Avloclor 250mg Tablets

Avloclor 250mg Tablets

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Warning - we can only provide up to 300 days of medication in advance
Please note the below order is only calculated for 300 days from the first date selected. If you require any assistance with your order please contact our support team.

Order before 4pm for delivery from Tue. 01 Aug.

*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.
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Please note, we calculate the required treatment quantity for you, including any dose to cover the full course before and after the time period specified so you will always have a complete course of medication. If you would like to find out more before purchasing please contact our UK support team via Email, Phone or Online Chat

Description for Avloclor 250mg Tablets

Avloclor (Chlororquine) 250mg tablets are a convenient and cost-effective treatment for malaria prevention in some areas that pose a malaria risk. Avloclor tablets can be bought online without a prescription, quickly and easily from The Independent Pharmacy.

Product Information

  • Age: 18 years +

    Maximum per order: N/A

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Avloclor (Chloroquine) 250mg Tablets are available to buy from The Independent Pharmacy Online Doctor service, following a free consultation, to help prevent malaria. To find out more about malaria and see all the available treatments, see our Online Doctor Malaria page.

Avloclor Tablets are mainly used for the prevention and the treatment of Malaria. Each tablet contains 250mg of the active ingredient Chloroquine Phosphate. Avloclor is classified as a prescription-only-medicine (POM) and is manufactured in the UK by Alliance Pharmaceuticals. Avloclor tablets are white and round. One side is scored down the middle with the letter ‘A’ marked on either side of the score-line. The other side of the tablet is plain with no markings. Avloclor are taken as a single dose of 2 tablets once weekly, started one week before travelling and continued for 4 weeks after returning.

Malaria is a serious disease that can potentially be fatal. It is caused by various types of parasites known as plasmodium. Mosquitos infected with plasmodium can pass them on to humans through bites. If bitten by an infected mosquito the plasmodium will be transferred into the human bloodstream. Once there, it will begin to reproduce and multiply, resulting in the disease malaria.

Chloroquine Phosphate belongs to a group of medicines called antimalarials. Basically, Chloroquine works by killing the plasmodium once it has entered the red blood cells. It does this by inhibiting the action of a chemical the plasmodium produces to protect themselves. Once inside the red blood cells the plasmodium starts to digest the oxygen carrying pigment haemoglobin, separating it into two parts; haem and globin. However, haem is toxic to the plasmodium. To protect themselves, the plasmodium produces a chemical that renders the haem non-toxic to them. Chloroquine blocks the action of this haem detoxifying chemical, causing a rise in toxicity that will kill the malaria parasites.

Avloclor can be taken on its own or in combination with another antimalarial medicine called Proguanil. Knowing which antimalarial treatment is right for you will depend on your destination. Different regions, countries and continents can be affected by different forms of the malaria causing parasite. Different parasites can react differently to different treatments. In some cases the plasmodium has developed a resistance to one form of treatment. For example, plasmodium falciparum is known to be resistant to Chloroquine. For areas where this plasmodium is prevalent, Chloroquine will not be an effective means of prevention. An alternate, such as Malarone, will be more suitable.

Please read the Patient Information Leaflet for side effects and additional information.

Pharmacist Tip: Chloroquine is suitable during pregnancy and breastfeeding, however it should not be taken if you suffer with epilepsy or psoriasis. The tablets should be taken with or after food to help reduce side effects.

There are currently no effective Non-Prescription Alternatives for Malaria treatment, however you can take more steps in avoiding being bitten while away by;

  • Using mosquito repellent containing DEET.
  • Using a mosquito net treated with insecticide while you are sleeping.
  • Using a sunscreen designed to help prevent mosquito bites
  • You should take two tablets every week on the same day each week.
  • Avloclor needs to be taken one week before entering an area where malaria is present and continued until four weeks after leaving the malaria area.
  • You should take Avloclor with or after food.
  • Avloclor remains effective with a moderate alcohol intake.

If you do experience side effects from Avloclor they may include nausea, diarrhoea, headache, rashes, skin itch, blurred vision, hair loss, dizziness, mood change, sun sensitivity or seizures.  As such you should not take Avloclor if you or a close relative suffers with epilepsy. Avloclor can also worsen psoriasis; people who suffer with psoriasis should avoid taking Avloclor if possible. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0117 971 1603. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.

 

The active substance in Avloclor Tablets is chloroquine phosphate. Each tablet contains 250 mg of chloroquine phosphate (equivalent to 155 mg of chloroquine base).

The other ingredients are magnesium stearate and maize starch.

Avloclor is not suitable to be prescribed online if:

  • You are allergic (hypersensitive) to chloroquine phosphate or any of the other ingredients of Avloclor (see Section 6: Further information).
  • You are taking a medicine called amiodarone (used to control the heart rate). Avloclor may increase the risk of uneven heart beats (cardiac arrhythmias) when it is taken at the same time as amiodarone. Check with your doctor or pharmacist if you are not sure.
  • You have ever had epilepsy, convulsions or fits.
  • You have ever had problems with your liver or kidneys.
  • You have ever been told that you have a rare disease of the blood pigment called ‘porphyria’ or anyone in your family has it. This is because Avloclor may cause severe symptoms of porphyria, particularly if you drink alcohol.
  • You have a scaly condition of the skin called psoriasis.
  • You have a muscle problem called ‘myasthenia gravis’. Avloclor can increase the symptoms of this condition. It can also reduce the effect of medicines used to treat this condition (neostigmine and pyridostigmine).
  • You have a blood problem called ‘glucose-6-phosphate dehydrogenase deficiency’. Avloclor may damage blood cells in people with this blood condition.

Avloclor may not be suitable to be prescribed online if you are taking any of the following medicines. This is because Avloclor may affect the amount of these medicines in your blood. Please ensure you let us know in your online consultation if you are taking any of the following medicines:

  • Praziquantel (used to treat infections of the bowel and bladder caused by parasites).
  • Ciclosporin (mainly used by transplant patients but also used to treat rheumatoid arthritis and psoriasis).
  • Anti-convulsant medicines (used to prevent convulsions or fits).
  • Digoxin (used to treat heart problems).
  • Other medicines used to prevent malaria, such as mefloquine. There is a risk of convulsions or fits when these medicines are taken at the same time as Avloclor.
  • Cimetidine (used to treat stomach problems). This medicine affects how Avloclor is broken down by your body and may affect the amount of Avloclor in your blood.
  • Medicines like kaolin (used for diarrhoea) which are called ‘adsorbents’.
  • Antacid medicines (aluminium, calcium and magnesium salts that are used to treat heartburn or indigestion).

You should try to avoid taking Avloclor around the same time as indigestion or heartburn remedies containing high levels of calcium, iron or magnesium as this can reduce its effectiveness. 

Avloclor is not 100% effective at preventing malaria, however it is still very effective if taken properly and combined with bite avoidance methods.

It is also important to get the correct vaccinations for your trip before you travel. These should be administered around 6 weeks before you leave.  

UK ORDERS

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2/3 day delivery - £2.95
  • Express Tracked Delivery - 1/2 day delivery - £4.45
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

All our orders are sent out using Royal Mail. We always aim to dispatch all orders received before 4pm the same working day. Any orders received after 4pm or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders can be fully tracked in your account.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.

 

REMOTE AREAS

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 5.30pm the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50
ZE1

 

We deliver within two working days by 5.30pm to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
GY10
HS2
PA60 - 75, 78
ZE2, 3

 

We deliver within three working days by 5.30pm to the following postcode areas:
KW16 - non-Town
KW17
PH30, 41 - 44

 

Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.

 

INTERNATIONAL ORDERS

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Malaria Prevention?

Visit our advice area or chat online to our support team

Unsure about a treatment?
Take a free online assessment with our medical team for impartial help and advice on your condition.

Frequently Asked Questions

  • What is Avloclor used for?

    Avloclor is a pharmacy medicine (P) used to prevent malaria. This treatment can be purchased from a pharmacy without a prescription for this purpose.

    Avloclor is often taken in combination with another antimalarial called Proguanil. However, In certain areas of the world, the malaria parasite is becoming resistant to these medicines. For this reason, it is important to check with your pharmacist about which medicine is appropriate for your destination. Alternatively, you can check on the government website fitfortravel.com

  • What causes Malaria?

    Malaria is caused by a single-celled parasite known as plasmodium. Some mosquitos are infected with this parasite. If bitten by an infected mosquito, the plasmodium will likely be injected into the victim's bloodstream. Once there, the parasite will travel through the bloodstream to the liver, where they will begin to multiply.

    After their numbers have increased, the plasmodium is released back into the bloodstream, where they will start to invade the red blood cells, further multiplying in the process. An actual attack of malaria occurs when the invaded red blood cells burst, spewing a further mass of parasites into the bloodstream. The attacks only begin after a sufficient number of blood cells have been infected with plasmodium.

  • How does Avloclor work?

    Avloclor works by attacking the plasmodium after they have penetrated the red blood cells. It kills the parasites and prevents them from multiplying further.

  • How do I take Avloclor?

    Avloclor should be taken with a glass of water, either with or just after food. If necessary, the tablets can be crushed and mixed with milk, honey, or jam.

    Two tablets should be taken once a week, on the same day each week. The course should be started one week prior to travelling to the malarious area. You should regularly take the tablets every week throughout your stay and continued for a further four weeks upon your return. This course ensures there will be enough medicine in the blood to kill any remaining parasites released from the liver. If you forget to take you weekly dose, you should take two tablets as soon as you remember. You will then need to wait 7 days before taking your next dose.

    Avoid taking any indigestion remedies 2-3 hours before and after taking Avloclor

  • What should I know before I start taking Avloclor?

    For some, Avloclor can cause visual disturbances in the initial stages of use. If you find yourself affected in this way, take extra care when driving or operating heavy machinery.

    Avloclor may result in low blood sugars (hypoglycaemia), which may cause; cold sweats, pale skin, lethargy, headache, difficulty concentrating, confusion, nausea, and palpitation.

    Whilst taking antimalarial treatments, such as Avloclor, it is strongly advised to take additional precautions to avoid being bitten by mosquitos. This should include the use of nets and repellents. These precautions are particularly important if you are suffering from vomiting and diarrhoea, as these inflictions can affect the absorption of Avloclor from the gut.

    If you fall ill within one year of your return (especially if within 3 months), you should consult with your doctor straight away, letting he/she know that you have visited a country where malaria is endemic.   

  • Who should not take Avloclor?

    Avloclor isn’t suitable for everyone. People with a history of epilepsy should avoid taking this medicine.

    Avloclor should not be taken if you are allergic to any of its ingredients. If you suffer an allergic reaction, stop taking this medicine and inform your doctor or pharmacist without delay.

    If you are taking Avloclor for any reason other than preventing malaria, it is advised to check with your doctor before breastfeeding.

  • Does Avloclor interact with other medicines?

    Prior to starting a course of Avloclor, It is very important to inform your doctor or pharmacist about any medicines you are already taking. This will include prescription medicines, over-the-counter medicines, and any herbal or alternative medicines or supplements. Similarly, check with your doctor or pharmacist before starting any new medicines whilst taking Avloclor. 

    Common medicines that should be avoided whilst taking Avloclor include:

    • Antacids – these medicines can reduce the absorption of Avloclor from the gut, meaning the full dose is not absorbed into the body. Antacids should be avoided for 2-3 hours prior to and after taking Avloclor.
    • Cimetidine – may inhibit the breakdown of Avloclor by the liver, which can lead to increased levels of Avloclor in the blood. This will increase the risk of experiencing unwanted side effects.
    • Ciclosporin/digoxin – Avloclor can increase the blood level of these medicines, which will result in an increased risk of suffering their side effects.
    • Insulin/diabetes medicines – if taken with insulin or other diabetes medicines, Avloclor can increase the risk of hypoglycaemia (low blood sugars). If you have diabetes, a dose adjustment may be required whilst taking Avloclor. Please ask your doctor for advice.
    • Mefloquine/bupropion – there may be an increased risk of convulsions if Avloclor is taken with these medicines.
    • Neostigmine/pyridostigmine – Avloclor can reduce the effectiveness of these medicines used to treat myaesthenia gravis.
    • Oral thyroid vaccine – this vaccine’s effectiveness can be reduced by Avloclor. If immunisation is required, ensure the vaccine course is completed at least three days before you start taking Avloclor.

    This list is not exhaustive, always inform your doctor or pharmacist about any medicine you take before starting to take Avloclor.

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  • 1 Complete a simple health questionnaire
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  • 3 You receive the right treatment or advice
  • 4 Easily re-order in a few clicks

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