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Buy Phenergan 10mg & 25mg Tablets Online

  • Suitable for age:16 years +

Phenergan Information

  • What is Phenergan?

    At The Independent Pharmacy, you can buy Phenergan tablets online in either 10mg or 25mg strengths, by filling in a short online consultation for our pharmacy team.

    Promethazine hydrochloride is the active ingredient in Phenergan. Promethazine is a drowsy antihistamine medication which relieves the symptoms of a number of conditions, including allergies, rashes, nausea and is also known for its sedative effect.

    Phenergan is classed as a pharmacy-only medicine in the UK. It comes in packs of 56 tablets and is produced by the global manufacturer, Sanofi.

    What is Phenergan used for?

    Phenergan Tablets are used to treat the following conditions:

    • For treatment of adults with difficulty sleeping (insomnia)
    • To treat allergic reactions such as hay fever or rashes (like nettle rash or hives)
    • To treat or stop you feeling sick (nausea) or being sick (vomiting) such as travel sickness
    • To ease coughing or a runny nose

    Please note, we are only able to supply Phenergan tablets for use in patients aged 16 and over online.

    How does Phenergan work?

    Promethazine hydrochloride (the active ingredient in Phenergan) works by blocking the receptors of histamines and dopamine to reduce the impact of allergies and nausea but it also works directly on the brain which makes you feel relaxed.

    Promethazine hydrochloride also works by blocking acetylcholine receptors which help to reduce a runny nose or a cough.

    Phenergan for anxiety

    Phenergan tablets are sometimes taken by people when suffering from anxiety due to its sedative effect. Phenergan tablets can be taken in the short term to treat adults with sleeping difficulties that may be caused by anxiety.

    Although Phenergan can be used short-term to aid sleep during situational anxiety, Phenergan is not licensed to be used to treat anxiety or other mental health conditions.

    How long does Phenergan take to work?

    You will notice that Phenergan tablets should start to take effect around 20 minutes after they are taken and the effect can last for 12 - 24 hours.

    Phenergan is a long-acting antihistamine and, as such, only usually needs to be taken once daily, normally at night.


    Patient Information Leaflet

    Phenergan 10mg Patient Information Leaflet:

    Phenergan 25mg Patient Information Leaflet:

  • Phenergan warnings

    Phenergan tablets are known to interact with some other medications so it is essential that if you are currently taking any other medication, including herbal medications that you talk to a doctor before commencing treatment.

    Do Not take Phenergan tablets if in the last 2 weeks you have taken or are currently taking monoamine oxidase inhibitors (MAOIs) that are used for treating depression. If you are not sure ask your doctor or pharmacist

    Check with a doctor or pharmacist before taking Phenergan tablets if any of the following apply to you:

    • You have difficulty breathing, wheezing, tightness in the chest (asthma) or an infection in your lungs (bronchitis).
    • You have epilepsy
    • You have any serious heart problems
    • You have liver or kidney problems
    • You have a stomach blockage or difficulty passing water (urine).
    • You have hearing problems.
    • You have increased pressure in the eye (narrow-angle glaucoma).
    • You have had something called Reye’s Syndrome or possible Reye’s Syndrome signs include being sick and confused following a viral illness.
    • You are allergic to promethazine hydrochloride or any other ingredients contained in Phenergan tablets.

    If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Phenergan Tablets.

    Phenergan in pregnancy and breastfeeding

    Most manufacturers of antihistamines advise avoiding their use during pregnancy and while breastfeeding; however, there is no evidence to suggest they cause abnormalities.

    Antihistamines are known to be passed into breast milk in varying amounts but are not known to be harmful.

    Use of antihistamines in the 2 weeks before birth is not advised due to adverse effects on the newborn baby such as irritability, paradoxical excitability, and tremors.

    Phenergan and alcohol

    Do not drink alcohol while you are taking Phenergan Tablets. This is because it can affect the way the medicine works.

    Phenergan and driving

    Phenergan causes drowsiness. Drowsiness may affect the performance of skilled tasks (e.g. cycling or driving); sedating effects may be enhanced by alcohol.

    If you feel drowsy when taking Phenergan tablets DO NOT drive or operate machinery.

  • Phenergan Dosage

    If you are taking Phenergan tablets your dose will depend on the reason you are taking it. Phenergan tablets can be purchased from The Independent Pharmacy in either 10mg or 25mg doses.

    Phenergan is is licensed for people over the age of 5 years, however, we are only able to supply people aged 16 years and over online.

    Phenergan tablets are for oral use only.

    Phenergan 10mg

    To treat allergies:

    • Children 2-5 years: Phenergan Elixir is recommended for this age group.
    • Children 5-10 years: either 1-2 tablets at night or 1 tablet twice a day.
    • Children over 10 years & adults: Start with 1 tablet twice a day, can be increased to 2 tablets 3 times a day if necessary.

    To treat travel sickness:

    • Children 2-5 years: Phenergan Elixir is recommended for this age group.
    • Children 5-10 years: Take 1 tablet the night before the journey. This may be repeated after 6-8 hours if necessary.
    • Children over 10 years & adults: Take 2 tablets the night before the journey. Can be repeated after 6-8 hours if needed.

    For short-term sedation:

    • Children 2-5 years: Phenergan Elixir is recommended for this age group.
    • Children 5-10 years: Take 2 tablets as a single night time dose.
    • Children over 10 years and Adults: Take 2-5 tablets as a single night time dose

    Phenergan 25mg

    For allergies (such as hay fever, rashes and hives):

    • Children 2-5 years: Phenergan Elixir should be given in this age group
    • Children 5-10 years: A single tablet (25mg) given at night (DO NOT give more than 25mg each day)
    • Children over 10 years and adults (including the elderly): Start with one tablet (25mg) taken at night. This may be increased to a maximum of one tablet (25mg) twice a day if necessary

    For treatment and prevention of feeling sick or being sick (such as travel sickness):

    • Children 2-5 years: Phenergan Elixir should be given in this age group
    • Children 5-10 years: Phenergan Elixir or Phenergan 10mg Tablets should be given in this age group
    • Children over 10 years and adults (including the elderly): A single tablet (25 mg) to be taken the night before the journey. This may be repeated after 6-8 hours if necessary.

    For short term sedation:

    • Children over 10 years and adults (including the elderly): One or two tablets (25mg-50mg) taken at night

    What if I take too many Phenergan tablets?

    If you or your child takes over the stated dose of Phenergan tablets you should speak to a doctor immediately or go to a hospital emergency department straight away.

    DO NOT drive yourself as Phenergan tablets can make you drowsy. Take your medicine pack with you so the doctor knows what you have taken.

    What if I forget to take my Phenergan tablets?

    Do not take a double dose to make up for a missed dose.

    If you are taking Phenergan tablets for an allergy then take your dose as soon as you remember and then carry on as before.

    If you are taking Phenergan for sleeping difficulties miss this dose and take your next dose the following evening.

    How long can I take Phenergan for?

    Phenergan should not be taken for more than 7 days without the advice of a healthcare professional. If after 7 days your condition has not improved or your symptoms have become worse, talk to your doctor or a pharmacist.

  • Phenergan ingredients

    Each tablet contains either 10mg or 25mg of the active substance, promethazine hydrochloride

    The non-active ingredients include lactose, maize starch, povidone, magnesium stearate, polyethylene glycol, Opaspray (contains titanium dioxide-E171, hypromellose-E464 and indigo carmine aluminium lake blue-E132) and hypromellose

  • Phenergan Side Effects

    Like all medicines, Phenergan Tablets can cause side effects, although not everybody gets them. If you experience any adverse reactions stop taking Phenergan Tablets immediately. If the side effects continue, seek advice from a pharmacist or a doctor.

    Common side effects include:

    • Feeling tired throughout the day
    • Nightmares
    • Dizziness and difficulties concentrating
    • Headaches

    Some people may also develop an increased sensitivity to sunlight.

    In those over 65, it is more common to develop anticholinergic effects such as:

    • Dry mouth
    • Increased thirst
    • Difficulty passing urine
    • Blurred vision

    If you experience any of the following severe side effects seek medical advice from a doctor straight away:

    • Yellowing of the skin or whites of the eyes, this may indicate liver problems
    • An allergic reaction such as; a rash, swallowing or breathing difficulties, swelling of the lips, tongue, face, throat
    • Muscle stiffness or shaking
Phenergan reviews

Phenergan FAQs

  • This medicine should not be taken if you are taking or have taken in the last 14 days, a monoamine oxidase inhibitor (MAOI), egphenelzine, trancylcypromine, or isocarboxazid.
    If this medicine is taken in combination with any other medicine that causes drowsiness, there may be an increased effect of drowsiness.

    If taking a treatment involving histamines (such as for leukaemia), or betahistines (used for treating Ménière's disease), then this medicine should not be used as antithistamines may produce the opposite effect.

  • Phenergan contains the active ingredient, promethazine, a sedating antihistamine. It prevents the actions of histamine.

    Histamine is a substance produced by the body as part of the immune system. It causes the symptoms of allergic reactions such as inflammation of the airways or skin, rashes, nasal congestion, and itching of the skin, eyes or nose. Promethazine prevents histamine from binding to its receptors in various parts of the body and this stops it from causing the symptoms of allergies.

    Histamine can also cause more severe reactions such as anaphylaxis. Promethazine treats localised allergies such as hay fever and nettle rash, as well as anaphylaxis.

    Promethazine also blocks histamine receptors in the brain in an area called the called the vomiting centre. The vomiting centre causes feelings of sickness and the vomiting reflex. It is activated when it receives nerve messages from the vestibular system in the middle ear about the body’s position.

    When something disturbs the vestibular system, such as head movements when travelling by boat or car, nerve signals are sent from the middle ear to the vomiting centre. The effect can cause motion sickness symptoms. By blocking the histamine receptors in the brain’s vomiting centre, Promethazine prevents disturbances in the middle ear from activating the vomiting reflex, thus preventing motion sickness symptoms.

  • Dosage and frequency will depend on the patient’s age and condition. Follow the instructions in the leaflet or packaging provided with this medication, or your doctor’s instructions.

    • Do not exceed the recommended dose.
    • Phenergan tablets and elixir can be taken either with or without food. The tablets should be swallowed whole with water.
    • Seek medical advice if your symptoms continue despite treatment from your doctor or pharmacist.
    • Do not use this medication for longer than seven days without advice from your doctor.
  • Side effects while taking Phenergan can include: gastro-intestinal disturbances (diarrhoea, nausea, constipation, vomiting or abdominal pain), dry mouth, loss of appetite, tiredness, sleepiness, restlessness, dizziness and blurred vision.

    You can find more details about the side effects in our Side Effects section.

  • Do not use Phenergan if you:

    • Are pregnant or breastfeeding
    • Have an allergy promethazine or any ingredients in Phenergan.
    • Have an allergy to sulphites, phenothiazines or benzoates.
    • Have experienced jaundice caused by other phenothiazine derivatives.
    • Take medicines that interact with Phenergan, including: monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, sedatives and hypnotics, barbiturates and opioid analgesics.

    You can find more information in our Warnings section.

  • Some medications interact with Phenergan. You should not take them while you are being treated with Phenergan unless advised by your doctor. These medications include: monoamine oxidase inhibitors (MAOIs), sedatives and hypnotics, tricyclic antidepressants, barbiturates and opioid analgesics.

    You can find more information in our Warnings section.

  • Store Phenergan in a cool, dry place below 25°C.

  • Phenergan can make your skin extra sensitive to sunlight. Steps should be taken to avoid sunburns. Avoid using sunbeds and going outside in strong sun. When outside, wear clothing and use sunscreen.

Still unsure about this treatment?

Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

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