Differin 0.1% cream & gel are available to buy from The Independent Pharmacy, following a free consultation, to help to treat acne.
Differin cream & gel contains the active ingredient adapalene and is used in the treatment of acne. Differin is a retinoid-like compound that is manufactured by Galderma UK Limited. The active ingredient in Differin, Adapalene, is a form of vitamin A. It works to reduce the growth of keratin surface skin cells that can block pores.
Sebum is produced by glands just under the surface of the skin called sebaceous glands. Sebum is a natural, oily substance needed to keep the skin smooth and supple. However, sufferers of acne often produce too much sebum, which can mix with the dead keratin skin cells and cause the pores to become blocked. Blocked pores can then lead to the formation of spots, blackheads (comedones) and whiteheads. Applying Differin 0.1% Cream to the affected areas will help reduce the amount of keratin skin cells and unblock the pores and sebaceous glands, allowing the sebum to escape. This will result in a reduction of inflammation, whiteheads, comedones and spots.
Differin 0.1% cream/gel is also beneficial as it increases the natural turnover of the skin cells. This aids the natural exfoliation of the skin’s outer layers. This action will help keep pores unblocked, thus reducing the formation of spots and blackheads.
Differin 0.1% cream/gel is for external use only and is designed to treat mild to moderate acne symptoms. Currently, Differin is the only licensed medicine in the UK to contain the active ingredient Adapalene.
Pharmacist tip: Differin cream/gel should be applied once daily, in the evening. It should be applied to the affected areas after they have been washed and patted dry. You can use cosmetics and moisturisers whilst using Differin, however you should let it absorb into your skin fully before applying them.
- Differin cream/gel should be applied to the affected areas once daily in the evening, after washing with a mild cleanser.
- Apply a small amount to cover the affected areas using clean fingertips and rub in lightly.
- At the start of treatment with Differin, if it is used correctly it will produce effects similar to that of mild sunburn including mild itching, redness and warmth. This is normal and should subside.
To get the best effects from Differin cream/gel it is important that it is for up to THREE months continuously depending on response. Improvement should be seen after a few weeks.
You may use cosmetics and moisturisers whilst you are using Differin cream however you should wait for it to be fully absorbed into the skin before applying anything else.
Differin has drying effect on the skin so it is important to try to ensure that any toiletries containing alcohol or other skin-drying ingredients are not used.
Like all topical applications there is the potential that you may be allergic to Differin. We recommend you do a spot test before commencing treatment.
If you do experience side effects from Differin cream/gel, they can include a burning, stinging or tingling feeling, dry skin, itching, redness, or a rash. Differin can also cause your skin to be more sensitive to sunlight meaning you may burn in the sun more easily than normal. You should take action to reduce this risk such as wearing protective clothing or using sunscreen. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.
If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately. Please log in to your online account and message one of our healthcare professionals or alternatively call us on 0333 2200519. In a medical emergency you should contact the emergency services or go straight to your local Accident & Emergency.
Do not use this medicine on areas where you have cuts or scrapes or if you have a skin condition called eczema.
Avoid contact with the eyes, mouth or nostrils, and avoid other very sensitive areas of the body. If accidental contact does occur, immediately wash with warm water.
Avoid exposure to strong sunlight and artifcial UV light. If you experience sensitivity or irritation when applying this medicine, stop using it and tell your doctor. You may be asked to use the gel less often, or to stop using it for a short time. Talk to your doctor or pharmacist if you are not sure.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
- Other acne products (containing benzoyl peroxide, erythromycin or clindamycin) may be used with Differin but they must be applied in the morning and Differin at night.
- Cosmetics may be used but they must not cause blackheads or dry the skin.
Pregnancy and breast-feeding
- Differin should not be used during pregnancy. If you fall pregnant while using Differin, the treatment must be discontinued and you should inform your doctor as soon as possible for a further follow-up.
Differin contains the active ingredient adapalene 0.1%.
Differin Cream also contains: carbomer 934P, Macrogol-20 methyl glucose sesquistearate, glycerol (E422), natural squalene, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), disodium edetate, methyl glucose sesquistearate, phenoxyethanol, cyclomethicone, sodium hydroxide & purified water.
Differin Gel also contains: carbomer 940, propylene glycol (E1520), poloxamer 182, disodium edetate, methylparahydroxybenzoate (E218), phenoxyethanol, sodium hydroxide and puri ed water.