The Independent Pharmacy
Spedra Tablets (50mg, 100mg & 200mg)

Spedra Tablets (50mg, 100mg & 200mg)

from £27.50
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About Spedra Tablets (50mg, 100mg & 200mg)

Spedra tablets are one of the most popular treatments for Erectile Dysfunction (ED) in the UK. They can take effect as soon as 20 minutes after use and help you to achieve an erection and allow you to maintain one for a window of 4-5 hours.

Spedra can help you have a normal sex life again, however, to make sure it is the right treatment for you it is important that you discuss the causes and symptoms of your ED first, before you buy.

The Independent Pharmacy offers a fast & free, online consultation before dispensing Spedra tablets.

Order Spedra online and get immediate ED relief as quickly as the very next day.

  • Suitable for age:18 Years +
  • Maximums per order:
    Spedra 50mg Tablets12
    Spedra 100mg Tablets12
    Spedra 200mg Tablets12
  • Consultation required?Yes
    This treatment requires an online consultation for review by our medical team. The decision to supply the specific treatment and quantity requested will be based on whether our medical team are satisfied that it will be safe, appropriate, and effective.
Type of medicinePDE-5 inhibitor
Works byPromoting blood flow towards the penis, which results in a heightened ability to maintain erections
Active ingredientAvanafil
Effective within20 minutes
Pack size4 tablets
Strength50mg, 100mg, 200mg
Common side effectsHeadache, Flushing, Light Headedness, and rarely a Stuffy Nose or Indigestion
ManufacturerA. Menarini Farmaceutica Internazionale
Use with alcoholNo known issues

We stock 3 different variants of Spedra Tablets (50mg, 100mg & 200mg)

Spedra Tablets (50mg, 100mg & 200mg) information

  • What are Spedra tablets?

    Spedra tablets are an ED medication. Spedra works by promoting blood flow towards the penis, which results in a heightened ability to maintain erections. This blood flow will only occur during sexual stimulation, so Spedra does not allow you to skip the foreplay.

    Spedra is available in three doses, 50mg, 100mg and 200mg. It is recommended you start on 100mg, but all of the doses can be prescribed depending on your needs, by our qualified, UK-based doctors.

    Avanafil as an ED treatment

    The active ingredient of Spedra tablets is the drug avanafil (avanafil is also sold under the brand name Stendra in the US). This is a PDE-5 inhibitor, a drug which tackles ED by increasing the blood flow to your penis once you have become aroused. Other PDE-5 inhibitors are: Cialis, Levitra, and Viagra.

    Read about the differences between Spedra vs Viagra in more detail here.

    Is avanafil available in the UK?

    Avanafil is available with a prescription in the UK from your doctor/GP or a registered online pharmacy. You will be required to complete a medical consultation in order to buy avanafil and Spedra tablets.

    What is Spedra 100mg?

    Spedra comes in 50mg,100mg, and 200mg dosages. It is recommended that you start by taking the 100mg tablets.

    Spedra 200mg tablets are the highest dosage available and are prescribed to men who have tried lower dosages or other ED treatments without success.

    A Spedra 200mg tablet should be strong enough to treat almost all cases of ED. However, like all ED medication, there is a chance of little or no effect, particularly if it is one of the first times the medicine is being used. If a certain dose of Spedra isn't working, it is advised that you try it at least eight times before deciding to switch to another dose or medicine.

    If side effects such as headaches or flushing appear, and persist after several uses of the medicine, you might want to consider another treatment or a reduced dosage.

    Read more about the possible Spedra side effects here.

    Does Spedra work?

    Spedra treats ED by dealing with the physical causes that prevent a man from achieving an erection – reduced blood flow to the penis as a result of blocked or narrow arteries. ED can also be caused by psychological reasons, such as anxiety or depression. It is possible that Spedra can help in achieving an erection when ED is caused by psychological symptoms. In these cases, it is recommended that advice from a doctor or therapist is sought for a long-term solution.

    How long does it take for Spedra to work?

    Spedra is one of the fastest solutions for ED available – it can take effect in just 20 minutes, and this can last for up to 4 or 5 hours. However, if you have recently eaten prior to taking Spedra then it can take up to 90 minutes for the medication to work.

    What are the most common side effects of Spedra?

    The following side effects can appear when using Spedra:

    Common – may appear in up to 1 in every 10 people:

    • Flushing
    • Nasal congestion
    • Headache

    If any of these concern you, or Spedra causes any other side effects, consult with a doctor or pharmacist.

    Not everyone will experience side effects, read this guide for more information on Spedra side effects.

    Is Spedra better than Viagra?

    The active ingredient of Viagra is sildenafil citrate. While both Spedra and Viagra allow you to achieve and then maintain an erection for up to 5 hours, Viagra takes an hour to take effect, while Spedra becomes effective after just 20 minutes.

    Read this guide for more information on Spedra vs Viagra.

    Which erectile dysfunction treatment is best?

    There are a large number of ED treatments available and the best one for you will depend on your medical circumstances and personal requirements:

    • Cialis – Best if you want a long-lasting ED treatment and a well-known brand
    • Sildenafil – Best if you want a cheaper alternative to Viagra
    • Spedra – Best if you want a fast-acting ED treatment
    • Tadalafil – Best if you want a long-lasting and cheaper alternative to Cialis
    • Viagra – Best if you want a well-known ED treatment that lasts 4-5 hours
    • Viagra Connect – Best if you do not have a prescription for ED medication
    • Vitaros – Best if you have found other ED medication to be ineffective

    For more information on the different medications available, check out our Compare ED Treatments table.

    Spedra tablets (50mg, 100mg & 200mg) reviews

    When looking for reviews of Spedra tablets it is important that you check the websites where the reviews are posted. Some of the different things for you to consider when assessing the website(s) hosting Spedra reviews are:

    • What is the posting process – how are the reviews regulated?
    • Does the website employ registered medical professionals to monitor and curate the posts?

    If you are in doubt about the accuracy of the Spedra reviews you are reading, remember that it is always best to seek advice from a registered medical professional.

  • Spedra dosage

    • You should take one Spedra tablet around 30 minutes before sex
    • Spedra can take up to 60 - 90 minutes to take effect in some men if it is taken on a full stomach after a large meal
    • Spedra can produce an effect for up to 4 – 5 hours
    • You should never take more than one tablet for erectile dysfunction (Spedra, Viagra, Cialis, or Levitra) in a 24-hour period
    • You should take Spedra on an empty stomach and try to limit your alcohol intake to ensure it remains effective

    Spedra does not always work for everyone the first time they use it. If this is the case you should not give up, guidance states that you should try Spedra at least 8 times before trying an alternative ED treatment. If you find Spedra tablets effective and do not experience any serious side effects you can request a repeat order via your online account. If you followed the above guidance and still find Spedra ineffective you may wish to increase the strength of your Spedra tablets, or alternatively try a different medicine such as Viagra, Cialis or Levitra.

  • Spedra ingredients

    Each Spedra tablet contains avanafil as the active ingredient in either 50mg, 100mg or 200mg.

    Spedra tablets also contain the following inactive ingredients: mannitol, fumaric acid, hydroxypropylcellulose, low substituted hydroxypropylcellulose, calcium carbonate, magnesium stearate and ferric oxide yellow (E172).

  • Spedra side effects

    Not everyone will experience side effects from Spedra, although they are more likely if you have never taken Spedra before or if you take Spedra 200mg due to their high strength. If you do experience side effects from Spedra tablets they may include

    • Headache, flushing
    • Lightheadedness
    • Rarely a stuffy nose
    • Indigestion

    Spedra has a small risk of nausea, vomiting, diarrhoea, and skin rash as with all medicines. Please read the Patient Information Leaflet enclosed with your medicines for a full list of side effects.

    Read this guide for more information on Spedra side effects.

  • Spedra warnings

    Do not take Spedra:

    • If you are allergic to avanafil or any of the other ingredients of this medicine
    • If you are taking “nitrate” medicines for chest pain (angina), such as amyl nitrite or glyceryl trinitrate. Spedra can increase the effects of these medicines and severely lower your blood pressure
    • If you are taking medicines for HIV or AIDS such as ritonavir, indinavir, saquinavir, nelfinavir or atazanavir
    • If you are taking medicines for fungal infections such as ketoconazole, itraconazole or voriconazole or certain antibiotics for bacterial infections, such as clarithromycin or telithromycin
    • If you have a serious cardiac problem
    • If you have had a stroke or heart attack in the last 6 months
    • If you have an irregular heartbeat (“arrhythmia”) or heart problems that run in your family, as shown on a heart tracing (ECG)
    • If you have low blood pressure or high blood pressure not controlled by medicines
    • If you have chest pain (angina) or you get chest pain during sexual intercourse
    • If you have a serious liver or kidney problem
    • If you have loss of vision in one eye due to not enough blood getting to your eye (non-arteritic ischemic optic neuropathy [NAION])
    • If certain serious eye problems run in your family (such as retinitis pigmentosa).

    Do not take Spedra if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Spedra.

    Warnings and precautions

    Talk to your doctor or pharmacist before taking Spedra:

    • If you have heart trouble. It may be risky for you to have sexual intercourse
    • If you suffer from priapism, that is a persistent erection lasting 4 hours or more. This can happen in men with conditions like sickle cell disease, multiple myeloma or leukaemia.
    • If you have a physical condition that affects the shape of your penis (such as angulation, Peyronie’s disease or cavernosal fibrosis)
    • If you have any bleeding disorder or active peptic ulceration.

    If any of the above apply to you talk to your doctor or pharmacist before taking Spedra. Check with your doctor or pharmacist if you are not sure.

    Problems with your sight or hearing

    Some men taking medicines like Spedra have had problems with their sight and hearing – see “Serious side effects” in section 4 for more details. It is not known if these problems are related directly to Spedra, other diseases that you may have or a combination of factors.

    Spedra with food and alcohol

    Grapefruit juice can increase exposure to the medicine and should be avoided within 24 hours prior to taking Spedra.

    Drinking alcohol at the same time as taking Spedra may increase your heart rate and lower your blood pressure. You may feel dizzy (especially when standing), have a headache or feel your heart beating in your chest (palpitations). Drinking alcohol may also decrease your ability to get an erection.

Spedra Tablets (50mg, 100mg & 200mg) Price Comparison

View all the available prices for Spedra Tablets (50mg, 100mg & 200mg) from The Independent Pharmacy

Spedra 50mg Tablets

Save up to 34%
  • 1 x 4 tablets
    £27.50 per pack
  • 2 x 4 tablets
    £24.50 per pack
    Save £6.00
  • 3 x 4 tablets
    £23.00 per pack
    Save £13.50
  • 4 x 4 tablets
    £22.00 per pack
    Save £22.00
  • 5 x 4 tablets
    £21.00 per pack
    Save £32.50
  • 6 x 4 tablets
    £20.00 per pack
    Save £45.00
  • 7 x 4 tablets
    £19.50 per pack
    Save £56.00
  • 8 x 4 tablets
    £19.00 per pack
    Save £68.00
  • 10 x 4 tablets
    £18.50 per pack
    Save £90.00
  • 12 x 4 tablets
    £18.00 per pack
    Save £114.00

Spedra 100mg Tablets

Save up to 29%
  • 1 x 4 tablets
    £32.50 per pack
  • 2 x 4 tablets
    £30.00 per pack
    Save £5.00
  • 3 x 4 tablets
    £28.00 per pack
    Save £13.50
  • 4 x 4 tablets
    £26.00 per pack
    Save £26.00
  • 5 x 4 tablets
    £26.00 per pack
    Save £32.50
  • 6 x 4 tablets
    £25.00 per pack
    Save £45.00
  • 7 x 4 tablets
    £25.00 per pack
    Save £52.50
  • 8 x 4 tablets
    £24.00 per pack
    Save £68.00
  • 10 x 4 tablets
    £23.50 per pack
    Save £90.00
  • 12 x 4 tablets
    £23.00 per pack
    Save £114.00

Spedra 200mg Tablets

Save up to 27%
  • 1 x 4 tablets
    £42.00 per pack
  • 2 x 4 tablets
    £37.00 per pack
    Save £10.00
  • 3 x 4 tablets
    £36.25 per pack
    Save £17.25
  • 4 x 4 tablets
    £35.25 per pack
    Save £27.00
  • 5 x 4 tablets
    £34.75 per pack
    Save £36.25
  • 6 x 4 tablets
    £33.75 per pack
    Save £49.50
  • 7 x 4 tablets
    £32.75 per pack
    Save £64.75
  • 8 x 4 tablets
    £31.50 per pack
    Save £84.00
  • 10 x 4 tablets
    £30.99 per pack
    Save £110.10
  • 12 x 4 tablets
    £30.25 per pack
    Save £141.00
Spedra Tablets (50mg, 100mg & 200mg) reviews

Spedra Tablets (50mg, 100mg & 200mg) FAQs

  • In adults 18 years and over, the dose of Spedra is one tablet when required, around 30 minutes before sex. You should not take more than one Spedra tablet, or other erectile dysfunction treatment, in a 24-hour period.

  • There are three dosages of Spedra available. These are 50mg, 100mg, and 200mg tablets. The 100mg option is recommended for men beginning Spedra treatment. The other dosages are for men who find the response to the 100mg tablets either too weak or too strong.

  • Spedra can take as little as 15 minutes, or as long as 90 minutes, to work. This variation depends on how full the stomach is. On an empty stomach, absorption will be very fast, whilst on a full stomach it can take a while.

  • You should take Spedra on an empty stomach where possible. If you have recently eaten, especially if it was a large meal, this may delay the absorption of the tablet and mean it can take 60 - 90 minutes to reach its full effect.

  • Spedra is a much faster treatment than Viagra. Viagra must be taken 1 hour before sex, whilst Spedra can work as quickly as 15-30 minutes after consumption.

    Both treatments last a similar amount of time – about 4 - 5 hours.

    Note that this does not mean that you will maintain an erection for this amount of time, but that your ability to achieve and maintain an erection will be improved during this time.

    Taking Spedra after a large meal can delay its effects.

    Read this guide for more information on Spedra vs Viagra.

  • Both treatments last around the same amount of time, being 4-6 hours.

  • As Spedra is a more recent product, it is difficult to know if it has less side effects than Viagra. Viagra has been used for a long time, and proven to be effective and safe. If you are concerned about side effects, using Viagra will be a simpler choice.

  • Yes, as long as you are buying from a website that is a legally operating and regulated pharmacy it is perfectly safe to buy Spedra online. The Independent Pharmacy is an NHS Online Pharmacy based in Bristol and has all the necessary regulation to be able to safely provide convenient access to genuine prescription treatments through our Online Pharmacy & Online Doctor.

    If you’re unsure, here’s more information on how to buy medicine safely.

  • Spedra should only be purchased from websites registered with the Care Quality Commission and the General Pharmaceutical Council. These sites will be regulated, ensuring they sell genuine Spedra in a safe manner.

    Buying Spedra tablets online from The Independent Pharmacy is simple: just select 'Start Consultation' above. You will then need to fill in a simple health questionnaire so our GPs & Pharmacists can ensure it is safe for us to supply your Spedra to you. It all takes around 3 minutes and your treatment can be delivered to your door.

  • There are many advantages to buying Spedra tablets online, some include:

    • It's quick & easy - there is no need to spend time at the doctor or pharmacy.
    • Fast delivery - We offer same-day dispatch before 4pm and fast delivery to your address of choice with Royal Mail.
    • Great prices - we are able to offer very competitive prices and we guarantee to beat any other Online Doctor service.
    • Tons of information - we provide all the information you could need on Spedra and other ED treatments, in easy to digest formats, at a time to suit you.
  • Yes, we understand that sometimes you want to get your treatment as soon as possible. If ordered before 4pm Monday to Friday, Spedra tablets are available for next day delivery.

  • You should not take any other erectile dysfunction treatments or tablets with Spedra or within 24 hours of taking it. If you find that Spedra tablets are not as effective as you would like, you should consider increasing your dose if on a lower strength.

  • Spedra tablets are a prescription-only erectile dysfunction. For that reason, to ensure the safety of our patients and the legal operating of our pharmacy, we only supply a maximum of 32 tablets at one time. This is normally enough for 2 - 3 months of treatment, which can then be easily reordered if necessary.

  • The following side effects can appear when using Spedra:
    Common – may appear in up to 1 in every 10 people: Flushing, nasal congestion, headache
    If any of these concern you, or Spedra causes any other side effects, consult with a doctor or pharmacist.
    Not everyone will experience side effects.

  • Inform your doctor or pharmacist of any medicines you are taking and intend to take.

    Medicines such as Spedra can alter the effects of other medicines, and other medicines can also alter the effect of Spedra. Spedra can affect these medicines, and so you should not combine them:

    • Nitrate medicines such as amyl nitrate or glyceryl trinitrate, for chest pain.
    • Medicine for AIDS or HIV, such as indinavir, ritonavir, saquinavir, atazanafir, or nelfinavir.
    • Medication for fungal infections such as itraconazole, voriconazole, or ketoconazole.
    • Certain antibiotics such as clarithromycin or telithromycin

    If you are using any of the following medications, inform your doctor or pharmacist before using Spedra:

    • Alpha-blockers for lowering of the blood pressure or prostate problems
    • Medications for treating arrhythmia, such as procainamide, quinidine, sotalol or amiodarone
    • Antibiotics such as erythromycin
    • Primidone, phenobarbital, or carbamazepine for epilepsy
    • Riociguat Moderate CYP3A4 inhibitors which may prevent Spedra from breaking down inside the body. These include aprepitant, diltiazem, amprenavir, fosamprenavir, fluconazole, and verapamil

    Do not combine Spedra with other treatments for erectile dysfunction, such as tadalafil, vardenafil, or sildenafil. Before using Spedra, make sure to read all the instructions and packaging.

  • Spedra should only be purchases from websites registered with the Care Quality Commission and the General Pharmaceutical Council. These sites will be regulated, ensuring they sell genuine Spedra in a safe manner.

  • Spedra is under patent in the UK, and so there are no generic unbranded Spedra drugs available. Any website claiming to offer cheaper and generic unbranded Spedra is breaking the law.

  • In clinical trials, Viagra provides effective treatment for erectile dysfunction in about 80% of men. Spedra only provides effective treatment to about 60% of men. Viagra is a well known and trusted treatment for erectile dysfunction. However, Spedra is a significantly faster acting treatment.

    If speed is important to you, then you should see if Spedra is an effective treatment for you. If Spedra does not produce the effect that you desire, then you should consider using Viagra instead.

    It is recommended that you discuss treatment options and side effects with a doctor before using any new medicines.

    To see a full list of treatments for erectile dysfunction, take a look at our erectile dysfunction treatment page.

  • Other treatments for erectile dysfunction should be used in conjunction with Spedra, or taken within 24 hours of using Spedra.

    If Spedra 100mg tablets are not satisfactory, consider using Spedra 200mg tablets.

  • The active ingredient in Spedra is avanafil. Spedra 100mg tablets contain 100mg of avanafil.

    Spedra is a type of medicine known as a PDE-5 inhibitor that is used in treating erectile dysfunction (ED) in men. Spedra is the most recent medicine that has been approved for ED treatments. Spedra is a medicine for men who suffer from ED, much like other well known treatments such as Cialis, Viagra, and Levitra.

    Erectile dysfunction (ED) is a condition where the man cannot achieve an erection that can be used for sexual activity. When using Spedra, sexual stimulation is still required in order to achieve an erection.

    Spedra was released to in May 2014 and under exclusive licence to be marketed only by Menarini. The wholesale price of Spedra is competitive with other branded treatments for ED, though there are some unbranded treatments (such as sildenafil, which is identical to Viagra) which are cheaper.

  • Avanafil takes effect in as little as 20 minutes and lasts as long as 5 hours.

  • Avanafil costs from £4.50 per tablet, making Spedra cheaper than Cialis, Levitra, Viagra, and Vitaros.

  • Trials have shown that 72% of people who used avanafil have been able to successfully engage in sexual intercourse within minutes of taking the medication.

Haven’t found the right treatment for you?

No problem. Ask our medical team for free, impartial advice.

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