

Axsain 0.075% Cream
- Targets nerve-related pain right at the skin’s surface
- Eases post-shingles discomfort
- Helps diabetic nerve pain
- Simple topical application
- Fast, discreet delivery
- 100% UK-based pharmacy
- Free advice and support
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Axsain 0.075% Cream - Available Online
Axsain 0.075% Cream is a capsaicin treatment for relieving nerve pain near the skin surface, including post-shingles pain and diabetic nerve pain in the hands and feet. Following a short consultation, one of our expert UK-registered prescribers will review your information and advise if this product is suitable for you.
Who Is Axsain 0.075% Cream Suitable For?
Axsain 0.075% Cream Information
What Is Axsain 0.075% Cream?
Axsain 0.075% Cream contains capsaicin, which relieves nerve pain near the skin. It’s used to treat post-shingles pain and diabetic nerve damage in hands and feet.
Can I Use Axsain 0.075% Cream?
Axsain 0.075% Cream is for adults with nerve pain near the surface of the skin, including:
- Pain after shingles, also known as post-herpetic neuralgia
- Painful diabetic nerve damage in the hands and feet
It will not be suitable if you have broken or irritated skin.
How Does Axsain 0.075% Cream Work?
Axsain 0.075% Cream contains capsaicin, the active ingredient found in chilli peppers.
When applied to the skin, capsaicin works by affecting the nerve endings that send pain signals to the brain. With regular use, it reduces the amount of a chemical involved in transmitting pain signals. Over time, this helps decrease the intensity of nerve pain in the treated area.
Alternatives to Axsain 0.075% Cream
If Axsain 0.075% Cream is not suitable for you, other capsaicin treatments may be considered.
These include:
- Zacin 0.025% Cream, which contains the same active ingredient (capsaicin) but at a lower strength
The most appropriate treatment will depend on your symptoms and medical history. Our prescribers will review your consultation and advise if Axsain or an alternative treatment is suitable for you.
How To Use Axsain 0.075% Cream
- Apply a thin layer to the affected area.
- Gently rub it in until it’s absorbed.
- Use 3–4 times a day, with a gap of at least 4 hours, as directed by your prescriber.
- Wash your hands after applying, unless you are treating your hands.
Ingredients
Active ingredient: capsaicin 0.075%
Other ingredients: purified water, sorbitol solution, isopropyl myristate, cetyl alcohol, white soft paraffin, glycerol stearate, PEG-100 stearate and benzyl alcohol.
For the most up-to-date list of ingredients, please check the Patient Information Leaflet inside the box.
Side Effects
Like all medicines, Axsain 0.075% Cream may cause side effects.
The most common side effect is a warm, burning or stinging feeling where the cream is applied. This is usually mild to moderate and usually reduces with continued use.
Other side effects may include:
- Redness or irritation where you’ve applied the cream.
- Vapours may cause brief eye, nose or throat irritation, coughing, sneezing, breathlessness or worsening asthma.
If the irritation is severe or does not improve, stop using the cream and speak to your clinical team.
Warnings
Please read the following warnings carefully before use.
- Do not use on broken or irritated skin.
- Do not use if allergic to capsaicin or any ingredient.
- Keep away from eyes, nose and mouth.
- Wash hands after use, unless treating your hands.
- Speak to a healthcare professional if pregnant or breastfeeding.
- Avoid hot baths or showers before or after use.
- Stop use if severe irritation or rash occurs.
For all warnings and side effects, please see the Patient Information Leaflet.
Axsain 0.075% Cream FAQs
What is Axsain Cream used for?
Axsain Cream is used to relieve nerve pain near the surface of the skin. It’s used to treat post-shingles pain and diabetic nerve damage in hands and feet.
Is Axsain Cream discontinued?
Axsain 0.075% Cream has experienced supply interruptions in the past, and availability may vary depending on the manufacturer.
At the time of writing, it is available through The Independent Pharmacy following an online consultation. A UK-registered prescriber will review your information and confirm whether treatment is appropriate.
If Axsain 0.075% Cream is not available, speak to our expert clinical team who will be able to suggest alternative treatments.
Is Axsain Cream the same as capsaicin cream?
Axsain is a brand of capsaicin cream. It contains capsaicin 0.075%. Other capsaicin creams are available in different strengths, including 0.025%.
What’s the difference between Axsain and Zacin Cream?
Both Axsain and Zacin contain capsaicin. Axsain contains 0.075% capsaicin, while Zacin contains 0.025%.
Axsain Cream is licensed to treat post-shingles nerve pain and painful diabetic nerve damage in the hands and feet.
Who should not use capsaicin cream?
You should not use Axsain 0.075% Cream if:
- You are allergic to any of the ingredients
- You have broken or irritated skin
You should speak to your clinical team about using Axsain Cream if you are pregnant, planning a baby or are breastfeeding.
What is the best brand of capsaicin cream?
There is no single “best” capsaicin cream. The most appropriate strength and formulation depends on your diagnosis and medical history. A prescriber will assess this during your consultation.
What are the negative effects of capsaicin?
Like all medicines, Zacin 0.025% Cream may cause side effects.
The most common side effect is a brief burning feeling when applied. This should reduce with continued use.
How often should I apply capsaicin cream?
Capsaicin cream should be applied 4 times a day, with a gap of at least 4 hours between each application.
Is capsaicin bad for your skin?
Capsaicin cream is not usually harmful to your skin when used as directed.
However, many people notice a warm or burning sensation when they first apply it. This reaction is common and usually improves as your skin adjusts to the treatment.
The cream should only be applied to healthy, unbroken skin. If you develop severe irritation or a rash, stop using it and speak to a healthcare professional.
How long does it take for capsaicin to stop burning skin?
A warm or burning feeling is common when you first start using capsaicin cream. This usually improves after a few weeks as your skin gets used to the treatment. Most people find the sensation fades over time, and many no longer notice it after several weeks of regular use.
How long does capsaicin take to work?
You may feel some benefit a few days after you start applying capsaicin cream, but it may take 6–8 weeks before you get the full effect.
How effective is capsaicin cream?
In a clinical trial, capsaicin cream was significantly better than placebo for treating both neuropathic and musculoskeletal pain with 57–60% of users experiencing at least 50% pain reduction within 4–8 weeks.
Where to apply capsaicin cream?
Capsaicin cream should be applied to clean, dry, unbroken skin over painful muscles or joints. Use a pea-sized amount 3–4 times daily, with a gap of at least 4 hours between applications. Wash hands immediately afterwards, unless you are treating your hands.
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