

Xepin 5% Cream - Relief From Eczema Itching
Effectively relieves intense itching associated with eczema
Blocks histamine to reduce the urge to scratch
Helps break the itch-scratch cycle
Apply 3-4 times daily for continuous relief
Available after a quick online consultation
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Buy Xepin 5% Cream Online - Eczema Relief
If you live with eczema, you’ll know all too well how frustrating the itch-scratch cycle can be. You scratch for a moment of relief, only for the itch to come back stronger. So you scratch again, and the cycle continues. That’s where Xepin Cream can help.
Xepin is an antipruritic (anti-itch) cream containing 5% doxepin hydrochloride. It works by blocking histamine, the chemical in your body that causes itching, helping to calm irritated skin and break the cycle of discomfort.
Xepin Cream offers long-lasting relief and helps you get back to feeling comfortable in your skin.
To get started, you’ll just need a quick consultation with one of our healthcare professionals to make sure it’s the right treatment for you. Once approved, you can order online and start managing your eczema symptoms fast.
This is a generic medicine and the manufacturer of the treatment supplied may vary from the treatment image above, depending on availability. Please contact us once you've placed your order if you require a specific brand and we will do our best to accommodate your request.
About Xepin 5% Cream
Xepin Cream is a prescription-strength white moisturising cream formulated to relieve itching and skin discomfort caused by eczema/dermatitis. It comes in 30g tubes and contains 5% doxepin hydrochloride, which helps calm your skin and reduces the urge to scratch.
It’s designed to help you feel more comfortable and give you long-lasting relief from the symptoms of eczema.
How Does Xepin Cream Work?
Xepin Cream works by blocking the effects of histamine - a chemical in the body that triggers itching and inflammation. By calming your skin’s response, it helps reduce the constant urge to scratch, which is an important part of managing eczema.
This action helps break the itch-scratch cycle, giving your skin a chance to heal and providing long-lasting relief from irritation. It’s a targeted way to soothe inflamed skin and make daily life more comfortable.
How To Use Xepin Cream
Before you start using Xepin Cream, read through the patient information leaflet. It gives you all the information about how to use it and the potential side effects.
You should apply a thin layer of cream to the affected areas three to four times daily, being careful to avoid your eyes and any tight coverings or bandages.
It’s really important you make sure the cream doesn’t cover more than 10% of your body – it can increase the chances of you feeling drowsy or getting a dry mouth. As a rough guide 10% is an entire arm, the front and back of one leg or half your torso. The 10% can also be made up of smaller patches.
If you use too much, wash it off straight away and contact your doctor if you’re worried.
Ingredients
The active ingredient in Xepin Cream is doxepin hydrochloride 5%. The cream also contains the following inactive ingredients: sorbitol solution, cetyl alcohol, glyceryl stearate and titanium dioxide.
Always read the patient leaflet and check the ingredients to make sure you’re not allergic to anything before you begin using the cream.
Side Effects
Like any medication, Xepin Cream can cause side effects though not everyone will experience them. You may feel drowsy or sleepy when you use it, particularly in the first few days as your body adjusts but this can settle with continued use. You may also notice burning or stinging where you apply the cream. This is normal and should ease quickly.
More rarely you could experience a dry mouth, vision changes, difficulty passing urine, a fever or headache, dizziness, nausea, vomiting, diarrhoea or constipation and changes in taste. If you experience any of these, stop using the cream and speak to your doctor.
Warnings
While Xepin Cream is safe for many people if you have certain conditions, you should avoid using it or speak to your doctor first.
Do not use the cream if you’re allergic to any of the ingredients and check with your healthcare provider or doctor before starting if you have glaucoma, urinary retention, liver disease, depression or heart disease.
Avoid using the cream if you’re pregnant, or think you might be, unless specifically advised to by your doctor. Avoid drinking alcohol when using the cream too as it may increase the risk of side effects.
Xepin Cream FAQs
What Is Eczema And How Does Xepin Help?
Eczema is a common skin condition that causes dry, red, inflamed, and intensely itchy skin. It can flare up due to triggers like stress, allergens, weather changes, or irritants, leading to discomfort and the constant urge to scratch. This scratching can damage your skin further, making symptoms worse and prolonging flare-ups.
Xepin Cream helps manage eczema by targeting the itch. It contains 5% doxepin hydrochloride, an antihistamine that works by blocking histamine, a chemical in your body responsible for causing itching. By calming this response, Xepin helps reduce your urge to scratch, giving your skin a chance to heal and break free from the frustrating itch-scratch cycle.
With regular use as directed, Xepin can give you much-needed relief and make it easier to manage everyday life with eczema.
Who Can Use Xepin 5% Cream?
Xepin Cream is designed to be used by people who are suffering from eczema and as directed by their doctor. You should avoid using the cream if you’re allergic to any of the ingredients and you should speak to your doctor first if you suffer from glaucoma, urinary retention, liver disease, depression or heart disease. You should also avoid using it if you’re pregnant or think you might be, unless your doctor specifically directs you otherwise.
How Much Xepin Cream Should I Apply?
You should apply a thin layer where you have patches of eczema three to four times a day, but you should never cover more than 10% of your body surface area. Ideally, you should use no more than 3g of cream per application and no more than 12g per day.
This is because using too much cream can increase the risk of you feeling drowsy or getting a dry mouth. As a rough guide 10% is one arm or the back and front of the top half or your leg, or half your torso. If you’re worried you’ve used too much, wash it off and speak to your doctor.
Will Xepin Cream Make Me Drowsy?
Some people do feel drowsy or dizzy when they use the cream, especially at the start of treatment when their body isn’t used to it. If you feel drowsy or less alert you should avoid driving or using heavy machinery until you know how the cream affects you.
You should also avoid drinking alcohol as this can make the drowsiness worse. Always use the cream exactly as prescribed by your doctor.
Can I Use Xepin With Other Eczema Treatments?
You can use Xepin Cream alongside other moisturising (emollient) creams to soothe your skin and keep it hydrated. It’s best to wait 30 minutes between applying Xepin Cream and other hydrating creams so you don’t dilute its effects.
If you’re using other steroid skin creams or antihistamines to treat your eczema it’s best to speak to your doctor or pharmacist first to make sure they’re safe to use together.
How Long Does It Take For Xepin To Work?
Your skin may start to feel better and you’ll notice less itching within 24 hours of using the cream although it can take a few days for the full effects to be felt. Everyone’s skin responds differently so it’s important to use the cream as directed.
If you don’t see any improvements after seven days of regular use, or if symptoms get worse, then speak to your doctor or pharmacist – they may ask you to continue for a little longer or suggest an alternative treatment.
Can I Use Xepin During Pregnancy Or Breastfeeding?
While Xepin Cream is generally safe for most people you shouldn’t use it if you’re pregnant or breastfeeding unless your doctor says it’s okay. This is because there’s not enough evidence to show it’s safe for pregnant women.
If you’re suffering with eczema, speak to your doctor first who may be able to suggest treatments that are safer for you and your baby. Always follow medical advice and never start a treatment during pregnancy without professional guidance.
What Is The Difference Between Xepin And Other Anti-Itch Treatments?
Xepin works differently to steroid creams or antihistamine tablets. While steroid creams reduce inflammation and oral antihistamines target histamine throughout your body, Xepin tackles it locally, blocking histamine directly in the affected skin.
This makes it particularly effective for targeting eczema without the potential side effects of long-term steroid use like thinning skin. If you need focused, prescription-strength eczema treatment, it’s a helpful alternative.
Can I Cover The Treated Area After Applying Xepin?
It’s best not to cover any areas treated with Xepin with bandages, dressings or tight clothing unless your doctor specifically says you should. Covering the skin can increase how much of the cream is absorbed and may raise the risk of side effects like drowsiness or skin irritation.
Leave your skin to breathe after applying the cream and let it absorb fully before you do cover the area with clothing.
How Do I Buy Xepin Cream Online?
Xepin Cream is a prescription only, which means you’ll need a brief consultation with one of our medical professionals first. Don’t worry - consultations are discreet, confidential and designed to ensure it’s the right treatment for you. Once approved you can easily arrange for the cream to be delivered straight to your door.
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