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Ciprofloxacin 500mg Tablets

*The brand supplied may vary. Please contact us if you require a specific brand.

Ciprofloxacin 500mg Tablets

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Order before 3pm for delivery from Fri. 30 Jul and Mon. 02 Aug.

Ciprofloxacin Information

  • Age: 18 years +

    Maximum per order: 1

  • Pregnancy: N/A

    Breastfeeding: N/A

How does Ciprofloxacin treat travellers' diarrhoea?

Travellers' diarrhoea can be a real pain, especially if you are in a location that is far away from any kind of medical treatment. Ciprofloxacin is an effective antibiotic treatment for killing the bacteria associated with travellers' diarrhoea.

Ciprofloxacin is a kind of antibiotic known as a “quinolone antibiotic”. It is in no way related to penicillin. It is important to note that Ciprofloxacin should only be used to treat the symptoms of travellers' diarrhoea – it should not be used as a preventative measure.

Ciprofloxacin can be used to treat a wide variety of bacterial infections, one of which is travellers' diarrhoea. As an antibiotic, Ciprofloxacin will attack the dangerous bacteria infecting your body, preventing them from spreading and ultimately killing them off. When Ciprofloxacin attacks the bacteria, it prevents them from producing an enzyme that they require to live and reproduce. This leaves the bacteria wide open to attack from your body’s natural defences.

Ciprofloxacin can effectively reduce the duration of your traveller’s diarrhoea, as well as the symptoms associated with it. This effectiveness can be enhanced by the anti-diarrhoea drug loperamide. For best results you should take Ciprofloxacin twice a day for three days.


What countries is Ciprofloxacin recommended for use in TD?

It is an ideal solution for travellers and works on the common types of bacteria found in most countries around the world, except South Asia (such as India and Pakistan) and South East Asia (including Thailand, Vietnam, Cambodia, Laos, & Myanmar) - for these areas, Azithromycin is the preferred antibiotic


What is travellers' diarrhoea?

Common throughout the world, travellers' diarrhoea is a condition in which stools will be passed frequently. This is usually as a result of consuming some kind of food or drink which has been contaminated with bacteria, viruses, or parasites.

The condition can be very unpleasant and can get in the way of day to day life – this is especially true when travelling. Though uncomfortable, the condition is nothing to worry about and will usually pass within a few days.

Important Information 

Your symptoms should begin to improve within 24 hours of taking Ciprofloxacin. Its effectiveness can be increased when used in conjunction with Loperamide. If used in conjunction with anti-sickness tablets, such as Avomine, you can help to reduce your fluid loss and general discomfort.

Ciprofloxacin tablets should not be taken if:

  • You are allergic to any of the ingredients
  • You have kidney problems
  • You have epilepsy
  • You suffer from muscles weakness
  • You have a history of irregular heart rhythms

When taking Ciprofloxacin you skin will become more sensitive to UV rays from the sun. For this reason it is advised that you avoid exposure to direct sunlight, as well as UV lamps, as much as possible. When you must go into the sun it is recommended that you used sun protection. If you notice any changes in your skin as a result of being in sunlight you should contact your doctor immediately.

In some cases, patients will develop a condition known as crystalluria in which they pass small crystals in their urine. If you notice this you should make sure you are drinking plenty of water and contact your doctor if necessary.

Ciprofloxacin may give a false test result for tuberculosis.

Always inform your doctor as to any medications you are currently taking or have recently taken. Some substances within the blood can be increased if using Ciprofloxacin, these are:

  • Agomelatine
  • Zolpidem

Take special care if you are using Ciprofloxacin at the same time as any of the following medications:

  • Methotrexate (for certain types of cancer, psoriasis, rheumatoid arthritis)
  • Vitamin K antagonists (e.g. warfarin)
  • Probenecid (for gout)
  • Theophylline (for breathing problems)
  • Phenytoin (for epilepsy)
  • Metoclopramide (for nausea and vomiting)
  • Tizanidine (for muscle spasticity in multiple sclerosis)
  • Anti-arrhythmics medications
  • Tricyclic antidepressants
  • Some antimicrobials (that belong to the group of macrolides)
  • Ropinirole (for Parkinson’s disease)
  • Cyclosporin (for skin conditions, rheumatoid arthritis and in organ transplantation)
  • Some antipsychotics such as olanzapine and clozapine

Blood levels of certain medications can be increased when using Ciprofloxacin, these include:

  • Lidocaine (for heart conditions or anaesthetic use)
  • Pentoxifylline (for circulatory disorders)
  • Caffeine
  • Duloxetine (for depression, diabetic nerve damage or incontinence)
  • Sildenafil (e.g. for erectile dysfunction)

Certain medications can also reduce the effects of Ciprofloxacin, these include:

  • Antacids
  • Omeprazole
  • Mineral supplements such as calcium, iron and magnesium
  • Sucralfate
  • Polymeric phosphate binder such as sevelamer and lanthanum carbonate

If you must take any of these medications then it is advised that you wait at least 2 hours before or after taking Ciprofloxacin.

You should always read all available packaging and product information before beginning a new medication.

Pharmacist Tip:

Avoid dairy products as much as possible while taking Ciprofloxacin. You should also avoid anything which contains high levels of magnesium, calcium, iron, or aluminium such as antacids or supplements at least 2 hours before or after each dose of Ciprofloxacin.

OTC (over the counter medication) alternative for Travellers' Diarrhoea

In some more simple cases travellers' diarrhoea can be treated with over-the-counter medicines. These medicines include Loperamide (Imodium) and re-hydration sachets (Dioralyte). Using these products together will help ease the symptoms, this will help as your body is trying to fight off the infection. You must also ensure you remain hydrated so take on as much fluids as possible during this time, as dehydration is the most dangerous consequence of travellers' diarrhoea. 

*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

Ciprofloxacin dosage for travellers' diarrhoea

How to take Ciprofloxacin tablets (antibiotics)

  • Take one tablet twice daily, roughly 12 hours apart.
  • You should always continue the course until it is complete unless otherwise directed by a doctor.
  • You should start taking Ciprofloxacin as soon as you recognize the symptoms of traveller’s diarrhoea such as diarrhoea, nausea, sickness, and stomach cramps.
  • You should try to avoid food and drink containg high levels of calcium or iron (e.g. dairy products, red meat) at least 2 hours each side of taking Ciprofloxacin. You should also try to avoid antacids for the duration of your treatment.

How to take Loperamide capsules (anti-diarrhoeals)

  • Take two capsules at the onset of diarrhoea, followed by a further capsule after each loose bowel movement.
  • You should never take more than 8 capsules in 24 hours.

How to take Dioralyte sachets (rehydration sachets)

  • Dissolve the contents of one sachet in roughly 200mL of fresh drinking water. Where fresh drinking water is unavailable, you should use water that has been freshly boiled and cooled.
  • The solution should be made up immediately before use and consumed within one hour. If it is possible to refrigerate the mixture it can be stored for up to 24 hours.

Ciprofloxacin side effects

Most people will not experience any side effects when using Ciprofloxacin, however approximately 1 in 10 people might experience the following symptoms:

  • Nausea
  • Diarrhoea
  • Joint pain

Please read the Patient Information Leaflet for a full list of side effects.

If you have any concerns regarding these side effects, or any of the information listed in the Patient Information Leaflet, speak to your doctor or pharmacist.

Ciprofloxacin ingredients

Ciprofloxacin 500mg tablets contain one active ingredient:

  • Ciprofloxacin hydrochloride

Ciprofloxacin 500mg tablets also contain several inactive ingredients:

  • Maize starch
  • Microcrystalline cellulose
  • Sodium starch glycolate
  • Anhydrous colloidal silica
  • Magnesium stearate
  • Hypromellose
  • Macrogol 400
  • Titanium dioxide (E171).

Ciprofloxacin warnings

Before using Ciprofloxacin you should read the following warnings carefully:

Ciprofloxacin should not be used if you or your child:

  • Have ever had an allergic reaction to any of the ingredients listed above
  • Have ever had an allergic reaction to any other quinolone antibiotics
  • Are currently taking tizanidine

Before using Ciprofloxacin you should talk to your doctor if you:

  • Have ever had any issues with your kidneys
  • Suffer from neurological conditions such as epilepsy
  • Have had problems with your tendons when using other antibiotics
  • Have diabetes as this can increase the risk of hypoglycaemia
  • Have myasthenia gravis (a type of muscle weakness)
  • Have heart problems
  • Have a family history of prolonged AT intervals (from an ECG)
  • Have a salt imbalance
  • Have a slow heart rhythm
  • Have a weak heart of history of heart attacks
  • Have a family member with a glucose-6-phosphate dehydrogenase (G6PD) deficiency as this can lead to anaemia

You should cease usage and contact your doctor if any of the following occurs:

  • Severe allergic reaction to the drug. Symptoms include: tightening of the chest, dizziness, sickness, and feeling faint.
  • You experience any loss of vision or impairment of sight.
  • You experience pain and even swelling in the joints (particularly your Achilles tendon – this is more likely to happen if you are older.
  • You have an epileptic seizure or any other neurological conditions such as stroke or ischemia.
  • It is possible that you may develop some adverse psychological reactions when using Ciprofloxacin for the first time. If you already have depression or psychosis then Ciprofloxacin may make these symptoms worse. In some rare cases this can lead to risks of suicidal thoughts and eventually suicide.
  • You experience hypoglycaemia (a lack of sugar in the bloodstream).
  • If you develop severe or bloody diarrhoea as a result of using Ciprofloxacin.
  • Symptoms such as jaundice, loss of appetite and dark urine could indicate liver damage.
  • If you have a fever or your general condition deteriorates you may have reduced levels of white blood cells.

Always inform doctors as to any medications you have taken.

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2 - 3 day delivery - £2.95
  • Express Tracked Delivery - 1 - 2 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail & DPD orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email, in your online account and from any notifications from your courier.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail


  • Fully tracked delivery
  • SMS & email notifications
  • Four-hour delivery window
  • Change delivery date directly with Royal Mail
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local Post Office or Royal Mail Customer Service Point.

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.




  • Fully tracked delivery
  • SMS & email notifications
  • One-hour delivery window
  • Change delivery date directly with DPD
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local collection point.

DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Travellers' Diarrhoea?

Visit our advice area or contact our support team

Ciprofloxacin 500mg Tablets Reviews

Unsure about a treatment?
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Frequently Asked Questions

  • Is Ciprofloxacin the best antibiotic for the country I am travelling to?

    Ciprofloxacin is the best antibiotic to use in most regions around the world. Ciprofloxacin should not be used in South Asia, for example India and Pakistan, or South East Asia, such as Cambodia, Vietnam, Thailand, Laos, & Myanmar. In these regions the recommended treatment is Azithromycin due to resistance to Ciprofloxacin.

  • What exactly is Ciprofloxacin?

    Ciprofloxacin is an antibiotic that belongs to the quinolone family. As an antibiotic it is used as a treatment for bacterial infections, especially within the chest, stomach, and urinary tract.

  • How does Ciprofloxacin kill bacteria?

    Ciprofloxacin kills harmful bacteria within your body by attacking their cells directly. By preventing the bacteria from producing an enzyme known as DNA-gyrase, Ciprofloxacin is able to stop the bacteria from spreading, causing them to die.

  • Can Ciprofloxacin be used by everybody?

    Women who are pregnant or currently breast feeding should not use Ciprofloxacin. You should also avoid Ciprofloxacin if you are allergic to any of the ingredients contained within it.

    You should consult your doctor before taking Ciprofloxacin if:

    • You are over 60
    • You have had an organ transplant
    • You have poor kidney function
    • You have a history of brain or nervous system disorders
    • You are taking corticosteroids.
  • What should I avoid when using Ciprofloxacin?

    Dairy products such as milk, cheese, and yogurt should be avoided, as well as any excess calcium in the form of supplementation. Other supplements, such as magnesium, iron, and aluminium should be taken at least two hours before or after Ciprofloxacin.

  • When should I take Ciprofloxacin?

    You can take Ciprofloxacin twice a day for a maximum of three days. Ciprofloxacin should be taken only once diarrhoea has started, not as a preventative measure.

  • When should I seek professional help?

    You should see an improvement in your symptoms within 24 hours of taking Ciprofloxacin. If your symptoms do not improve, or worsen, you should seek medical advice. You should also seek medical advice if any of these things occur:

    • Excessive diarrhoea or vomiting, leading to dehydration
    • Bloody or mucus-filled stools
    • Severe abdominal pain
    • High fevers or severe headaches



  • Additional medicines to treat diarrhoea:

    You can use Loperamide alongside Ciprofloxacin in order to reduce the symptoms of diarrhoea. At the same time, make sure you are drinking plenty of fluids, even if you are continuing to vomit – at least 3 litres a day. Eat simple food such as bread and rice as much as possible. You should also pay special attention to your personal hygiene to avoid the spreading of the bacteria.

Authored By:

A photo of Dr Donald Grant

Dr Donald Grant

MB ChB DRCOG MRCGP Dip.orth.med

Published on: 17-01-2017

Last modified on: 17-01-2021

Dr Don Grant is a GP with over 30 years experience and is the Clinical Advisor at The Independent Pharmacy

Reviewed By:

A photo of  Scott McDougall

Scott McDougall


Reviewed on: 17-01-2021

Next review date: 17-01-2023

Scott is one of the two founders of The Independent Pharmacy. He is a registered pharmacist and the registered manager of our service with the CQC.

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