We use website cookies to ensure that you receive the best experience. If you're happy and would like to carry on browsing click 'Accept', or find out more about our Cookie Policy. Accept

Aciclovir 400mg Tablets

*The brand supplied may vary. Please contact us if you require a specific brand.

Aciclovir 400mg Tablets

Order before 4pm for delivery from Fri. 18 Oct.

Product Information

  • Age: 18

    Maximum per order: 6

  • Pregnancy: N/A

    Breastfeeding: N/A

Aciclovir/Acyclovir (Zovirax) is an antiviral tablet, which is used to prevent or treat infections from the herpes simplex virus (HSV). It cannot completely cure herpes but will stop the growth of the virus and suppress the symptoms. Aciclovir can also be used as a means to prevent recurrent outbreaks. It is one of the most popular treatments in the UK for genital herpes.


Treating genital herpes 

Genital herpes is a common infection that causes painful blisters on the genitals and nearby areas. It is caused by the herpes simplex virus (HSV). The herpes virus can impact any mucous membrane on the body; this includes the moist lining of the mouth, where HSV manifests as cold sores. Genital herpes is most often transmitted through sexual contact, and so is commonly classified as a sexually transmitted infection (STI). Like many STIs, HSV is highly contagious and can be spread by any direct contact with the affected areas.

Two types of HSV exist, type 1 (HSV-1) and type 2 (HSV-2). Genital herpes is caused by one of two strains of HSV, type 1 (HSV-1) or type 2 (HSV-2). Aciclovir will help to treat both strains of the virus.


Treatment and prevention

If you begin to take Aciclovir as soon as symptoms appear, the outbreak will often disappear within one to two days. Recurrent outbreaks are usually preceded by a tingling or itching sensation. If you take Aciclovir as soon as you notice these signs, blisters may not occur at all. Aciclovir targets the enzyme that is necessary for the HSV to replicate and grow. By stopping further production of this enzyme, the virus cannot reproduce and create more blisters. This allows the immune system to fight the remaining virus and end the outbreak.

After taking Aciclovir, you should wait until the affected area has healed before resuming sexual activity. Once the virus has fully gone into remission, it will no longer be contagious. Aciclovir is the generic version of the brand Zovirax.


Why choose The Independent Pharmacy?

Fast – order before 4pm and receive your treatment as quickly as the next day
Free online consultation service with one of our registered GMC doctors
Discreet packaging & confidential service – we don't include any branding or pharmacy logo on our packaging, meaning you can get your treatment delivered anywhere
UK based and GMC UK registered doctors
Only proven prescription medication available
Approved by the National Pharmacy Association and Care Quality Commission.


Non-prescription alternatives to Aciclovir

  • Cleaning the area with water or salt water to promote healing
  • Avoid wearing tight clothing
  • Use pain relief such as paracetamol
  • Try to avoid your known outbreak triggers such as excess alcohol.
  • Use Vaseline on the blisters to promote healing and relieve pain.

Aciclovir 400mg Tablets Patient Information Leaflet: https://www.medicines.org.uk/emc/product/2352/pil

*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

Begin taking Aciclovir as soon as you notice symptoms of the herpes virus, which include visible blisters and a burning sensation. Each tablet is 400mg – take one tablet three a day for five days, or for as long as is prescribed. If you are taking Aciclovir to prevent future recurrences of herpes, you will likely be prescribed two tablets per day for a period of three to six months.

Swallow each tablet whole with a sip of water. Aciclovir can be taken with or without food.

HSV infections are contagious and can be spread even if you are taking Aciclovir. So, be sure to frequently wash your hands and do not allow the infected area to make contact with others.

Aciclovir can put stress on the kidneys, so ensure that you remain thoroughly hydrated while taking the tablets.

If you have forgotten to take a tablet, have it as soon as possible. Never double a dose to make up for one you have missed.

Not everyone will experience side effects when they take Aciclovir, however, if you do they may include:

Dizziness, headache, nausea, diarrhoea, allergic reaction, rash, stomach pain, fatigue, fever, heightened sensitivity to light

If you are concerned about these effects, or if the product affects you in any other way, stop using it and talk to your doctor or pharmacist.

The active ingredient contained in Aciclovir tablets is:

Aciclovir PhEur

Aciclovir tablets also contain the following inactive ingredients to make up the complete product:

Colloidal anhydrous silica, magnesium stearate, polyvidone, sodium starch glycollate, E172, E460.

Reading the following warnings carefully will help to ensure you are selecting an appropriate product.

Before you take Aciclovir, inform your doctor of any kidney problems or nervous system abnormalities. Remaining fully hydrated while taking. Aciclovir will minimise the effect on the kidneys.

Inform your doctor of any medicines you are taking or intend to take, especially:

  • Cimetidine (for peptic ulcers)
  • Probenecid (for gout)
  • Mycophenolate mofetil
  • Ciclosporin (an immunosuppressant)
  • Theophylline (for asthma)
  • Zidovudine (for HIV infections)

Please read all packaging and the Product Information Leaflet before taking any new medicine.

Delivery & Shipping Information


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2/3 day delivery - £2.95
  • Express Tracked Delivery - 1/2 day delivery - £4.45
  • DPD Next Day - 1 working day - £6.95
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail orders received before 4pm the same working day. Any orders received after 4pm or over the weekend will be dispatched the next working day. We aim to dispatch all DPD orders placed before 3pm on the same working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email and in your account.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.



DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 5.30pm the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 5.30pm to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 5.30pm to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Genital Herpes?

Visit our advice area or contact our support team

Aciclovir 400mg Tablets Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Frequently Asked Questions

  • Is Aciclovir the same as Acyclovir?

    Yes, the two are one and the same thing – an antiviral medication used to treat HSV infections, chickenpox and shingles. The Independent Pharmacy is able to prescribe Aciclovir online to treat genital herpes.

  • Are Aciclovir tablets antibiotics?

    Aciclovir tablets are not antibiotics – they are an antiviral medication. Antibiotics are used to fight bacterial (not viral) infections.

  • Do Aciclovir tablets help cold sores?

    Yes, you can take Aciclovir tablets to treat cold sores. In some cases, they can be more effective than cream. However, they are usually prescribed for more severe cold sore outbreaks. The Independent Pharmacy are able to provide Aciclovir 400mg tablets to treat genital herpes and Aciclovir 200mg tablets to treat cold sores.

  • Is Aciclovir a steroid?

    No. Aciclovir is a topical antiviral drug, but it is not a steroid. 

  • Is Aciclovir safe long term?

    Yes, it is generally thought that Aciclovir is safe to take long term over several months, which is helpful for those who experience recurrent genital herpes to keep it under control. The side effects are few and rarely serious.

  • Does Aciclovir have side effects?

    Aciclovir has occasional side effects, which most commonly include nausea, vomiting, diarrhoea, and sometimes tiredness (if you are on a higher dose). 

  • Will Aciclovir help thrush?

    Aciclovir is used to treat viral infections. This makes it an unsuitable treatment for thrush, which is a fungal infection.

  • Does Aciclovir make you tired?

    One of the less common side effects of Aciclovir is that it can make you feel slightly tired, particularly if you’re taking a higher dose to combat shingles. You shouldn't get this side effect if you are treating genital herpes.

  • Are Aciclovir tablets safe in pregnancy?

    It’s thought that most herpes medication is relatively safe to take while pregnant, at least in the early stages of pregnancy. Ensure that you speak to your doctor/consultant for a specific recommendation if you need to treat herpes if you are pregnant. To our knowledge, Aciclovir tablets are not associated with birth defects. 

  • Do Aciclovir tablets affect the contraceptive pill?

    Some medicines can interact with the contraceptive pill and prevent it from working as it should. However, there are no known interactions between Aciclovir and the contraceptive pill, so it is safe to take both at the same time. However, if you experience any side effects such as vomiting or diarrhoea, be aware that both can impact the pill’s effectiveness.

  • Does Aciclovir cause weight gain?

    There is no evidence to suggest that taking Aciclovir has any direct link to weight gain.

  • Does Aciclovir cause hair loss?

    There is some research to suggest that Aciclovir can contribute to hair loss in some patients, however, it is one of the less common side effects.

  • Are Aciclovir tablets available over the counter?

    No – Aciclovir is a prescription-only treatment that must be prescribed by a doctor or pharmacist. You can purchase Aciclovir through The Independent Pharmacy following an online consultation.

  • Do Aciclovir tablets go out of date?

    When you buy Aciclovir, you’ll find an expiration date on the packaging. While taking out-of-date medication is unlikely to cause harm, it does reduce the likelihood of the treatment being effective, so we always recommend replacing your medicine if it is out-of-date.

  • Should Aciclovir be taken with food?

    Aciclovir can be taken with or without food – it’s up to you – but taking it with food may help to reduce the likelihood of getting an upset stomach. Each dose of Aciclovir should be taken with a large glass of water.

  • How quickly should Aciclovir work?

    Ideally, you should start taking Aciclovir as soon as possible after symptoms have started to present themselves. It can also be taken as a preventative measure for long-term sufferers. If it’s your first time taking Aciclovir, the first course will likely be around 10 days. The results are not instantaneous, so keep using the treatment consistently as instructed to start seeing an improvement.

Authored By:

A photo of  William Obeng

William Obeng

MPharm IP

Published on: 02-02-2017

Last modified on: 02-02-2019

Reviewed By:

A photo of  Andy Boysan

Andy Boysan


Reviewed on: 02-02-2019

Next review date: 02-02-2021

We are a trusted online pharmacy

We are regulated by a number of organisations in the UK including the MHRA, GPhC & CQC to ensure we offer the highest level of service to every one of our customers.

Why choose The Independent Pharmacy?

How does it work?

It's easy! Follow our simple process to get the treatment or advice you need in no time.

  • 1 Complete a simple health questionnaire
  • 2 A healthcare professional reviews your answers
  • 3 You receive the right treatment or advice
  • 4 Easily re-order in a few clicks

Can't find what you're looking for?

If you can't find what you are you looking for, please contact our support team on 0333 2200 519 for help and advice.

Your basket

Your basket is empty

Start shopping

Did you know you can search from anywhere on the site? Simply press 's' on your keyboard and our quick search tool will appear.

Alternatively you can view a list of all of our treatments and treated conditions.

If you can't find what you are looking for, please contact our support team on 0333 2200 519.