Detrusitol XL 4mg Capsules

Detrusitol XL 4mg Capsules (28 capsules)

Order before 4pm for delivery from Fri. 24 Mar.

Product Information

  • Age: 18

    Maximum per order: 1

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Overactive bladder syndrome is unpleasant and embarrassing. If you have overactive bladder syndrome you may find that you are unable to control urination and that you need to go to the toilet frequently or rush to the toilet with no advance warning. Coughing, sneezing or weight bearing exercises may also cause urine to leak from the bladder unexpectedly. There are many reasons why people suffer from urinary incontinence which include getting older, certain types of surgery, pregnancy and being overweight.

Detrusitol is used for the treatment of the symptoms of urinary incontinence. Detrusitol is known as an antimuscarinic medication, it works by relaxing the muscles in the bladder thereby offering relief from the symptoms of urinary incontinence. Detrusitol capsules are prescribed to patients who are experiencing the symptoms of overactive bladder syndrome or urge incontinence; they are also available in a prolonged release form called Detrusitol XL.

Detrusitol is a slow release treatment which means that the medication is absorbed gradually into the bloodstream throughout the course of the day. The active ingredient in Detrusitol which is called Tolterodine Tartrate increases the amount of urine the bladder can retain by relaxing the detrusor muscle-the smooth muscle of the bladder wall - so the bladder will stop randomly contracting and be effective in holding in its contents. This will greatly reduce your need to frequently pass urine and increase the storage volume of the bladder. Detrusitol can also act on the brain to delay the desire to urinate.

The recommended dose of Detrusitol XL is a 4mg tablet which should be taken once a day. Try to take the capsule at the same time each day.

You can take the capsule with or without food and it should be swallowed whole with water. The capsule should not be opened, crushed or chewed.

If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose. In this case, ignore the missed dose and take your next capsule as usual when it is due.

Do not take two capsules to make up for a missed dose.

Some people may experience dizziness when taking Detrusitol. If you encounter any feelings of dizziness, light headedness or any other side effects when taking Detrusitol, you should stop the medication immediately and discuss these symptoms with your doctor.

Do not take Detrusitol XL if you:

  • are allergic (hypersensitive) to tolterodine or any of the other ingredients in Detrusitol XL
  • are unable to pass urine from the bladder (urinary retention)
  • have an uncontrolled narrow-angle glaucoma (high pressure in the eyes with loss of eyesight that is not being adequately treated)
  • suffer from myasthenia gravis (excessive weakness of the muscles)
  • suffer from severe ulcerative colitis (ulceration and inflammation of the colon)
  • suffer from a toxic megacolon (acute dilatation of the colon).

Take special care with DETRUSITOL XL:

  • If you have difficulties in passing urine and/or a poor stream of urine
  • If you have a disease that affects the passage and/or digestion of food
  • If you suffer from kidney problems (renal insufficiency)
  • If you have a liver condition
  • If you suffer from neuronal disorders that affect your blood pressure, bowel or sexual function (any neuropathy of the autonomic nervous system)
  • If you have a hiatal hernia (herniation of an abdominal organ)
  • If you ever experience decreased bowel movements or suffer from severe constipation (decreased gastrointestinal motility)
  • If you have a heart condition such as an abnormal heart tracing (ECG);a slow heart rate;(bradycardia); relevant pre-existing cardiac diseases such as ;cardiomyopathy (weak heart muscle), myocardial ischaemia (reduced blood flow to the heart), arrhythmia (irregular heartbeat) and heart failure.
  • If you have abnormally low levels of potassium (hypokalaemia), calcium (hypocalcaemia) or magnesium.

Talk to your doctor or pharmacist before starting your treatment with Detrusitol XL if you think any of these might apply to you

Taking other medicines

Tolterodine, the active substance of Detrusitol XL, may interact with other medicinal products.

It is not recommended to use tolterodine in combination with:

  • some antibiotics (containing e.g. erythromycin, clarithromycin)
  • medicinal products used for the treatment of fungal infections (containing e.g. ketoconazole, itraconazole)
    medicinal products used for the treatment of HIV.

Detrusitol XL should be used with caution when taken in combination with:

  • medicines that affect the passage of food (containing e.g. metoclopramide and cisapride)
  • medicines for the treatment of irregular heartbeat (containing e.g. amiodarone, sotalol, quinidine, procainamide)
  • other medicines with a similar mode of action to Detrusitol XL (antimuscarinic properties) or medicines with an opposite mode of action to Detrusitol XL (cholinergic properties). Ask your doctor if you are unsure.

Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Taking Detrusitol XL with food and drink

Detrusitol XL can be taken before, after or during a meal.

Pregnancy and breast-feeding

Pregnancy - You should not use Detrusitol XL when you are pregnant. Tell your doctor immediately if you are pregnant, think you are pregnant or are planning to become pregnant.

Breast-feeding - It is not known if tolterodine, the active substance of Detrusitol XL, is excreted in the mother's breast milk. Breast-feeding is not recommended during administration of Detrusitol XL.

Ask your doctor or pharmacist for advice before taking any medicine.

Driving and using machines

Detrusitol XL may make you feel dizzy, tired or affect your sight; your ability to drive or operate machinery may be affected.

Important information about some of the ingredients of Detrusitol XL

This medicine contains sucrose (a type of sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine. Patients with rare hereditary problems of fructose intolerance, glucose- galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

The active substance in Detrusitol XL 4 mg prolonged-release capsules is 4 mg of tolterodine tartrate, equivalent to 2.74 mg of tolterodine.

The other ingredients are:

Capsule contents: Sugar spheres (containing sucrose and maize starch), hypromellose and Surelease E-7-19010 (containing ethylcellulose, medium chain triglycerides and oleic acid).

Capsule shell: Gelatine and colourants.


Blue 4 mg prolonged-release capsule: Indigo carmine (E132) and titanium dioxide (E171).

Printing ink: Shellac glaze, titanium dioxide (E171), propylene glycol and simeticone.

Need to know more about Urinary Incontinence?

Visit our advice area or chat online to our support team

Frequently Asked Questions

  • What are the symptoms of urinary incontinence?

    Urinary incontinence is characterised by an inability to control urination and a desire to rush to the toilet frequently, often without any warning.

  • What is urge incontinence?

    Urge incontinence is caused by uncontrollable spasms in the detrusor muscle which is located in the bladder. These involuntary contractions cause the bladder to empty, usually without warning.

  • What causes urinary incontinence and urge incontinence?

    There are lots of causes for urinary incontinence and urge incontinence which include getting older, certain types of surgery, pregnancy and being overweight.

  • How do Detrusitol tablets work?

    Detrusitol tablets are an antimuscarinic medication that works by inhibiting specific receptors located on the cells on the surface of the detrusor muscle, the muscarinic receptors, consequently causing this muscle to relax; this increases the amount of urine the bladder can retain. Detrusitol is a slow release treatment which means that the medication is absorbed into the bloodstream gradually throughout the course of the day.

  • Can I buy Detrusitol from my local pharmacy?

    Detrusitol and Detrusitol XL are only available on prescription in the UK.  This is because a doctor will need to check if it is safe for you before you use it.

  • I would be too embarrassed to visit my GP with symptoms of urinary incontinence?

    Detrusitol is a prescription only medicine and you can buy this at The Independent Pharmacy thus avoiding the embarrassment of visiting your doctor. In order to purchase Detrusitol, you will first need to complete a short and simple online consultation which will help our doctors ensure that this medication is safe for you to use. If your consultation is approved, we can send your prescription straight to you using our free and discreet delivery service.

  • What are the benefits of Detrusitol?

    The main benefit of Detrusitol is its effectiveness in treating the frustrating symptoms of incontinence which can be uncomfortable, very embarrassing and ultimately lifestyle limiting. Clinical studies demonstrate that the active ingredient in Detrusitol, Tolterodine Tartrate, will reduce the frequency of passing urine in the majority of cases.

  • Who cannot take Detrusitol?

    Detrusitol is suitable for both men and women suffering from symptoms of an overactive bladder and urinary incontinence. However some diseases and conditions will mean that Detrusitol is not a suitable medication.  Always consult your healthcare professional before taking Detrusitol and read the Product Information leaflet thoroughly to make sure that it is safe for you to take Detrusitol.

  • Can I drink alcohol if I am taking Detrusitol?

    Yes it is quite safe to drink alcohol whilst taking Detrusitol tablets.  However excessive consumption of alcohol can exacerbate the symptoms of urinary urgency so alcohol should only be consumed in moderation.

  • Can I take Detrusitol if I am pregnant?

    Detrusitol is not suitable for women who are pregnant or breastfeeding.

  • Will I still be to drive?

    Yes it is safe for you to drive when taking Detrusitol but the tablets can cause dizziness so if you experience this, you should stop taking the medication at once and consult your healthcare professional.

  • Will Detruistol interact with the medication I take already?

    Please read the following warnings carefully to ensure that Detrusitol is safe for you to use. Detrusitol is not suitable for people who have any of the following conditions or diseases:-

    • Gastro intestinal disease, kidney problems or liver problems.
    • Constipation.
    • Heart conditions
    • Neuronal disorders affecting blood pressure, bowel or sexual function.
    • Low levels of potassium or magnesium in the bloodstream.
    • For women who are pregnant or breastfeeding.
    • For those currently on a course of antibiotics.
    • An allergy to Tolterodine or any other ingredient found in this medication.

    Always discuss with your Doctor any other medicines you may be taking before being prescribed Detrusitol; this includes other prescription medicines and any other medication which may have been obtained without prescription.

    Store Detrusitol in a safe place at a temperature below 30°C.

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