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Difflam Rinse & Spray

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Order before 4pm for delivery from Fri. 27 Apr.

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Difflam provides powerful, effective relief from sore throats caused by common mouth and throat infections such as thrush, sore throats and oral pain. Difflam comes in two varieties; an oral rinse for gargling and swilling around the mouth, and an oral spray that can be sprayed directly on the area that requires treatment.

Difflam contains benzydamine hydrochloride to help reduce inflammation. Get fast and effective relief from the pain and discomfort caused by mouth and throat infections with Difflam.

Difflam is pain-killing & numbing and is used for the treatment of sore throat, mouth ulcers, gum pain and other oral pains.

Difflam Rinse can be diluted with water if stinging of the mouth occurs when used.


Difflam Orl Rinse

Difflam is an easy to use rinse that can be used to treat symptoms of sore throats, gum pain, mouth ulcers and other oral pains. It contains the active ingredient benzydamine hydrochloride, which is a non-steroidal anti-inflammatory drug that reduces inflammation and pain in the mouth and throat.

The active ingredient in Difflam is an non-steroidal anti-inflammatory drug that acts similarly to ibuprofen. It is a painkiller that can be used to relieve moderate pain and reduce inflammation. It is generally more effective when applied directly to the area suffering from pain.

Many other mouth rinses differ in that they use an anaesthetic to numb pain.

Mint flavoured Difflam oral rinse can be used by adults and children of over 12 years of age. It is easy to use as a mouthwash. It is dispensed in 200ml bottles with a useful measuring cap to help get the dosage just right.

  • Provides rapid relief that lasts a long time, reducing inflammation and pain from a sore throat
  • Can be used to treat discomfort, soreness, and swelling in the throat
  • Is mint flavoured
  • 200 ml bottle with measuring cap to dispense accurate dosages
  • Can be used by adults or children of over 12 years of age
  • Is anti-inflammatory, analgesic and anaesthetic


Difflam Spray provides effective relief from pain, soreness and swelling in the mouth and throat. Its active ingredient benzydamine hydrochloride is an anti-inflammatory which helps heal the pain at its source. Get fast relief from sore throats with this easy-to-use mouth and throat spray.

Difflam Spray delivers the right amount of fast-acting relief where it’s needed. It treats many painful conditions of the mouth and throat including:

  • mouth ulcers, sore throat or gums
  • pain and inflammation after dental surgery
  • throat inflammation following the removal of tonsils or naso-gastric tube insertion
  • sore gums or tongue due to dentures or following dental work


Difflam Spray contains benzydamine hydrochloride, an anti-inflammatory pain reliever. Unlike other sore throat spays it is not a local anaesthetic.


  • handy 30ml spray dispenser travels easily
  • suitable for all ages
  • sugar, lactose and gluten free
  • triple action relief - anti-inflammatory, analgesic anaesthetic


Difflam spray comes in a convenient, portable dispenser that you can keep with you when you are at home or on the go. It can be sprayed directly at the site of the pain and provides a cooling numbness that relieves soreness and swelling.


Pharmacist Tip

Difflam Throat Spray may numb the mouth and throat. Avoid hot food or drinks as you may inadvertently burn yourself.

Difflam Throat Spray provides powerful, effective relief from sore throats caused by common infections and mouth pain. 


Pharmacists tip:

When combined with a paracetamol based product, Difflam oral rinse can help provide relief from more intense pains.

*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

Difflam Oral Rinse

For adults and children of over 12 years of age:

Gargle or rinse around the mouth 15ml of Difflam, using the 15ml measuring cap provided. Spit out the rinse afterwards. Use every 1.5 to 3 hours, as required.

Do not give this medicine to children under 12 years old.

Do not swallow the solution, always spit it out.

Do not bring solution into contact with eyes.

Do not use Difflam for more than seven days without medical advice.

Store between 5-30 degrees C, never freeze the solution, and do not leave bottle uncapped and in direct sunlight.

Keep away from children.

Always read the full instructions before using a new medicine.

Difflam Throat Spray

Apply by spraying directly onto the affected area of the throat or mouth as follows: 

Adults including the elderly and children aged 12 years and over: 

Four to eight puffs, every, one and a half to three hours.

Children 6 - 12 years: 

One puff for every 4kg of body weight. Use up to a maximum of four puffs, every, one and a half to three hours.

Do not exceed the stated dose. 

Not everyone will experience side effects when they take medication, however if you do they can include: 

Occasionally, oral tissue numbness or 'stinging' sensations may occur. Hypersensitivity reactions occur very rarely but may be associated with pruritus rash, urticaria, photodermatitis and occasionally laryngospasm or bronchospasm.

If you are concerned about these effects, or if the product affects you in any other way, stop using it and talk to your doctor or pharmacist. 

The active ingredients contained in this Difflam Spray:

Benzydamine Hydrochloride 0.15% w/v.

Difflam Spray also contains the following inactive ingredients to make up the complete product: 

Ethanol 8.1% w/v FU, Glycerol Ph Eur, Methyl Parahydroxybenzoate Ph Eur, Mouthwash Flavour, Saccharin FU, Sodium Hydrogen Carbonate Ph Eur, Polysorbate 20 Ph Eur, Purified Water Ph Eur.

The active ingredients contained in Difflam Rinse:

Benzydamine Hydrochloride 0.15% w/v.

Difflam Rinse also contains the following inactive ingredients to make up the complete product: 

Ethanol, Glycerol, Saccharin Sodium, Mouthwash Flavour, Polysorbate 20, Methylhydroxybenzoate, E104, E131, Purified Water.

Reading the following warnings carefully will help to ensure Difflam Rinse is appropriate for you. 

  • Avoid swallowing after rinsing. 
  • This product is not recommended for use by children aged 12 years of age and below. 
  • Avoid using this product for more than seven days at a time. 
  • Consult your doctor or pharmacist if the condition does not improve or if it worsens. 
  • Do not contact the eyes with this product. 

Please read all packaging and the Product Information Leaflet before taking any new medicine and inform your doctor of medicines you are taking or intend to take.

Reading the following warnings carefully will help to ensure Difflam Spray is appropriate for you. 

  • Wipe the nozzle with a tissue after use to prevent any blockage. 
  • Consult your doctor or pharmacist if the condition does not improve or if it worsens. 
  • If prolonged stinging occurs in the throat or mouth stop using this product. 
  • Do not contact the eyes with this product. 

Please read all packaging and the Product Information Leaflet before taking any new medicine and inform your doctor of medicines you are taking or intend to take.


We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2/3 day delivery - £2.95
  • Express Tracked Delivery - 1/2 day delivery - £4.45
  • Special Delivery (Guaranteed before 1pm) - £8.95
  • Saturday Guaranteed before 1pm - £10.45

All our orders are sent out using Royal Mail. We always aim to dispatch all orders received before 4pm the same working day. Any orders received after 4pm or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders can be fully tracked in your account.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 5.30pm the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 5.30pm to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 5.30pm to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.



We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Mouth Ulcers?

Visit our advice area or contact our support team

Difflam Rinse & Spray Reviews

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Frequently Asked Questions

  • How to use Difflam Oral Rinse

    Use 15ml of Difflam oral rinse. Pour into the measuring cap, and rinse or gargle in the mouth for up to 30 seconds. Then, spit out the rinse.

    If Difflam oral rinse causes a stinging sensation in the mouth, dilute it with a measuring cap’s worth of water.

  • What is Difflam oral rinse used for?

    Difflam oral rinse can be used to:

    Treat symptoms of throat or mouth infections or conditions

    To reduce inflammation and pain after dental surgery

    To reduce throat inflammation (pharyngitis) after a tonsillectomry or a naso-gastric tube

    To reduce inflammation caused by pharyngitis

    To treat mouth ulcers caused by radiation therapy

  • How does Difflam oral rinse work?

    Difflam oral rinse uses the active ingredient benzydamine hydrochloride to reduce pain and inflammation. Benzydamine hydrochloride is a non steroidal anti-inflammatory drug.

    Benzydamine reduces inflammation and pain by stopping the formation of prostaglandins, which cause these symptoms and are a response to injury or disease.

    Benzydamine is also a local anaesthetic, to reduce pain directly on application.

  • How long does Difflam oral rinse take to work?

    Soreness and inflammation should have reduced within a week of using Difflam oral rinse. If there is no easing of symptoms after this amount of time, consult with a doctor or dentist. You should not use Difflam oral rinse for longer than a week without consulting with a doctor or dentist.

We are a trusted pharmacy

We are regulated by a number of organisations in the UK including the MHRA, GPhC & CQC to ensure we offer the highest level of service to every one of our customers.

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  • 1 Complete a simple health questionnaire
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  • 3 You receive the right treatment or advice
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