Azithromycin 500mg Tablets

Azithromycin 500mg Tablets

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Order before 4pm for delivery from Tue. 25 Jul.

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  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Azithromycin is a first-line treatment for traveller’s diarrhoea caused by common bacterial infections in most countries. It is an antibiotic that kills diarrhoea-causing bacteria and reduces the symptoms and duration of traveller’s diarrhoea, especially when taken with loperamide. The dose of Azithromycin is one tablet daily for three days. Begin taking Azithromycin as soon as you develop diarrhoea, not before. It cannot be used as a preventative measure.
You can also take the anti-sickness tablet, Avomine, to minimize fluid loss and discomfort.
Azithromycin is the preferred antibiotic for treating travellers' diarrhoea in South Asia (India, Pakistan) or SE Asia (Thailand, Laos, etc.). In other parts of the world, the antibiotic ciprofloxacin is preferred.
Traveller's Diarrhoea is a common condition effecting 20-50% of international travellers. It usually occurs during the first two weeks of travel to a foreign country, especially in the developing world where it can effect up to 60% of travellers.
Symptoms of Traveller's Diarrhoea include passing three or more unformed stools within 24 hours, often accompanied by nausea, stomach pain, bloating, vomiting and/or fever.
Traveller's Diarrhoea can be contracted when the body is exposed to unfamiliar bacteria. Bacterial infections normally account for around 85% of cases. For the local population, these bacteria are often harmless but for a foreign traveller they may result in infection. Viruses and parasites may also account for a minority of traveller’s diarrhoea.
The organisms that cause traveller's diarrhoea include bacteria such as E. coli and Salmonella, parasites such as Giardia and viruses like norovirus. These organisms can be contracted through contaminated food and beverages as well as contact with dirty hands and plates.
Avoiding contaminated foods is the most effective way to prevent Traveller's Diarrhoea. Basic precautions include:
Drink only safe water and beverages that have been boiled, bottled or distilled. Avoid tap water and hot drinks which have not been boiled.
Avoid ice cubes as they may be made with contaminated tap water.
Avoid ice-cream and other frozen desserts as many developing countries experience frequent power cuts which means these products can defrost and refreeze at unsafe temperatures.
Avoid raw fruit and vegetables that you have not peeled.
Avoid salads as they may have been washed with contaminated water.
Wash your hands before eating.
Standby treatment is recommended for the following travellers:
Travellers who often experience diarrhoea while travelling abroad
Travellers with bowel conditions such as IBS.
Travellers to destinations far from medical help.
Travellers who have conditions which may be aggravated by severe dehydration/diarrhoea.

How to take Azithromycin tablets (antibiotics)

  • Take one tablet a day for 3 days.
  • Continue the course until it is complete unless a doctor directs otherwise.
  • Start taking Azithromycin as soon symptoms of traveller’s diarrhoea occur. These include diarrhoea, sickness, nausea and stomach cramps.

How to take Loperamide capsules (anti-diarrhoeals)

  • Take two capsules at the onset of diarrhoea, followed by a further capsule after each loose bowel movement.
  • You should never take more than 8 capsules in 24 hours.

How to take Dioralyte sachets (rehydration sachets)

  • Dissolve the contents of one sachet in roughly 200mL of fresh drinking water. Where fresh drinking water is unavailable, you should use water that has been freshly boiled and cooled.
  • The solution should be made up immediately before use and consumed within one hour. If it is possible to refrigerate the mixture it can be stored for up to 24 hours.

Side effects can include:

Mild allergic reactions (serious reactions are rare). If you develop any of the following symptoms, contact your doctor immediately.

  • Sudden difficulty in speaking, breathing and swallowing
  • Swollen lips, face, tonue and neck
  • Extreme dizziness or fainting
  • Severe or itchy skin rash, especially if it includes blistering and the eyes, mouth or genital organs become sore.

Contact your doctor as soon as possible if you develop any of the following symptoms:

  • Diarrhoea that lasts a long time, is serious or has blood, accompanied by stomach pain or fever. This can signal a rare but serious bowel inflammation.
  • Yellowing of the whites of the eyes or skin as this can signal liver problems.
  • Severe pain in the abdomen and back which can indicate inflammation of the pancreas.
  • Reduced or increased urine output, or traces of blood in the urine
  • Skin rash caused by photosensitivity
  • Unusual bruises or bleeding
  • Irregular heart beat.

Other common side effects:

  • Diarrhoea
  • Abdominal pain
  • Nausea
  • Flatulence
  • Lack of appetite
  • Feeling dizzy
  • Headache
  • Tingly sensation or numbness
  • Changes in your sense of taste
  • Vision impairment
  • Deafness
  • Vomiting, stomach pain or cramps, digestion problems
  • Skin rashes and itching
  • Joint pain
  • Fatigue
  • Change in the concentration of bicarbonate in the blood and the quantity of the white blood cells.

If you are concerned about these effects, or if the product affects you in a different way, stop using Azithromycin and talk to your doctor or pharmacist.

Azithromycin 500mg tablets contain:

Active ingredient: azithromycin 500mg.

Inactive ingredients: croscarmellose sodium (E468), magnesium stearate (E572), silicium dioxide (E551), microcrystalline cellulose (E460), poloxamer, povidone (E1201), talc waterfree lactose.

Coating: hypromellose (E464), hydroxypropyl cellulose, macrogol, titanium dioxide (E171).

Do not take Azithromycin tablets if:

  • You have liver, kidney, or heart problems.
  • You have low levels of potassium or magnesium.
  • You develop symptoms of another infection.
  • You take any derivatives of ergot such as ergotamine (for migraines).
  • You have muscle weakness, myasthenia gravis.
  • You have neurological or psychiatric problems.

Consult your doctor or pharmacist if you are taking any of the following medications:

  • Antacids - Azithromycin should be taken at least 1 hour before or 2 hours after the antacid.
  • Ergotamine (for migraine treatment). It should not be taken with Azithromycin as the combination may cause serious side effects such as numbness or tingling in the limbs, headaches, muscle cramps, convulsions, chest or abdominal pain.
  • Cholesterol-lowering medications (statins).
  • Warfarin or similar medicines (blood thinners). Azithromycin can further thin the blood.
  • Cisapride (for stomach problems). This medication should not be taken with Azithromycin as severe heart problems may result.
  • Terfenadine  (for hay fever). When taken with Azithromycin, severe heart problems may develop.
  • Zidovudine or Nelfinavir  (for HIV treatment). Taking nelfinavir with Azithromycin may make you susceptible to more of the side effects listed in this leaflet.
  • Rifabutin (for tuberculosis treatment).
  • Quinidine (for treatment of heart rhythm problems).
  • Cyclosporin (for preventing organ-rejection). Your doctor will regularly check your blood levels of cyclosporin and may change your dose.

Please read all packaging and the Product Information Leaflet before taking any new medications. Inform your doctor about any medications you take or intend to take.


We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2/3 day delivery - £2.95
  • Express Tracked Delivery - 1/2 day delivery - £4.45
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

All our orders are sent out using Royal Mail. We always aim to dispatch all orders received before 4pm the same working day. Any orders received after 4pm or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders can be fully tracked in your account.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.



Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 5.30pm the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 5.30pm to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 5.30pm to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.



We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Traveller's Diarrhoea?

Visit our advice area or chat online to our support team

Frequently Asked Questions

  • What does Azithromycin do?

    Azithromycin works by destroying the bacteria responsible for causing diarrhoea. It achieves this by preventing the bacteria from producing the proteins they need to survive.

  • How effective is Azithromycin?

    Azithromycin is a highly effective treatment for traveller’s diarrhoea. However, its overall effectiveness is rated at 97%, as it has proved ineffective against giardia and amoebic dysentery. If Azithromycin doesn’t successfully clear up you diarrhoea, you should seek further advice from a doctor.

  • How can I tell if the treatment is working?

    Taking Azithromycin will reduce the overall duration of your diarrhoea. Without treatment, symptoms usually persist for 3-4 days. Using Azithromycin will cut this time down to 1-2 days. You will know whether Azithromycin is working by whether your symptoms have cleared up within this time. If the diarrhoea persists, consult with a doctor.

  • When do I need to start treatment?

    Treatment should be commenced as soon as you notice any symptoms of diarrhoea. These symptoms include; frequent loose stools, nausea, and stomach cramps. The sooner treatment is started, the quicker your recovery will be.

  • Will I need to continue the course until the Diarrhoea has completely cleared up?

    Yes. This will help prevent resistant strains of bacteria from developing.

  • Can I drink alcohol whilst taking Azithromycin?

    No. Alcohol can potentially neutralise the positive effects of Azithromycin. This will mean your diarrhoea won’t be cured effectively.

  • Where in the world is Azithromycin a good option?

    Azithromycin is the best method for treating bacterially caused diarrhoea. Azithromycin is particularly effective in South East Asia. This is because, in that region, most cases of diarrhoea are caused by bacteria.

  • Do I need a prescription to obtain Azithromycin?

    Yes. Azithromycin is a prescription-only-medicine (POM). A private prescription can be issued online by visiting The Online Doctor at The Independent Pharmacy. After your consultation is reviewed by one of our doctors, your treatment can be promptly dispatched.

  • Is Azithromycin known as anything else?

    Brand names of Azithromycin include; Zithromax and Zmax.

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