Panadol Extra Advance Tablets

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Buy Panadol Extra Advance Tablets Online in the UK

from £3.79

Panadol Extra Advance tablets can start to work in as little as 10 minutes and are primarily used to treat the symptoms of:

  • Headaches
  • Migraines
  • Backaches
  • Rheumatic pains
  • Toothaches
  • Menstrual cramps

Who Is Panadol Extra Advance Tablets Suitable For?

Suitable for age: 18 +
Suitable for pregnancy?No
Suitable for breastfeeding?No
Maximum per order:3

About Panadol Extra Advance Tablets

What are Panadol Extra Advance Tablets?

Panadol Extra Advance Tablets are designed to alleviate headaches, migraines, backaches, rheumatic pains, toothaches, and menstrual cramps. They also reduce the discomfort and aches associated with colds and flu.

These tablets consist of two active ingredients. Paracetamol serves as a pain reliever and also lowers fever, whilst caffeine enables the paracetamol to get to work faster.

How to take Panadol Extra Advance Tablets

Adults and children aged 16 years and over: Swallow 2 tablets every 4 hours as needed. Do not take more than 8 tablets in 24 hours.

Children aged 12 - 15 years: Swallow 1 tablet every 4 hours as needed. Do not take more than 4 tablets in 24 hours. Do not take more frequently than every 4 hours. Do not give to children under 12 years.

Never take more medicine than the label tells you to.

Try to avoid consuming too much caffeine whilst taking this medicine.

If you take too much of this medicine you should speak to your doctor straight away, even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage.

Panadol Extra Advance Tablet ingredients

Active ingredients: Paracetamol 500mg and Caffeine 65mg.

Other ingredients: Sodium methyl (E 219), sodium ethyl (E 215) and sodium propyl (E 217) parahydroxybenzoates.

Panadol Extra Advance Tablet side effects

Like all medicines, Panadol Extra Advance Tablets can have side effects but not everybody gets them. In some instances, very rare cases of serious skin reactions have been reported.

Stop taking the medicine and tell your doctor immediately if you experience:

  • Allergic reactions which may be severe such as skin rash and itching sometimes with swelling of the mouth or face or shortness of breath
  • Skin rash or peeling, or mouth ulcers
  • Breathing problems. These are more likely if you have experienced them before when taking other painkillers such as ibuprofen and aspirin
  • Unexplained bruising or bleeding
  • Nausea, sudden weight loss, loss of appetite and yellowing of the eyes and skin

Panadol Extra Advance Tablet warnings

Do not take this medicine:

  • If you have ever had an allergic reaction to paracetamol, caffeine or to any of the other ingredients
  • If you are taking any other prescription or non prescription medicines containing paracetamol to treat pain, fever, symptoms of cold and flu, or to aid sleep.

Ask your doctor before you take this medicine:

  • If you have liver or kidney problems
  • If you are underweight or malnourished
  • If you regularly drink alcohol
  • If you have a severe infection as this may increase the risk of metabolic acidosis (for example: deep, rapid, difficult breathing – feeling sick (nausea), being sick (vomiting) – loss of appetite)

Panadol Extra Advance Tablets reviews

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Daniel Hurley
Written by Daniel Hurley
Clinical Governance Lead
MPharm IP PgDip Pharm Pract
GPhC 2078790

Dan is a GPhC-Registered Pharmacist and Clinical Governance Lead at The Independent Pharmacy. Dan is committed to making healthcare more accessible and helping patients feel confident, informed and supported when navigating decisions about their health and wellbeing. An extensive professional background allows Dan to provide clear, practical and patient-focused advice, helping people cut through jargon and feel more confident in their care.


MPharm
GPhC 2079324

Scott is a co-founder and GPhC-registered pharmacist at The Independent Pharmacy. With 14 years of experience, Scott leads our digital strategy and is dedicated to ensuring online healthcare adheres to the highest safety standards. His areas of expertise include understanding digital healthcare delivery in the UK, particularly the regulatory frameworks, and how technology can be used to increase access to healthcare while reducing risk. Scott believes care should be individualised to meet the needs of the patient. He is also highly experienced in the digitalisation and automation of pharmacy dispensing and fulfilment.

Published 5 April 2024
Updated 30 September 2025
Reviewed 5 April 2024
Next review 4 April 2026