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Chlorphenamine 4mg Tablets

*The brand supplied may vary. Please contact us if you require a specific brand.

Chlorphenamine Tablets & Solution

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Order before 3pm for delivery from Tue. 29 Sep and Wed. 30 Sep.

Product Information

  • Age: N/A

    Maximum per order: N/A

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Chlorphenamine tablets are a type of antihistamine medication that contains an active ingredient known as chlorphenamine maleate (previously spelt chlorpheniramine in the UK). Chlorphenamine is known as a sedating antihistamine, which works by preventing the actions of histamine within your body. Chlorphenamine tablets can be used to treat the symptoms associated with allergic conditions such as:

  • Hay fever
  • Nettle rash (urticarial)
  • Food allergies
  • Allergic reactions to insect bites
  • Allergic reactions to some medications


Chlorphenamine tablets are also effective at treating more severe allergic reactions, known as angioneurotic oedemas, which can create a wide range of symptoms such as swelling of the eyes, throat, and tongue. Chlorphenamine can also be used to treat the itchy symptoms associated with chickenpox.

Histamine is a chemical that is produced within the body and acts as a natural defence mechanism to foreign invaders. Most of the cells in your body contain histamine. When foreign substances are detected in the body, such as allergens like pollen, the cells become stimulated and release their histamine. Once it has been released it binds to your body’s H1 receptors, causing a reaction which creates the symptoms associated with allergies that you are familiar with. This increases blood flow to the problem area, causing the body to release other chemicals which add to the symptomatic response.

In hay fever, for example, this process can cause an inflammation of the nose and eyes, congested airways, as well as itchy, watery eyes, a runny nose, and bouts of sneezing. Histamine is responsible for these symptoms, as well as other symptoms associated with allergic reactions to foods, medicines, and insects.

Chlorphenamine treats your symptoms by blocking your body’s histamine H1 receptors. Your cells will still release their histamine; however Chlorphenamine will prevent them from binding to your H1 receptors. This has a knock-on effect of stopping the release of other allergy related chemicals and preventing the blood flow to the area from increasing. Because it causes drowsiness once it has entered the brain, Chlorphenamine is called a sedating antihistamine.

This combined action is the reason that Chlorphenamine is an effective treatment for the itchiness associated with chickenpox. This can be particularly beneficial in preventing night time itching - especially in children that become particularly bad at coping with the condition during the night.

If you plan to have any tests in order to diagnose your allergies then you should stop taking Chlorphenamine tablets at least two days before the tests. Because Chlorphenamine treats the symptoms of allergies it can interfere with the efficacy of the tests.

Chlorphenamine should not be used if you have taken any monoamine oxidase inhibitos (MAOIs) in the last 14 days. MAOIs are a kind of antidepressant, some examples are:

  • Phenelzine
  • Tranylcypromine
  • Isocarboxazid


Chlorphenamine can cause drowsiness. If you experience drowsiness while taking Chlorphenamine then avoid driving or operating machinery. Alcohol should also be avoided.

The risk of experiencing certain side effects including dry mouth, blurred vision, and constipation, can be increased if using Chlorphenamine at the same time as antimuscarinic medicines such as:

  • Antimuscarinic medicines for Parkinson’s symptoms such as procyclidine, orphenadrine, and trihexiphenidyl
  • Antimuscarinic medicines for urinary incontinence such as oxybutynin, flavoxate, tolterodine, propiverine, and trospium
  • Some antipsychotics such as chlorpromazine and clozapine
  • Antispasmodics such as hyoscine and atropine
  • Tricyclic antidepressants such as amitriptyline, imipramine


Piriton is another medication for allergic reactions which contains the same active ingredients as Chlorphenamine tablets.


Anyone over the age of twelve should take one Chlorphenamine tablet every four to six hours, taking a maximum of six in one 24 hour period. The elderly should avoid taking more than three tablets per day as they will increase their risk of developing potential side effects.

Children between the ages of six and twelve can take half a Chlorphenamine tablet every four to six hours, taking no more than three tablets in a 24 hour time period.

It is not recommended for children under the age of six to take Chlorphenamine tablets. Instead, Chlorphenamine syrup can be used. Never exceed the recommended daily dose.

If, after using this treatment, you still experience the symptoms associated with allergies, you should seek advice from your doctor or pharmacist.


*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 3 - 5 day delivery - £2.95
  • Express Tracked Delivery - 1 - 3 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email and in your account.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.



DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Hay Fever?

Visit our advice area or contact our support team

Chlorphenamine Tablets & Solution Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Authored By:

A photo of Dr Donald Grant

Dr Donald Grant

MB ChB DRCOG MRCGP Dip.orth.med

Published on: 25-01-2017

Last modified on: 25-01-2019

Dr Don Grant is a GP with over 30 years experience and is the Clinical Advisor at The Independent Pharmacy

Reviewed By:

A photo of  Scott McDougall

Scott McDougall


Reviewed on: 25-01-2019

Next review date: 25-01-2021

Scott is one of the two founders of The Independent Pharmacy. He is a registered pharmacist and the registered manager of our service with the CQC.

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