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Propranolol 40mg Tablets

*The brand supplied may vary. Please contact us if you require a specific brand.

Propranolol 40mg Tablets (84 tablets )

Order before 3pm for delivery from Sat. 07 Aug.

Product Information

  • Age: 18 years +

    Maximum per order: 1

  • Pregnancy: Not suitable

    Breastfeeding: Not suitable

Beta-blockers like propranolol have been used to prevent migraines for more than 25 years and remain an effective option for reducing the number of attacks. Propranolol is the drug of choice for migraine prevention and is the most commonly used beta-blocker.


  • You suffer between 2-8 headaches a month.
  • Your headaches are less frequent but more prolonged (more than 2 days) or you have severe attacks leading to substantial disability.
  • You cannot take other prescription migraine treatments or you have other conditions.
  • Your migraines are predictable in occurrence.
  • You have tried other prescription treatments but they have not worked, or you are using them often.
  • You have suffered unwanted effects from other migraine treatments.
  • You have taken regular treatments which could be considered as overuse. Medication overuse is defined as the use of combination analgesics, opioids or triptans ten days each month or use of simple analgesics (paracetamol, non-steroidal anti-inflammatory drugs [NSAIDs] or aspirin) 15 days a month or more.

One of the major reasons people do not succeed with preventative or prophylactic drugs is that they have not taken the medication long enough, or have taken it in an insufficient dosage.

Patients should start treatment with Propranolol at a low dose of 40mg twice a day for a month. If needed, you can gradually increase the dose up to 240mg, in divided doses, until you reach your desired effect or until unwanted effects interfere. A long-acting form of 160mg capsules is also available.

Propranolol has been proven effective at reducing migraines by 50% in 35-60% of patients, however it has no impact on the severity or duration of attacks. It may take a few weeks to take effect. For this reason, you should continue to use painkillers and prescription treatments if you develop a migraine. Sumatriptan, other migraine tablets and a variety of pain killers are available online to compliment your Propranolol treatment

Usually, a patient should start with a low dosage of Propranolol in order to test response, then gradually increase it as needed.

Unfortunately, many physicians discontinue treatment before the drug has had a chance to work. Inderal may take six to twelve weeks to be effective with increased dosages as the weeks go by.

Migraine headaches can be debilitating if patients have difficulty controlling or minimising the symptoms. However, migraines can be moderated by the avoidance of triggers, lifestyle changes and abortive treatment. For patients whose migraines do not respond to such measures, prophylactic prevention may be needed.

Alternate OTC (over the counter) Medication for Migraines

There are some over the counter medications that can be used initially to try and combat migraine pain and nausea. Some of the products include;

  • Paracetamol
  • Ibuprofen
  • Aspirin
  • Buccastem M to help with nausea.
*Prescription medicines are supplied subject to a medical consultation at the discretion of a doctor.

Take ONE to TWO tablets, ONCE or TWICE daily to prevent migraines or as directed by your GP. See GP if migraines continue or worsen.

Common (may affect up to 1 in 10 people)

Side effects while taking Propranolol 40mg can include:

Tiredness, cold extremities, difficulty sleeping, slow or irregular heartbeat, Raynaud’s syndrome and/or nightmares

If you are concerned about these effects, or if the product affects you in a different way, stop using it and consult your doctor or pharmacist.

Active ingredient:

Propranolol hydrochloride

Inactive ingredients:

Lactose, magnesium stearate, maize starch, stearic acid, hypromellose (E464), carmoisine (E122), polysorbate, titanium dioxide (E171) and iron oxide (E172)

Read the following warnings to ensure you are selecting an appropriate product.

Do not take propranolol and tell your doctor if you have any of the following conditions:

  • Untreated/uncontrolled heart failure or are in shock caused by heart problems
  • Low blood pressure
  • Slow heart rate
  • Blood circulation problems
  • Diabetes mellitus (low blood sugar levels may be hidden by this medication) 
  • Heart conduction or rhythmic problems
  • Increased blood acid
  • Are on a strict fasting diet
  • Prinzmetal’s angina
  • Untreated phaeochromocytoma (high blood pressure due to a tumor near the kidney)
  • Asthma or other breathing difficulties

Tell your doctor or pharmacist before taking propranolol if you:

  • Have a weak heart or first degree heart block.
  • Suffer from muscle weakness (myasthenia gravis).
  • Have kidney or liver disease.
  • Have had allergic reactions.
  • Have had allergic reactions.
  • Suffer from blood circulation problems.
  • Suffer with or have had psoriasis.
  • Suffer from Raynaud’s disease (cold sensations in the extremities) or intermittent claudication (narrowing of arteries in the legs causing pain while walking).
  • Have symptoms of hyperthyroidism.
  • Are a smoker.

Inform your doctor/pharmacist if you take or have recently taken:

  • Verapamil and diltiazem (to treat heart diseases).
  • Disopyramide, quinidine and amioadarone (to treat irregular heartbeat (arrhythmia).
  • Ergotamine derivatives (to treat migraine).
  • Adrenaline (epinephrine, used in anaphylactic shock).
  • Diabetes treatments, including insulin.
  • Lidocaine, propafenamine or flecanide (for irregular heartbeat or as a local anasethetic).
  • Non-Steroidal Anti-Inflammatory drugs (NSAIDs).
  • Indometacin.
  • Chlorpromazine (for mental illness).
  • Cimetidine (to treat stomach ulcers).
  • High blood pressure medications (clonidine, moxonidine, alpha-blockers, methyldopa or hydralazine).
  • Digitalis glycosides such as digoxin (for heart conditions).
  • Monoamine-oxidase inhibitors, imipramine or fluvoxamine.
  • Warfarin.
  • Rizatriptan.
  • Barbituates.
  • Rifampicin.
  • Theophylline.
  • Diuretics.

Please read all packaging and the Product Information Leaflet before taking any new medicine and inform your doctor of medicines you take or intend to take.

Delivery & Shipping Information

Please note that due to the current situation with COVID-19, Royal Mail are experiencing some delays. This may mean that your order takes longer to arrive than you would normally expect. We are working hard to ensure that, where possible, all orders placed before 15:00 are still dispatched the same working day.


UK Orders

We offer FREE standard tracked delivery on orders over £40.

The following delivery options are available:

  • Standard Tracked Delivery - 2 - 3 day delivery - £2.95
  • Express Tracked Delivery - 1 - 2 day delivery - £4.45
  • DPD Next Day - 1 - 2 working days - £6.95
  • Special Delivery (Guaranteed before 21:00) - £8.95
  • Saturday Guaranteed before 21:00 - £10.45

Important Delivery Information

All our orders are sent out using Royal Mail (unless stated). We always aim to dispatch all Royal Mail & DPD orders received before 15:00 the same working day. Any orders received after 15:00 or over the weekend will be dispatched the next working day. Orders will not be dispatched on weekends or bank holidays.

All orders are subject to approval by our team of doctors and pharmacists. Your delivery date in the checkout is subject to your consultation being approved by our healthcare team.

All orders can be fully tracked from your dispatch email, in your online account and from any notifications from your courier.

We ensure all parcels are in plain packaging for discreet delivery of your medicines and pharmacy goods. Where possible, we will attempt to size all parcels to fit through your letterbox in tamper-proof packaging. By placing an order on our website, you confirm that it is safe and appropriate for a package containing medicines to be posted through your letterbox, if the carrier is able to do so. You should notify our customer support team if it is not safe for the package to be posted through the letterbox, for example due to animals or small children.

Deliveries containing pharmacy-only or prescription medicines may require a signature on receipt. 

Delivery is free for all NHS prescriptions.


Royal Mail


  • Fully tracked delivery
  • SMS & email notifications
  • Four-hour delivery window
  • Change delivery date directly with Royal Mail
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local Post Office or Royal Mail Customer Service Point.

Royal Mail are the most widely recognised mail delivery company in the UK. Being on the UK’s 29 million doorsteps six days a week means they offer unparalleled price and convenience. The Independent Pharmacy uses Royal Mail’s Tracked 48, Tracked 24, and Special Delivery Guaranteed parcel services to offer reliable, fully-tracked delivery at very competitive prices. Your Royal Mail parcel will arrive with your normal daily delivery of post.

Please note: Royal Mail do not deliver on Sundays or Bank Holidays - this should be taken into account when ordering. 

If you are not home to accept your delivery, a card should be left by the Royal Mail representative. This card will provide details of where you can collect the order or how to arrange re-delivery.

Should you be unable to collect your missed delivery or arrange for your medication to be redelivered by Royal Mail, the pharmacy can resend your medication to the same, or a different address provided it has been returned to us and this happens within a 30 day window.

Once a package has been shipped with Royal Mail we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.




  • Fully tracked delivery
  • SMS & email notifications
  • One-hour delivery window
  • Change delivery date directly with DPD
  • Update delivery location - add a Safeplace, preferred neighbour, or update your delivery location to a local collection point.

DPD Local is the most innovative parcel carrier around. Thanks to their industry-leading Predict service, they provide parcel recipients with a one hour delivery window, notified by email, so you don't have to wait in all day. What's more, it enables receivers to watch the progress of their delivery on a real-time map, all the way down to a final 15 minute time-slot. 

As well as keeping customers informed at every stage of the journey, DPD believe in maximising choice and convenience. That's why DPD provide access to a suite of options both on the day of delivery and the night before, allowing customers to take delivery of their goods in a way that suits. If you wish to reschedule, you can:

  • Select an alternative delivery date
  • Opt for delivery to a nominated neighbour
  • Have the parcel left in a specified safe place
  • Collect the parcel from your local DPD Pickup Shop
  • Upgrade delivery to By 12

Please note: DPD do not deliver on Saturdays, Sundays or Bank Holidays - this should be taken into account when ordering. 

Once a package has been shipped with DPD we advise that you are bound to the terms and conditions of their use together with the terms and conditions contained herein.

You have the right to cancel your order up to the point when your treatment is dispatched. The pharmacist must destroy any medication within 30 days of it being returned, even un-opened boxes, so we are not able to offer refunds once your treatment has been dispatched.


Forwarding houses

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.


BFPO Postcodes

Unfortunately we are unable to deliver medicines to BFPO postcodes.


Remote Areas

Please be aware that Royal Mail Guaranteed services are not available to all customers in the UK, especially those that live in remote postcodes. Royal Mail advise customers of the following:

We deliver by 17:30 the next working day in the following postcode areas:
AB30 - 39, 41 - 45, 51 - 56
GY9 Alderney (Channel Islands)
HS1, 3 - 9
IV21 - 28, 40 - 49, 51 - 56
KA27, 28
KW1 - 3, 5 - 15
KW16 Stromness Town only
PA20 (0&9)
PA28 - 38, 41 - 49, 76, 77
PH15, 17 - 26, 31 - 40, 49, 50


We deliver within two working days by 17:30 to the following postcodes areas:
GY1 Herm (Channel Islands)
GY9 Sark (Channel Islands)
PA60 - 75, 78
ZE2, 3


We deliver within three working days by 17:30 to the following postcode areas:
KW16 - non-Town
PH30, 41 - 44


Please note: This applies to our 'Special Delivery' and 'Saturday Guaranteed' services.


International Orders

We are currently unable to ship orders outside of the UK.

We are unable to ship orders to mailing or forwarding houses for onwards shipping to locations outside of the UK.

Need to know more about Migraine?

Visit our advice area or contact our support team

Propranolol 40mg Tablets Reviews

Unsure about a treatment?
Ask our medical team for impartial information and advice about any treatment we provide or medical condition that we treat before you buy.

Authored By:

A photo of  Leanne Sinclair

Leanne Sinclair


Published on: 15-09-2016

Last modified on: 15-09-2018

Leanne is a clinical pharmacist with years of experience working in pharmacy.

Reviewed By:

A photo of Dr Donald Grant

Dr Donald Grant

MB ChB DRCOG MRCGP Dip.orth.med

Reviewed on: 15-09-2020

Next review date: 15-09-2022

Dr Don Grant is a GP with over 30 years experience and is the Clinical Advisor at The Independent Pharmacy

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