or pharmacist.

    If you experience any severe side effects or allergic reaction while taking Progynova tablets you should seek medical advice from your nearest emergency department as soon as possible.

    The most common side effects are:

    • Breakthrough bleeding or spotting and painful periods
    • Breast pain, tenderness or enlargement or discharge
    • Changes in vaginal discharge and thrush
    • Fibroids in the womb
    • Indigestion, bloating or wind
    • Feeling or being sick
    • Gallbladder disease
    • Skin rashes or discolouration, itching, eczema
    • Acne or unusual hair loss or hair growth
    • Headache, migraine or dizziness
    • Mood changes - anxiety or depression
    • Fatigue

    Please make sure that you read the Patient Information Leaflet thoroughly before starting treatment with Progynova.

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