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Sandrena 0.5mg Gel Sachets

Sandrena Gel

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Order before 3pm for delivery from Fri. 18 Jun and Mon. 21 Jun.

Sandrena (Estradiol) Gel for HRT

Sandrena Gel is a light estrogen-based Hormone Replacement Therapy (HRT) gel that when applied to the skin helps to relieve unpleasant symptoms of the menopause. 

Sandrena Gel can be bought online from The Independent Pharmacy women experiencing the menopause that are currently prescribed Sandrena gel by their GP or menopause specialist. 

If you have previously received a prescription for Sandrena Gel from your GP, why not complete our online consultation today to get your HRT delivered directly to your door. 

Sandrena Gel Information

  • Age: 18 years +

    Maximum per order: 3

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

What is Sandrena Gel?

Sandrena Gel is an effective HRT that contains only estradiol, a bioidentical form of the female hormone oestrogen. Sandrena Gel gives women who are experiencing the menopause a boost of oestrogen to relieve menopausal symptoms such as hot flushes, vaginal irritation and night sweats.

This effective HRT gel is applied directly to the skin to start relieving symptoms within just a few weeks of use and is available on prescription as either containing 0.5mg or 1mg of estradiol. 

 

What is Sandrena Gel used for?

Sandrena Gel is prescribed to women who experience symptoms of the menopause that significantly affect their experience of daily life. 

Symptoms of the menopause Sandrena Gel can help to relieve:

  • Hot flushes
  • Night sweats
  • Difficulty sleeping
  • Vaginal dryness and irritation
  • Reduced sex drive
  • Headaches
  • Low mood

 

How does Sandrena Gel work?

During the menopause or after the removal of the whole or parts of the female reproductive system the body’s oestrogen levels drop causing unpleasant symptoms. 

Sandrena Gel is an alcohol-based product that contains a synthetic oestrogen called estradiol. When applied to the skin the alcohol in the gel evaporates quickly allowing the estradiol to be absorbed through the skin into the blood circulation increasing the oestrogen levels and reducing symptoms. 

 

Sandrena Gel and other HRTs

Sandrena Gel can be used by women with and without a womb, however, the method of HRT can be different in the two groups.

In women who have an intact uterus (they have not had a hysterectomy), Sandrena Gel should be combined with a progesterone-only HRT (such as Utrogestan) so that both oestrogen and progesterone are replaced and the risks of using HRT are lowered.

In women who have do not have a uterus (they have had a full hysterectomy), Sandrena Gel will be used as their only HRT treatment as progesterone will not be required.

Women who have had a partial hysterectomy will be advised by the doctor on their regime of HRT depending on whether they have any endometrial lining.

 

Sources

*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

Sandrena Gel dosage

  • Sandrena Gel should only be used by women who are experiencing symptoms of the menopause and have been prescribed by their GP following an initial health assessment. 
  • You will either be prescribed 0.5mg, 1mg or 1.5mg per daily dose and should only use as directed by your doctor.
  • Sandrena Gel should only be applied to the skin avoiding the breasts, face and any areas of irritated or broken skin. Recommended areas for application are the thighs and the lower body and you should rotate the application sites to either side of your body daily.
  • If you have never used HRT before or are changing from a period-free HRT you can start using Sandrena straight away. If you have never been prescribed HRT before, you should speak to your GP or a menopause specialist to have your treatment initiated after a face-to-face consultation.
  • If you still have an intact womb (you haven't had a hysterectomy) you should speak to your doctor before using Sandrena Gel as they will likely prescribe another HRT containing a form of the hormone progesterone.

 

How to apply Sandrena Gel

  • Clean and dry the area in which you would like to apply the gel.
  • Once a day, open the correct number of sachets that make up your daily dose. 
  • Spread the gel over the skin, covering an area 1- 2 times the area of your own hand. 
  • Leave the gel to dry for a few minutes before covering with any clothing and do not wash the area for at least an hour. 
  • Wash your hands thoroughly after each application. 

Please read the Patient Information Leaflet carefully before using Sandrena Gel.

Sandrena Gel side effects

Sandrena Gel, like other HRT, can cause some people to experience some unwanted side effects. Most side effects will improve within the first few months of use. If they do not get better within this time you should speak to a doctor or pharmacist. 

If you experience any severe side effects or allergic reaction while using Sandrena Gel you should seek medical advice from your nearest emergency department as soon as possible. 

The most common side effects experienced when using Sandrena Gel are:

  • Itching of the skin or rash 
  • Increased sweating 
  • Swelling in the feet and lower legs 
  • Tender or painful breasts 
  • Increase or decrease in your weight
  • Headaches or migraines 
  • Dizziness
  • Abdominal pains, feeling or being sick 
  • Irregular menstrual bleeding
  • Changes in mood 
  • Changes to sex drive

Please read the Patient Information Leaflet carefully before using Sandrena Gel.

Sandrena Gel ingredients

Each Sandrena Gel sachet contains the active ingredient: either 0.5mg or 1.0mg of estradiol. 

Each Sandrena Gel sachet contains the inactive ingredient: Carbopol 974P, trolamine, propylene glycol, alcohol and purified water. 

Please read the Patient Information Leaflet carefully before using Sandrena Gel.

Sandrena warnings

Please read the Patient Information Leaflet carefully before using Sandrena Gel.

Using any form of HRT treatment, including Sandrena Gel, can increase your risks of developing certain health conditions. If you have any questions or concerns you should discuss these with your GP or specialist. 

Your suitability to continue purchasing Sandrena Gel on repeat prescription from The Independent Pharmacy relies upon you maintaining annual check-up with your GP, which should include a breast screen, blood pressure, blood tests and a cervical smear test.

  • Sandrena Gel may not be suitable for everyone. You should not use this product if you have ever had or are at risk of estrogen-sensitive cancer, a blood clot, have a blood clotting disorder or have liver disease.
  • Discuss with your GP before using Sandrena Gel if you have fibroids, endometriosis, have high blood pressure, diabetes, gallstones, SLE, epilepsy, asthma, kidney problems, suffer from migraines as HRT can make these conditions worse.
  • Speak to a doctor or pharmacist before using Sandrena Gel if you are currently taking or have recently stopped taking any other prescribed or non-prescribed medicine including herbal remedies such as St John’s-Wort.

 

Sandrena Gel and cancer

Sandrena Gel, like other estrogen-only HRT, can put you at an increased risk of developing cancers of the womb. Sandrena is therefore only suitable for women who do not have a uterus or are prescribed a progesterone HRT alongside it to reduce the risks. 

All HRT may also increase your chances of developing breast cancer and therefore you must continue to regularly check your breasts for any changes including lumps and dimples. If you notice any irregularities you should get these checked by a doctor as soon as possible. 

 

Sandrena Gel and blood clots 

While using any form of HRT you are up to 3 times more likely to develop either a venous or arterial blood clot. These can be dangerous leading to heart attacks and strokes and can be life-threatening. If you think you are experiencing symptoms of a blood clot you must see a doctor straight away. 

 

Sandrena & Pregnancy

Sandrena Gel is only suitable for women experiencing the menopause and should not be taken as a contraceptive or when pregnant. If you think you have become pregnant while taking Sandrena Gel you should speak to a doctor for advice. 

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.

 

UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2 - 3 day delivery - £2.95
  • Express Tracked Delivery - 1 - 2 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail & DPD orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email, in your online account and from any notifications from your courier.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.

 

Royal Mail

Features:

  • Fully tracked delivery
  • SMS & email notifications
  • Four-hour delivery window
  • Change delivery date directly with Royal Mail
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local Post Office or Royal Mail Customer Service Point.

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.

 

DPD

Features:

  • Fully tracked delivery
  • SMS & email notifications
  • One-hour delivery window
  • Change delivery date directly with DPD
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local collection point.

DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.

 

Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

 

BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.

 

Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50
ZE1

 

We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
GY10
HS2
PA60 - 75, 78
ZE2, 3

 

We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
KW17
PH30, 41 - 44

 

Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.

 

International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Menopause (HRT)?

Visit our advice area or contact our support team

Sandrena Gel Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Authored By:

A photo of  Scott McDougall

Scott McDougall

MPharm

Published on: 24-12-2020

Last modified on: 24-12-2020


Scott is one of the two founders of The Independent Pharmacy. He is a registered pharmacist and the registered manager of our service with the CQC.

Reviewed By:

A photo of  Andy Boysan

Andy Boysan

BPharm

Reviewed on: 24-12-2020

Next review date: 24-12-2022


Andy is a co-founder, the superintendent pharmacist and director at The Independent Pharmacy.


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