Syndol Headache Relief Tablets

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Syndol Headache Relief Tablets
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About Syndol Headache Relief Tablets

Syndol Tablets and Syndol Headache Relief Tablets are for effective and immediate relief from mild to moderate pain caused by headaches, migraines, period pains, toothache and muscle pain. Syndol Headache Relief contains 3 active ingredients: Paracetamol, Codeine and Caffeine. Syndol Tablets have the added benefit of the sedating antihistamine, Doxylamine succinate.

Both tablets are available to buy online from The Independent Pharmacy when you complete a short health questionnaire for our medical team to review. Once approved your order can be delivered to you from the next day.

    • Suitable for age:12 years +
    • Maximum per order:1

    Syndol Headache Relief Tablets information

    • What is Syndol and what is it used for?

      Syndol Headache Relief Tablets are designed to provide effective relief from the pain of headaches or migraines. It is estimated that in The UK over ten million people suffer from headaches and migraines. However, the pain they experience can vary, which makes finding the right treatment very important.

      In addition, Syndol Original Tablets have proven to not only help combat painful headaches they can also be used to relieve mild to moderate pain caused by the following factors:

      • Neuralgia (nerve pain)
      • Period pain
      • Toothache
      • Rheumatic aches and pains

      Both varieties of Syndol should only be used if your pain is not effectively managed by paracetamol, ibuprofen or aspirin alone. They are intended for short-term use only (up to 3 days) as the active ingredients may cause addiction.

      Syndol Headache Relief Tablets contain three active ingredients; paracetamol, codeine and caffeine. Whereas Syndol Original Tablets also contain a sedating antihistamine known as Doxylamine.

      How do Syndol Headache Relief and Syndol Original work?

      Paracetamol is a painkiller that works to relieve mild to moderate pain and fever. It is thought to reduce the production of prostaglandins in the brain and spinal cord. Prostaglandin is a pain-triggering chemical that acts to sensitise nerve endings at the site of trauma. By reducing their production, paracetamol can increase our tolerance to pain. So, even though the cause of the pain will remain, the painful sensation it produces will be reduced.

      Codeine is an opioid painkiller and is slightly stronger than paracetamol. Opioids work by mimicking the action of endorphins, which are the body's natural pain-relieving chemical. Codeine, like endorphins, block the transmission of pain signals being sent from the nerves to the brain. This means that even though the cause of the pain is still there, less pain is actually felt.

      Syndol also contains caffeine, which will act as a weak stimulant. This stimulant can enhance paracetamol’s pain-relieving effects. It can also act to counter the drowsiness that can be caused by codeine.

      Syndol Original Tablets also contain the active ingredient Doxylamine, which is a sedating antihistamine that can help relieve symptoms of allergies such as a blocked nose, sneezing or itchy eyes it can also help to improve the quality and quantity of your sleep if this is impacted by the pain you are experiencing.

      As of March 2015, new drug driver testing has come into force. This allows police to use a roadside test to check for prohibited substances in a driver's saliva. One such prohibited substance is Morphine. Codeine is converted to Morphine in the liver. This means it may be a criminal offence to drive whilst taking Syndol Headache Relief Tablets. You should abstain from driving if you believe this medicine may affect your ability to do so safely.

      People can vary in the way their bodies metabolise codeine. For some, this may lead to an increased chance of experiencing side effects. These can include:

      • Reduced levels of consciousness
      • Sleepiness
      • Slow, shallow breathing
      • 'Pin-point' pupils
      • Lack of appetite
      • Nausea & vomiting
      • Constipation

      If you experience any of the above side effects, stop using Syndol tablets and seek medical advice straight away.

      If you find that Syndol Headache Relief Tablets are not effectively managing your pain symptoms, consult with your doctor or pharmacist.

      Do not take Syndol Headache Relief with any other product that contains paracetamol. An overdose is dangerous and could potentially cause serious damage to the liver and kidneys. Many over-the-counter pain relief treatments, as well as most cough/cold remedies, contain paracetamol. Always check the ingredients of any medicine you buy before taking them at the same time as Syndol. If you are unsure about any medicine or its ingredients, ask your pharmacist for advice.

      Do not take Syndol for longer than 3 days without first consulting your doctor or pharmacist. Taking this medicine regularly can result in building a tolerance to it, which will make it less effective at relieving pain. Prolonged use can also lead to a codeine dependency. As a result, when you stop taking this medicine, it could cause substance withdrawal. This will lead to symptoms, such as irritability and restlessness. If painkillers are used too frequently for headaches, it can often make them worse

      Non-Prescription Alternatives for the treatment of Pain are;

      • Ibuprofen
      • Paracetamol
      • Aspirin
      • Topical Treatments (Ibuprofen gel)
      • Rest the area

      If your pain does not ease or becomes severe, contact your GP or Pharmacist for further advice.

    • Syndol can interact with other medicines. You should not take this medicine if you are taking, have taken recently or plan to take any of the following:

      • Monoamine Oxidase Inhibitors (MAOIs)
      • Antidepressants
      • Phenelzine
      • Tranylcypromine
      • Isocarboxazid
      • Moclobemide
      • Selegiline

      Do not take any other medicine that contains paracetamol with Syndol, as this can easily result in exceeding the maximum daily dosage of paracetamol. Most cough/cold remedies and pain relief medicines contain paracetamol. Always be sure to check the ingredients of any medicine to you intend to take prior to use. Alternatively, ask your pharmacist for advice.

      The amount of codeine contained in Syndol is unlikely to cause drowsiness. However, the chances of experiencing this side effect increases if it is taken with any of the following medicines:

      • Antipsychotics
      • Benzodiazepines
      • Sedating antihistamines
      • Sleeping tablets
      • Strong opioid painkillers
      • Tricyclic antidepressants

      Codeine can reduce muscular activity in the gut, which can oppose the effects of some medicines on the gut. These include; domperidone and metoclopramide.

      Taking codeine together with antimuscarinic medicines can carry an increased risk of experiencing constipation, dry mouth and blurred vision. Examples of antimuscarinics include:

      • Procyclidine
      • Orphenadrine
      • Trihexiphenidyl
      • Oxybutynin
      • Tolterodine
      • Flavoxate
      • Propiverine
      • Trospium
      • Atropine
      • Hyoscine

      If used with antimotility medicines, such as loperamide, codeine can carry a risk of causing severe constipation.

      Medicines such as quinidine, rifampicin and ritonavir are known to reduce the painkilling effects of codeine.

      Colestyramine is known to reduce the absorption of paracetamol from the gut. Because of this, colestyramine should not be taken within an hour of taking a paracetamol containing product, such as Syndol.

      Other medicines that contain the same active ingredients as Syndol Headache Relief include:

      • Solpadeine Max Soluble Tablets
      • Solpadeine Plus Soluble Tablets
      • Veganin Tablets

      Other common medicines that contain both paracetamol and codeine include:

      • Migraleve Yellow Tablets
      • Panadol Ultra
      • Paracodol
      • Codipar
      • Kapake
      • Solpadol
      • Tylex
      • Zapain
    • Swallow with water.

      Adults, the elderly and children over 12 years:

      Two tablets to be taken every four hours as required. Do not take more than eight tablets in any 24 hour period. Do not exceed the stated dose. If symptoms persist, consult your doctor.

      Not suitable for children under twelve years of age.

    • Paracetamol 500mg, Caffeine 30mg and Codeine Phosphate 8mg

    Syndol Headache Relief Tablets reviews

    Syndol Headache Relief Tablets FAQs

    • Syndol tablets provide pain relief from causes such as headache, migraine, toothache, muscle pain and period pain. It is an over-the-counter alternative for cases in which aspirin, paracetamol or ibuprofen have been ineffective.

    • Syndol does not require a prescription. However, take care to always read the label.

    • The active ingredient in Benadryl one A Day tablets is a non-sedating antihistamine called cetirizine. Allergy symptoms occur due to the activity of mast cells. These cells are responsible for the immune system’s reaction to foreign particles. When an allergen enters the body, mast cells release substances such as histamine. This binds to H1 receptors, which causes an inflammatory response, leading to congestion and watery eyes.

      Antihistamines work in different ways. Whereas some other medicines inhibit the release of histamine, cetirizine prevents histamine from reaching its H1 receptors. This blocks the body’s inflammatory response to allergens, easing the frustrating symptoms of hayfever and other allergies.

    • In recent years Syndol has been reformulated. Its current formulation contains paracetamol (500mg), codeine (8mg) and caffeine (30mg). It no longer contains an ingredient called doxylamine, which is an antihistamine

    • Syndol is manufactured by Sanofi. Sanofi have been working with both the manufacturing plants and regulatory authorities to determine whether the original Syndol formulation can be brought back. Whether this will happen cannot be confirmed, but we will keep you updated as to any decisions made.

    • Doxylamine is a non-habit forming antihistamine. It works by blocking the production of histamine and acetylcholine in the body. This action can cause drowsiness, which can help aid sleep. The current formulation of Syndol, which has been approved by the regulatory authorities, does not contain doxylamine. This means the product causes less drowsiness.

    • Anugesic HC Cream should be applied twice each day, and after each bowel movement.

      Before use, wash your hands and the affected area thoroughly with water. Gently dry the skin around the anus to prevent further irritation.

      For internal use, a nozzle is provided, which screws on to the top of the tube. Gently insert the tip of the nozzle into the anus, and squeeze the tube such that a small amount of cream is released. Withdraw the nozzle carefully, then use warm water to thoroughly wash both the nozzle and your hands.

      Anugesic HC suppositories should be inserted into the rectum.

    • Syndol is unsuitable for the following types of people:

      • Those with respiratory problems (e.g. shallow breathing, asthma, chronic obstructive pulmonary disease
      • Those with an allergy to any of this medicine’s ingredients
      • Those at risk of paralytic ileus (an intestinal blockage caused by nerve or muscle problems)
      • Those with increased pressure within the skull
      • Those with a liver enzyme CYP3D6 which converts codeine into morphine – this will increase the risk of side effects
      • Women who are pregnant or breastfeed
      • Anyone under the influence of alcohol
      • Children under the age of 12
      • Adolescents (under the age of 18) who have had their tonsils removed
      • Adolescents (under the age of 18) with breathing problems or heart conditions
    • Although each tablet contains only a small amount of codeine, it may still cause drowsiness. Do not drive or operate machinery until you know that Syndol will not make you feel tired or dizzy. The liver converts codeine into morphine – it is illegal to drive if this medicine is present in your saliva.

      Side effects of this medicine can vary significantly depending on how your body breaks down codeine. The range of possible side effects includes drowsiness, dizziness, shallow breathing, reduced appetite, constipation, nausea and small pupils.

      Syndol contains a small amount of caffeine. Take care if also consuming caffeine from other sources, as this may lead to unwanted side effects including anxiety, irritability, insomnia or further headaches.

      Avoid other medicines containing paracetamol while using Syndol.

      Do not exceed the recommended dose of Syndol, as it may be harmful to the kidneys and/or liver. Seek medical attention if you substantially exceed the recommended dose.

      Avoid drinking alcohol while using Syndol, as it may increase your chance of an overdose of paracetamol.

    • Syndol is only suitable for adults and children over the age of 12 years. It should not be taken by children under 12. Always read the product packaging and patient information leaflet prior to use.

    • Syndol Headache relief Tablets are only for short-term use (up to 3 days). They are suitable for treating acute moderate pain that is not sufficiently relieved by paracetamol, ibuprofen or aspirin alone. Syndol can effectively provide relief from; headaches, migraines and other pain.

    • You should take 2 tablets every 4 hours when required. Never take more than 8 tablets in a 24 hour period. Syndol should only be taken for a maximum of 3 days. If you need to it for longer than 3 days, see your doctor or pharmacist for advice. Taking painkillers for headaches for longer than three days can actually make them worse.

    • Syndol should not be taken at the same time as other products containing paracetamol. Always read the patient information leaflet for further contraindications.

    • No, Syndol Headache Relief Tablets can be purchased over-the-counter without a prescription.

    Still unsure about this treatment?

    Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

    A small collection of medicines; A tube of orange ointment, a bottle of pills, and a tub of creamA doctor wearing glasses, with a stethoscope around his neck and an orange clipboard, welcoming a new customer with a wave

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